Selective blockade of 5-HT7 receptors facilitates attentional set-shifting in stressed and control rats

Behavioural Brain Research

Volumn 226, Issue 1, 2012, Pages 118-123

  Nikiforuk, Agnieszka ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

5 HT7 receptors; Antidepressants; Cognition; Depression; Set shifting; Stress

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; ESCITALOPRAM; SEROTONIN 7 RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; ATTENTION; COGNITION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; IMMOBILIZATION STRESS; MALE; MENTAL PERFORMANCE; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; STRESS;

ANIMALS; ATTENTION; CITALOPRAM; DISCRIMINATION LEARNING; MALE; PHENOLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RESTRAINT, PHYSICAL; SEROTONIN ANTAGONISTS; SEROTONIN UPTAKE INHIBITORS; SET (PSYCHOLOGY); STRESS, PHYSIOLOGICAL; SULFONAMIDES;

EID: 80053356604     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.09.006     Document Type: Article

References (47)

1. Hedlund P.B. The 5-HT7 receptor and disorders of the nervous system: an overview. Psychopharmacology 2009, 206:345-354.
2. Leopoldo M., Lacivita E., Berardi F., Perrone R., Hedlund P.B. Serotonin 5-HT7 receptor agents: structure-activity relationships and potential therapeutic applications in central nervous system disorders. Pharmacol Ther 2011, 129:120-148.
3. Bonaventure P., Kelly L., Aluisio L., Shelton J., Lord B., Galici R., et al. Selective blockade of 5-hydroxytryptamine (5-HT)7 receptors enhances 5-ht transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents. J Pharmacol Exp Ther 2007, 321:690-698.
4. Hedlund P.B., Huitron-Resendiz S., Henriksen S.J., Sutcliffe J.G. 5-HT7 receptor inhibition and inactivation induce antidepressant like behavior and sleep pattern. Biol Psychiatry 2005, 58:831-837.
5. Wesolowska A., Nikiforuk A., Stachowicz K., Tatarczynska E. Effect of the selective 5-HT7 receptor antagonist SB 269970 in animal models of anxiety and depression. Neuropharmacology 2006, 51:578-586.
6. Wesolowska A., Kowalska M. Influence of serotonin 5-HT(7) receptor blockade on the behavioral and neurochemical effects of imipramine in rats. Pharmacol Rep 2008, 60:464-474.
7. Guscott M., Bristow L.J., Hadingham K., Rosahl T.W., Beer M.S., Stanton J.A., et al. Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression. Neuropharmacology 2005, 48:492-502.
8. Sarkisyan G., Roberts A.J., Hedlund P.B. The 5-HT7 receptor as a mediator and modulator of antidepressant-like behavior. Behav Brain Res 2010, 209:99-108.
9. Hagan J.J., Price G.W., Jeffrey P., Deeks N.J., Stean T., Piper D., et al. Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist. Br J Pharmacol 2000, 130:539-548.
10. Wesolowska A., Tatarczynska E., Nikiforuk A., Chojnacka-Wojcik E. Enhancement of the anti-immobility action of antidepressants by a selective 5-HT(7) receptor antagonist in the forced swimming test in mice. Eur J Pharmacol 2007, 555:43-47.
11. Shelton J., Bonaventure P., Li X.R., Yun S.J., Lovenberg T., Dugovic C. 5-HT7 receptor deletion enhances REM sleep suppression induced by selective serotonin reuptake inhibitors, but not by direct stimulation of 5-HT1A receptor. Neuropharmacology 2009, 56:448-454.
12. Cifariello A., Pompili A., Gasbarri A. 5-HT(7) receptors in the modulation of cognitive processes. Behav Brain Res 2008, 195:171-179.
13. Channon S. Executive dysfunction in depression: the Wisconsin Card Sorting Test. J Affect Disord 1996, 39:107-114.
14. Merriam E.P., Thase M.E., Haas G.L., Keshavan M.S., Sweeney J.A. Prefrontal cortical dysfunction in depression determined by Wisconsin Card Sorting Test performance. Am J Psychiatry 1999, 156:780-782.
15. Austin M-P., Ross M., Murray C., O'Carroll R.E., Ebmeier K.P., Goodwin G.M. Cognitive function in major depression. J Affect Disord 1992, 25:21-30.
16. Robinson L.J., Thompson J.M., Gallagher P., Goswami U., Young A.H., Ferrier I.N., et al. A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder. J Affect Disord 2006, 93:105-115.
17. Birrell J.M., Brown V.J. Medial frontal cortex mediates perceptual attentional set shifting in the rat. J Neurosci 2000, 20:4320-4324.
18. Anisman H., Matheson K. Stress, depression, and anhedonia: caveats concerning animal models. Neurosci Biobehav Rev 2005, 29:525-546.
19. Brown S.M., Henning S., Wellman C.L. Mild, short-term stress alters dendritic morphology in rat medial prefrontal cortex. Cereb Cortex 2005, 15:1714-1722.
20. Cook S.C., Wellman C.L. Chronic stress alters dendritic morphology in rat medial prefrontal cortex. J Neurobiol 2004, 60:236-248.
21. Radley J.J., Sisti H.M., Hao J., Rocher A.B., McCall T., Hof P.R., et al. Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex. Neuroscience 2004, 125:1-6.
22. Radley J.J., Rocher A.B., Miller M., Janssen W.G., Liston C., Hof P.R., et al. Repeated stress induces dendritic spine loss in the rat medial prefrontal cortex. Cereb Cortex 2006, 16:313-320.
23. Cerqueira J.J., Mailliet F., Almeida O.F., Jay T.M., Sousa N. The prefrontal cortex as a key target of the maladaptive response to stress. J Neurosci 2007, 27:2781-2787.
24. Liu R.J., Aghajanian G.K. Stress blunts serotonin- and hypocretin-evoked EPSCs in prefrontal cortex: role of corticosterone-mediated apical dendritic atrophy. Proc Natl Acad Sci USA 2008, 105:359-364.
25. Liston C., Miller M.M., Goldwater D.S., Radley J.J., Rocher A.B., Hof P.R., et al. Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting. J Neurosci 2006, 26:7870-7874.
26. Nikiforuk A., Popik P. Long-lasting cognitive deficit induced by stress is alleviated by acute administration of antidepressants. Psychoneuroendocrinology 2011, 36:28-39.
27. Nikiforuk A., Golembiowska K., Popik P. Mazindol attenuates ketamine-induced cognitive deficit in the attentional set shifting task in rats. Eur Neuropsychopharmacol 2010, 20:37-48.
28. Gasbarri A., Cifariello A., Pompili A., Meneses A. Effect of 5-HT7 antagonist SB-269970 in the modulation of working and reference memory in the rat. Behav Brain Res 2008, 195:164-170.
29. Sanchez C., Bergqvist P.B., Brennum L.T., Gupta S., Hogg S., Larsen A., et al. Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities. Psychopharmacology (Berl) 2003, 167:353-362.
30. Robbins T.W. Chemical neuromodulation of frontal-executive functions in humans and other animals. Exp Brain Res 2000, 133:130-138.
31. Clarke H.F., Walker S.C., Crofts H.S., Dalley J.W., Robbins T.W., Roberts A.C. Prefrontal serotonin depletion affects reversal learning but not attentional set shifting. J Neurosci 2005, 25:532-538.
32. Lapiz-Bluhm M.D., Soto-Pina A.E., Hensler J.G., Morilak D.A. Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats. Psychopharmacology (Berl) 2009, 202:329-341.
33. Homberg J.R., Pattij T., Janssen M.C., Ronken E., De Boer S.F., Schoffelmeer A.N., et al. Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. Eur J Neurosci 2007, 26:2066-2073.
34. Meneses A. Effects of the 5-HT7 receptor antagonists SB-269970 and DR 4004 in autoshaping Pavlovian/instrumental learning task. Behav Brain Res 2004, 155:275-282.
35. Sarkisyan G., Hedlund P.B. The 5-HT7 receptor is involved in allocentric spatial memory information processing. Behav Brain Res 2009, 202:26-31.
36. McLean S.L., Woolley M.L., Thomas D., Neill J.C. Role of 5-HT receptor mechanisms in sub-chronic PCP-induced reversal learning deficits in the rat. Psychopharmacology (Berl) 2009, 206:403-414.
37. Horiguchi M., Huang M., Meltzer H.Y. The role of 5-hydroxytryptamine 7 receptors in the phencyclidine-induced novel object recognition deficit in rats. J Pharmacol Exp Ther 2011, 338:605-614.
38. Bonaventure P., Aluisio L., Shoblock J., Boggs J.D., Fraser I.C., Lord B., et al. Pharmacological blockade of serotonin 5-HT(7) receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission. PLoS One 2011, 6:e20210.
39. Liy-Salmeron G., Meneses A. Effects of 5-HT drugs in prefrontal cortex during memory formation and the ketamine amnesia-model. Hippocampus 2008, 18:965-974.
40. Abbas A.I., Hedlund P.B., Huang X.P., Tran T.B., Meltzer H.Y., Roth B.L. Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo. Psychopharmacology (Berl) 2009, 205:119-128.
41. Ishibashi T., Horisawa T., Tokuda K., Ishiyama T., Ogasa M., Tagashira R., et al. Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity. J Pharmacol Exp Ther 2010, 334:171-181.
42. Jensen N.H., Rodriguiz R.M., Caron M.G., Wetsel W.C., Rothman R.B., Roth B.L., et al. a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity. Neuropsychopharmacology 2008, 33:2303-2312.
43. Tokarski K., Zahorodna A., Bobula B., Grzegorzewska M., Pitra P., Hess G. Repeated administration of citalopram and imipramine alters the responsiveness of rat hippocampal circuitry to the activation of 5-HT7 receptors. Eur J Pharmacol 2005, 524:60-66.
44. Yau J.L., Noble J., Seckl J.R. Acute restraint stress increases 5-HT7 receptor mRNA expression in the rat hippocampus. Neurosci Lett 2001, 309:141-144.
45. Le Corre S., Sharp T., Young A.H., Harrison P.J. Increase of 5-HT7 (serotonin-7) and 5-HT1A (serotonin-1A) receptor mRNA expression in rat hippocampus after adrenalectomy. Psychopharmacology (Berl) 1997, 130:368-374.
46. Yau J.L., Noble J., Widdowson J., Seckl J.R. Impact of adrenalectomy on 5-HT6 and 5-HT7 receptor gene expression in the rat hippocampus. Brain Res Mol Brain Res 1997, 45:182-186.
47. Li Y.C., Wang F.M., Pan Y., Qiang L.Q., Cheng G., Zhang W.Y., et al. Antidepressant-like effects of curcumin on serotonergic receptor-coupled AC-cAMP pathway in chronic unpredictable mild stress of rats. Prog Neuropsychopharmacol Biol Psychiatry 2009, 33:435-449.