Small-molecular virulence inhibitors show divergent and immunomodulatory effects in infection models of Salmonella enterica serovar Typhimurium

International Journal of Antimicrobial Agents

Volumn 38, Issue 5, 2011, Pages 409-416

  Puiac, Speranta ^a   Sem, Xiaohui ^a   Negrea, Aurel ^b   Rhen, Mikael ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Immunomodulation; Nitric oxide (NO); Omeprazole; Salicylidene acylhydrazides; Type three secretion system (T3SS)

Indexed keywords

HYDRAZIDE DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; INP 0010; N(G) METHYLARGININE; NITRIC OXIDE; OMEPRAZOLE; SALICYLIDENE ACYLHYDRAZIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL VIRULENCE; BACTERIOSTASIS; CELL ACTIVITY; CELL DIVISION; CELL STRAIN; CELL STRAIN RAW264.7; CONTROLLED STUDY; ENZYME INHIBITION; EPITHELIUM CELL; IMMUNOMODULATION; MOUSE; NONHUMAN; PATHOGENICITY ISLAND; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RESPIRATORY BURST; SALMONELLA ENTERICA; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL SECRETION SYSTEMS; CELL LINE; ENZYME INHIBITORS; HUMANS; HYDRAZINES; MACROPHAGES; MEMBRANE PROTEINS; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OMEPRAZOLE; RESPIRATORY BURST; SALMONELLA TYPHIMURIUM; VIRULENCE;

EID: 80053371955     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2011.06.009     Document Type: Article

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