Molecular dynamics simulations of human DNA methyltransferase 3B with selective inhibitor nanaomycin A

Journal of Structural Biology

Volumn 176, Issue 2, 2011, Pages 185-191

  Caulfield, Thomas ^a   Medina Franco, José L ^a  

^a TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

Cancer; DNA methylation; DNMT3B; Enzyme; Epigenetics; Inhibitor

Indexed keywords

AMINO ACID; ARGININE; ASPARAGINE; DNA METHYLTRANSFERASE 3B; GLUTAMINE; NANAOMYCIN A; S ADENOSYLMETHIONINE; WATER;

ARTICLE; DRUG BINDING; DRUG CONFORMATION; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; SIMULATION;

AMINO ACID MOTIFS; BINDING SITES; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EPIGENESIS, GENETIC; HUMANS; HYDROGEN BONDING; MOLECULAR DYNAMICS SIMULATION; NAPHTHOQUINONES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; S-ADENOSYLMETHIONINE; THERMODYNAMICS;

EID: 80053383964     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2011.07.015     Document Type: Article

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