Mitochondrial apoptosis contributes to the anti-cancer effect of Smilax glabra Roxb

Toxicology Letters

Volumn 207, Issue 2, 2011, Pages 112-120

  Gao, Yujing ^a,c   Su, Yahui ^a   Qu, Like ^a   Xu, Shuo ^b   Meng, Lin ^a   Cai, Shao Qing ^b   Shou, Chengchao ^a  

^a PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

Anti cancer effect; Apoptosis; Mitochondria; Smilax glabra Roxb.

Indexed keywords

ANTINEOPLASTIC AGENT; CALCIUM ION; CASPASE 3; CYTOCHROME C; DNA; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; SMILAX GLABRA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE REGULATION; CELL NUCLEUS; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DNA LADDER FORMATION; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME RELEASE; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MALE; MEDICINAL PLANT; MEMBRANE PERMEABILITY; MICROARRAY ANALYSIS; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SMILACACEAE; SMILAX GLABRA; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BREAST NEOPLASMS; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; HT29 CELLS; HUMANS; LIVER NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, INBRED ICR; MICE, NUDE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; NEOPLASM TRANSPLANTATION; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RHIZOME; SMILAX; STOMACH NEOPLASMS;

LILIACEAE; MURINAE; MUS; MUS MUSCULUS; SMILACACEAE; SMILAX GLABRA;

EID: 80053378854     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.08.024     Document Type: Article

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