메뉴 건너뛰기




Volumn 2, Issue 9, 2011, Pages

Generation and characterization of antibodies specific for caspase-cleaved neo-epitopes: A novel approach

Author keywords

Apoptosis; Biomarker; Neo epitope antibodies

Indexed keywords

ANTIGEN; CASPASE; EPITOPE; MONOCLONAL ANTIBODY; PROTEINASE;

EID: 80053387466     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2011.91     Document Type: Article
Times cited : (17)

References (21)
  • 1
    • 33746886979 scopus 로고    scopus 로고
    • Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
    • DOI 10.1038/sj.onc.1209608, PII 1209608
    • Fulda S, Debatin KM. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 2006; 25: 4798-4811. (Pubitemid 44187627)
    • (2006) Oncogene , vol.25 , Issue.34 , pp. 4798-4811
    • Fulda, S.1    Debatin, K.-M.2
  • 2
    • 69849092354 scopus 로고    scopus 로고
    • Exploiting apoptosis pathways for the treatment of pediatric cancers
    • Fulda S. Exploiting apoptosis pathways for the treatment of pediatric cancers. Pediatr Blood Cancer 2009; 53: 533-536.
    • (2009) Pediatr Blood Cancer , vol.53 , pp. 533-536
    • Fulda, S.1
  • 3
    • 33845293253 scopus 로고    scopus 로고
    • Pharmacodynamic biomarkers for molecular cancer therapeutics
    • Sarker D, Workman P. Pharmacodynamic biomarkers for molecular cancer therapeutics. Adv Cancer Res 2007; 96: 213-268.
    • (2007) Adv Cancer Res , vol.96 , pp. 213-268
    • Sarker, D.1    Workman, P.2
  • 4
    • 48249093095 scopus 로고    scopus 로고
    • Integration and use of biomarkers in drug development, regulation and clinical practice: A US regulatory perspective
    • Amur S, Frueh FW, Lesko LJ, Huang SM. Integration and use of biomarkers in drug development, regulation and clinical practice: a US regulatory perspective. Biomark Med 2008; 2: 305-311.
    • (2008) Biomark Med , vol.2 , pp. 305-311
    • Amur, S.1    Frueh, F.W.2    Lesko, L.J.3    Huang, S.M.4
  • 6
    • 77951666896 scopus 로고    scopus 로고
    • Serum biomarkers of cell death for monitoring therapy response of gastrointestinal carcinomas
    • Brandt D, Volkmann X, Anstatt M, Langer F, Manns MP, Schulze-Osthoff K et al. Serum biomarkers of cell death for monitoring therapy response of gastrointestinal carcinomas. Eur J Cancer 2010; 46: 1464-1473.
    • (2010) Eur J Cancer , vol.46 , pp. 1464-1473
    • Brandt, D.1    Volkmann, X.2    Anstatt, M.3    Langer, F.4    Manns, M.P.5    Schulze-Osthoff, K.6
  • 7
    • 0030576945 scopus 로고    scopus 로고
    • CPP32/Yama/apopain cleaves the catalytic component of DNA-dependent protein kinase in the holoenzyme
    • DOI 10.1016/0014-5793(96)00842-3
    • Teraoka H, Yumoto Y, Watanabe F, Tsukada K, Suwa A, Enari M et al. CPP32/Yama/ apopain cleaves the catalytic component of DNA-dependent protein kinase in the holoenzyme. FEBS Lett 1996; 393: 1-6. (Pubitemid 26298217)
    • (1996) FEBS Letters , vol.393 , Issue.1 , pp. 1-6
    • Teraoka, H.1    Yumoto, Y.2    Watanabe, F.3    Tsukada, K.4    Suwa, A.5    Enari, M.6    Nagata, S.7
  • 9
    • 68049091812 scopus 로고    scopus 로고
    • Serum efficacy biomarkers for oncology
    • Linder S, Alaiya A. Serum efficacy biomarkers for oncology. Biomark Med 2009; 3: 47-54.
    • (2009) Biomark Med , vol.3 , pp. 47-54
    • Linder, S.1    Alaiya, A.2
  • 10
    • 49549113643 scopus 로고    scopus 로고
    • Global mapping of the topography and magnitude of proteolytic events in apoptosis
    • Dix MM, Simon GM, Cravatt BF. Global mapping of the topography and magnitude of proteolytic events in apoptosis. Cell 2008; 134: 679-691.
    • (2008) Cell , vol.134 , pp. 679-691
    • Dix, M.M.1    Simon, G.M.2    Cravatt, B.F.3
  • 11
    • 0032032627 scopus 로고    scopus 로고
    • CD95 (Fas)-induced caspase-mediated proteolysis of NF-B
    • Ravi R, Bedi A, Fuchs EJ, Bedi A. CD95 (Fas)-induced caspase-mediated proteolysis of NF-kappa B. Cancer Res 1998; 58: 882-886. (Pubitemid 28182451)
    • (1998) Cancer Research , vol.58 , Issue.5 , pp. 882-886
    • Ravi, R.1    Bedi, A.2    Fuchs, E.J.3    Bedi, A.4
  • 12
    • 0032971746 scopus 로고    scopus 로고
    • Immunolocalization of caspase proteolysis in situ: Evidence for widespread caspase-mediated apoptosis of neurons and glia in the postnatal rat brain
    • DOI 10.1016/S0306-4522(99)00034-2, PII S0306452299000342
    • Siman R, Bozyczko-Coyne D, Meyer SL, Bhat RV. Immunolocalization of caspase proteolysis in situ: evidence for widespread caspase-mediated apoptosis of neurons and glia in the postnatal rat brain. Neuroscience 1999; 92: 1425-1442. (Pubitemid 29292578)
    • (1999) Neuroscience , vol.92 , Issue.4 , pp. 1425-1442
    • Siman, R.1    Bozyczko-Coyne, D.2    Meyer, S.L.3    Bhat, R.V.4
  • 13
    • 0033976156 scopus 로고    scopus 로고
    • C-Jun/AP-1 (N) directed antibodies cross-react with 'apoptosis-specific protein' which marks an autophagic process during neuronal apoptosis
    • DOI 10.1016/S0306-4522(99)00550-3, PII S0306452299005503
    • Terwel D, Van de Berg W. c-Jun/AP-1 (N) directed antibodies cross-react with 'apoptosisspecific protein' which marks an autophagic process during neuronal apoptosis. Neuroscience 2000; 96: 445-446. (Pubitemid 30100426)
    • (2000) Neuroscience , vol.96 , Issue.2 , pp. 445-446
    • Terwel, D.1    Van De Berg, W.2
  • 14
    • 0036062596 scopus 로고    scopus 로고
    • C-Jun-like immunoreactivity in apoptosis is the result of a crossreaction with neoantigenic sites exposed by caspase-3-mediated proteolysis
    • Ribera J, Ayala V, Esquerda JE. c-Jun-like immunoreactivity in apoptosis is the result of a crossreaction with neoantigenic sites exposed by caspase-3-mediated proteolysis. J Histochem Cytochem 2002; 50: 961-972. (Pubitemid 34774607)
    • (2002) Journal of Histochemistry and Cytochemistry , vol.50 , Issue.7 , pp. 961-972
    • Ribera, J.1    Ayala, V.2    Esquerda, J.E.3
  • 15
    • 0034999278 scopus 로고    scopus 로고
    • Antibodies against c-Jun N-terminal peptide cross-react with neo-epitopes emerging after caspase-mediated proteolysis during apoptosis
    • DOI 10.1046/j.1471-4159.2001.00314.x
    • Casas C, Ribera J, Esquerda JE. Antibodies against c-Jun N-terminal peptide cross-react with neo-epitopes emerging after caspase-mediated proteolysis during apoptosis. J Neurochem 2001; 77: 904-915. (Pubitemid 32466787)
    • (2001) Journal of Neurochemistry , vol.77 , Issue.3 , pp. 904-915
    • Casas, C.1    Ribera, J.2    Esquerda, J.E.3
  • 16
    • 52649141086 scopus 로고    scopus 로고
    • Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini
    • Mahrus S, Trinidad JC, Barkan DT, Sali A, Burlingame AL, Wells JA. Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini. Cell 2008; 134: 866-876.
    • (2008) Cell , vol.134 , pp. 866-876
    • Mahrus, S.1    Trinidad, J.C.2    Barkan, D.T.3    Sali, A.4    Burlingame, A.L.5    Wells, J.A.6
  • 17
    • 33947426526 scopus 로고    scopus 로고
    • The CASBAH: A searchable database of caspase substrates
    • DOI 10.1038/sj.cdd.4402103, PII 4402103
    • Luthi AU, Martin SJ. The CASBAH: a searchable database of caspase substrates. Cell Death Differ 2007; 14: 641-650. (Pubitemid 46444502)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.4 , pp. 641-650
    • Luthi, A.U.1    Martin, S.J.2
  • 18
    • 38949206865 scopus 로고    scopus 로고
    • Amino acid analysis of peptide loading ratios in conjugate vaccines: A comparison of direct electrochemical detection and 6-aminoquinolyl-N- hydroxysuccinimidyl carbamate pre-column derivatization methods
    • DOI 10.1021/bc700232z
    • Nahas DD, Palladino JS, Joyce JG, Hepler RW. Amino acid analysis of peptide loading ratios in conjugate vaccines: a comparison of direct electrochemical detection and 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate pre-column derivatization methods. Bioconjug Chem 2008; 19: 322-326. (Pubitemid 351213865)
    • (2008) Bioconjugate Chemistry , vol.19 , Issue.1 , pp. 322-326
    • Nahas, D.D.1    Palladino, J.S.2    Joyce, J.G.3    Hepler, R.W.4
  • 19
    • 0025133403 scopus 로고
    • Immunogenicity of a Haemophilus influenzae polysaccharide-Neisseria meningitidis outer membrane protein complex conjugate vaccine
    • Donnelly JJ, Deck RR, Liu MA. Immunogenicity of a Haemophilus influenzae polysaccharide-Neisseria meningitidis outer membrane protein complex conjugate vaccine. J Immunol 1990; 145: 3071-3079. (Pubitemid 20382582)
    • (1990) Journal of Immunology , vol.145 , Issue.9 , pp. 3071-3079
    • Donnelly, J.J.1    Deck, R.R.2    Liu, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.