-
1
-
-
33847065486
-
The epigenomics of cancer
-
10.1016/j.cell.2007.01.029, 17320506
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007, 128:683-692. 10.1016/j.cell.2007.01.029, 17320506.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
2
-
-
0034744639
-
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
-
10.1093/hmg/10.7.687, 11257100
-
Baylin SB, Esteller M, Rountree MR, Bachman KE, Schuebel K, Herman JG. Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet 2001, 10:687-692. 10.1093/hmg/10.7.687, 11257100.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 687-692
-
-
Baylin, S.B.1
Esteller, M.2
Rountree, M.R.3
Bachman, K.E.4
Schuebel, K.5
Herman, J.G.6
-
3
-
-
17444417521
-
Cancer epigenetics
-
Laird PW. Cancer epigenetics. Hum Mol Genet 2005, 14(Spec No 1):R65-76.
-
(2005)
Hum Mol Genet
, vol.14
, Issue.SPEC NO 1
-
-
Laird, P.W.1
-
4
-
-
0037068353
-
DNA methylation in cancer: too much, but also too little
-
10.1038/sj.onc.1205651, 12154403
-
Ehrlich M. DNA methylation in cancer: too much, but also too little. Oncogene 2002, 21:5400-5413. 10.1038/sj.onc.1205651, 12154403.
-
(2002)
Oncogene
, vol.21
, pp. 5400-5413
-
-
Ehrlich, M.1
-
5
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
10.1056/NEJMra023075, 14627790
-
Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003, 349:2042-2054. 10.1056/NEJMra023075, 14627790.
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
6
-
-
33747889966
-
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma
-
10.1158/0008-5472.CAN-05-4552, 16885346
-
Kim TY, Zhong S, Fields CR, Kim JH, Robertson KD. Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Res 2006, 66:7490-7501. 10.1158/0008-5472.CAN-05-4552, 16885346.
-
(2006)
Cancer Res
, vol.66
, pp. 7490-7501
-
-
Kim, T.Y.1
Zhong, S.2
Fields, C.R.3
Kim, J.H.4
Robertson, K.D.5
-
7
-
-
0037227642
-
DNA repair gene O6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors
-
10.1002/mc.10094, 12503076
-
Yin D, Xie D, Hofmann WK, Zhang W, Asotra K, Wong R, Black KL, Koeffler HP. DNA repair gene O6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors. Mol Carcinog 2003, 36:23-31. 10.1002/mc.10094, 12503076.
-
(2003)
Mol Carcinog
, vol.36
, pp. 23-31
-
-
Yin, D.1
Xie, D.2
Hofmann, W.K.3
Zhang, W.4
Asotra, K.5
Wong, R.6
Black, K.L.7
Koeffler, H.P.8
-
8
-
-
12144291692
-
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide
-
10.1158/1078-0432.CCR-03-0384, 15041700
-
Hegi ME, Diserens AC, Godard S, Dietrich PY, Regli L, Ostermann S, Otten P, Van Melle G, de Tribolet N, Stupp R. Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. Clin Cancer Res 2004, 10:1871-1874. 10.1158/1078-0432.CCR-03-0384, 15041700.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1871-1874
-
-
Hegi, M.E.1
Diserens, A.C.2
Godard, S.3
Dietrich, P.Y.4
Regli, L.5
Ostermann, S.6
Otten, P.7
Van Melle, G.8
de Tribolet, N.9
Stupp, R.10
-
9
-
-
0037393981
-
Promoter hypermethylation of the DNA repair gene O6-methylguanine-DNA methyltransferase is an independent predictor of shortened progression free survival in patients with low-grade diffuse astrocytomas
-
Komine C, Watanabe T, Katayama Y, Yoshino A, Yokoyama T, Fukushima T. Promoter hypermethylation of the DNA repair gene O6-methylguanine-DNA methyltransferase is an independent predictor of shortened progression free survival in patients with low-grade diffuse astrocytomas. Brain Pathol 2003, 13:176-184.
-
(2003)
Brain Pathol
, vol.13
, pp. 176-184
-
-
Komine, C.1
Watanabe, T.2
Katayama, Y.3
Yoshino, A.4
Yokoyama, T.5
Fukushima, T.6
-
10
-
-
33847242813
-
Aberrant promoter hypermethylation profile of cell cycle regulatory genes in malignant astrocytomas
-
Ohta T, Watanabe T, Katayama Y, Yoshino A, Yachi K, Ogino A, Komine C, Fukushima T. Aberrant promoter hypermethylation profile of cell cycle regulatory genes in malignant astrocytomas. Oncol Rep 2006, 16:957-963.
-
(2006)
Oncol Rep
, vol.16
, pp. 957-963
-
-
Ohta, T.1
Watanabe, T.2
Katayama, Y.3
Yoshino, A.4
Yachi, K.5
Ogino, A.6
Komine, C.7
Fukushima, T.8
-
11
-
-
57049167001
-
Promoter hypermethylation-mediated inactivation of LRRC4 in gliomas
-
10.1186/1471-2199-9-99, 2588634, 18976507
-
Zhang Z, Li D, Wu M, Xiang B, Wang L, Zhou M, Chen P, Li X, Shen S, Li G. Promoter hypermethylation-mediated inactivation of LRRC4 in gliomas. BMC Mol Biol 2008, 9:99. 10.1186/1471-2199-9-99, 2588634, 18976507.
-
(2008)
BMC Mol Biol
, vol.9
, pp. 99
-
-
Zhang, Z.1
Li, D.2
Wu, M.3
Xiang, B.4
Wang, L.5
Zhou, M.6
Chen, P.7
Li, X.8
Shen, S.9
Li, G.10
-
12
-
-
0344873729
-
Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors
-
10.1038/sj.onc.1207082, 14586413
-
Horiguchi K, Tomizawa Y, Tosaka M, Ishiuchi S, Kurihara H, Mori M, Saito N. Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors. Oncogene 2003, 22:7862-7865. 10.1038/sj.onc.1207082, 14586413.
-
(2003)
Oncogene
, vol.22
, pp. 7862-7865
-
-
Horiguchi, K.1
Tomizawa, Y.2
Tosaka, M.3
Ishiuchi, S.4
Kurihara, H.5
Mori, M.6
Saito, N.7
-
13
-
-
24344509239
-
TP53 promoter methylation in human gliomas
-
10.1007/s00401-005-1041-5, 16025287
-
Amatya VJ, Naumann U, Weller M, Ohgaki H. TP53 promoter methylation in human gliomas. Acta Neuropathol 2005, 110:178-184. 10.1007/s00401-005-1041-5, 16025287.
-
(2005)
Acta Neuropathol
, vol.110
, pp. 178-184
-
-
Amatya, V.J.1
Naumann, U.2
Weller, M.3
Ohgaki, H.4
-
14
-
-
1842536844
-
Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas
-
10.1038/sj.onc.1207407, 14743209
-
Hesson L, Bieche I, Krex D, Criniere E, Hoang-Xuan K, Maher ER, Latif F. Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas. Oncogene 2004, 23:2408-2419. 10.1038/sj.onc.1207407, 14743209.
-
(2004)
Oncogene
, vol.23
, pp. 2408-2419
-
-
Hesson, L.1
Bieche, I.2
Krex, D.3
Criniere, E.4
Hoang-Xuan, K.5
Maher, E.R.6
Latif, F.7
-
15
-
-
34547432233
-
Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma
-
10.1215/15228517-2007-003, 1907411, 17504928
-
Wiencke JK, Zheng S, Jelluma N, Tihan T, Vandenberg S, Tamguney T, Baumber R, Parsons R, Lamborn KR, Berger MS, Wrensch MR, Haas-Kogan DA, Stokoe D. Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma. Neuro Oncol 2007, 9:271-279. 10.1215/15228517-2007-003, 1907411, 17504928.
-
(2007)
Neuro Oncol
, vol.9
, pp. 271-279
-
-
Wiencke, J.K.1
Zheng, S.2
Jelluma, N.3
Tihan, T.4
Vandenberg, S.5
Tamguney, T.6
Baumber, R.7
Parsons, R.8
Lamborn, K.R.9
Berger, M.S.10
Wrensch, M.R.11
Haas-Kogan, D.A.12
Stokoe, D.13
-
16
-
-
14644396175
-
Promoter hypermethylation of mismatch repair gene hMLH1 predicts the clinical response of malignant astrocytomas to nitrosourea
-
10.1158/1078-0432.CCR-04-1625, 15746058
-
Fukushima T, Katayama Y, Watanabe T, Yoshino A, Ogino A, Ohta T, Komine C. Promoter hypermethylation of mismatch repair gene hMLH1 predicts the clinical response of malignant astrocytomas to nitrosourea. Clin Cancer Res 2005, 11:1539-1544. 10.1158/1078-0432.CCR-04-1625, 15746058.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1539-1544
-
-
Fukushima, T.1
Katayama, Y.2
Watanabe, T.3
Yoshino, A.4
Ogino, A.5
Ohta, T.6
Komine, C.7
-
17
-
-
0034795045
-
Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G: C - A: T mutations of the TP53 tumor suppressor gene
-
10.1093/carcin/22.10.1715, 11577014
-
Nakamura M, Watanabe T, Yonekawa Y, Kleihues P, Ohgaki H. Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G: C - A: T mutations of the TP53 tumor suppressor gene. Carcinogenesis 2001, 22:1715-1719. 10.1093/carcin/22.10.1715, 11577014.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1715-1719
-
-
Nakamura, M.1
Watanabe, T.2
Yonekawa, Y.3
Kleihues, P.4
Ohgaki, H.5
-
18
-
-
15744392240
-
Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas
-
10.1593/neo.04490, 1501138, 15799819
-
Waha A, Guntner S, Huang TH, Yan PS, Arslan B, Pietsch T, Wiestler OD. Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas. Neoplasia 2005, 7:193-199. 10.1593/neo.04490, 1501138, 15799819.
-
(2005)
Neoplasia
, vol.7
, pp. 193-199
-
-
Waha, A.1
Guntner, S.2
Huang, T.H.3
Yan, P.S.4
Arslan, B.5
Pietsch, T.6
Wiestler, O.D.7
-
19
-
-
4644314826
-
Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma
-
10.1016/S0002-9440(10)63376-7, 1618625, 15466382
-
Stone AR, Bobo W, Brat DJ, Devi NS, Van Meir EG, Vertino PM. Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma. Am J Pathol 2004, 165:1151-1161. 10.1016/S0002-9440(10)63376-7, 1618625, 15466382.
-
(2004)
Am J Pathol
, vol.165
, pp. 1151-1161
-
-
Stone, A.R.1
Bobo, W.2
Brat, D.J.3
Devi, N.S.4
Van Meir, E.G.5
Vertino, P.M.6
-
20
-
-
0037007175
-
Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases
-
10.1002/1439-7633(20020402)3:4<274::AID-CBIC274>3.0.CO;2-S, 11933228
-
Jeltsch A. Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases. Chembiochem 2002, 3:274-293. 10.1002/1439-7633(20020402)3:4<274::AID-CBIC274>3.0.CO;2-S, 11933228.
-
(2002)
Chembiochem
, vol.3
, pp. 274-293
-
-
Jeltsch, A.1
-
21
-
-
68049116936
-
DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis
-
10.1038/onc.2009.122, 19465937
-
Foltz G, Yoon JG, Lee H, Ryken TC, Sibenaller Z, Ehrich M, Hood L, Madan A. DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis. Oncogene 2009, 28:2667-2677. 10.1038/onc.2009.122, 19465937.
-
(2009)
Oncogene
, vol.28
, pp. 2667-2677
-
-
Foltz, G.1
Yoon, J.G.2
Lee, H.3
Ryken, T.C.4
Sibenaller, Z.5
Ehrich, M.6
Hood, L.7
Madan, A.8
-
22
-
-
38049148239
-
Loss of pericentromeric DNA methylation pattern in human glioblastoma is associated with altered DNA methyltransferases expression and involves the stem cell compartment
-
10.1038/sj.onc.1210642, 17653095
-
Fanelli M, Caprodossi S, Ricci-Vitiani L, Porcellini A, Tomassoni-Ardori F, Amatori S, Andreoni F, Magnani M, De Maria R, Santoni A, Minucci S, Pelicci PG. Loss of pericentromeric DNA methylation pattern in human glioblastoma is associated with altered DNA methyltransferases expression and involves the stem cell compartment. Oncogene 2008, 27:358-365. 10.1038/sj.onc.1210642, 17653095.
-
(2008)
Oncogene
, vol.27
, pp. 358-365
-
-
Fanelli, M.1
Caprodossi, S.2
Ricci-Vitiani, L.3
Porcellini, A.4
Tomassoni-Ardori, F.5
Amatori, S.6
Andreoni, F.7
Magnani, M.8
De Maria, R.9
Santoni, A.10
Minucci, S.11
Pelicci, P.G.12
-
23
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
10.1016/S0092-8674(04)00045-5, 14744438
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297. 10.1016/S0092-8674(04)00045-5, 14744438.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
24
-
-
3042767202
-
MicroRNAs: small RNAs with a big role in gene regulation
-
10.1038/nrg1379, 15211354
-
He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 2004, 5:522-531. 10.1038/nrg1379, 15211354.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
25
-
-
33744805399
-
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
-
10.1016/j.ccr.2006.04.020, 16766263
-
Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA, Jones PA. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006, 9:435-443. 10.1016/j.ccr.2006.04.020, 16766263.
-
(2006)
Cancer Cell
, vol.9
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
Friedman, J.M.4
Chuang, J.C.5
Coetzee, G.A.6
Jones, P.A.7
-
26
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
10.1073/pnas.0707628104, 2000384, 17890317
-
Fabbri M, Garzon R, Cimmino A, Liu Z, Zanesi N, Callegari E, Liu S, Alder H, Costinean S, Fernandez-Cymering C, Volinia S, Guler G, Morrison CD, Chan KK, Marcucci G, Calin GA, Huebner K, Croce CM. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA 2007, 104:15805-15810. 10.1073/pnas.0707628104, 2000384, 17890317.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
Liu, Z.4
Zanesi, N.5
Callegari, E.6
Liu, S.7
Alder, H.8
Costinean, S.9
Fernandez-Cymering, C.10
Volinia, S.11
Guler, G.12
Morrison, C.D.13
Chan, K.K.14
Marcucci, G.15
Calin, G.A.16
Huebner, K.17
Croce, C.M.18
-
27
-
-
51649083501
-
A microRNA DNA methylation signature for human cancer metastasis
-
10.1073/pnas.0803055105, 2528872, 18768788
-
Lujambio A, Calin GA, Villanueva A, Ropero S, Sanchez-Cespedes M, Blanco D, Montuenga LM, Rossi S, Nicoloso MS, Faller WJ, Gallagher WM, Eccles SA, Croce CM, Esteller M. A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci USA 2008, 105:13556-13561. 10.1073/pnas.0803055105, 2528872, 18768788.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13556-13561
-
-
Lujambio, A.1
Calin, G.A.2
Villanueva, A.3
Ropero, S.4
Sanchez-Cespedes, M.5
Blanco, D.6
Montuenga, L.M.7
Rossi, S.8
Nicoloso, M.S.9
Faller, W.J.10
Gallagher, W.M.11
Eccles, S.A.12
Croce, C.M.13
Esteller, M.14
-
28
-
-
48549091046
-
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis
-
10.1158/0008-5472.CAN-07-6655, 2562630, 18593903
-
Datta J, Kutay H, Nasser MW, Nuovo GJ, Wang B, Majumder S, Liu CG, Volinia S, Croce CM, Schmittgen TD, Ghoshal K, Jacob ST. Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res 2008, 68:5049-5058. 10.1158/0008-5472.CAN-07-6655, 2562630, 18593903.
-
(2008)
Cancer Res
, vol.68
, pp. 5049-5058
-
-
Datta, J.1
Kutay, H.2
Nasser, M.W.3
Nuovo, G.J.4
Wang, B.5
Majumder, S.6
Liu, C.G.7
Volinia, S.8
Croce, C.M.9
Schmittgen, T.D.10
Ghoshal, K.11
Jacob, S.T.12
-
29
-
-
49249121155
-
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
-
10.1158/0008-5472.CAN-08-0325, 18519671
-
Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, Tokino T. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res 2008, 68:4123-4132. 10.1158/0008-5472.CAN-08-0325, 18519671.
-
(2008)
Cancer Res
, vol.68
, pp. 4123-4132
-
-
Toyota, M.1
Suzuki, H.2
Sasaki, Y.3
Maruyama, R.4
Imai, K.5
Shinomura, Y.6
Tokino, T.7
-
30
-
-
40949100837
-
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
-
10.1038/nsmb.1399, 21966493
-
Benetti R, Gonzalo S, Jaco I, Munoz P, Gonzalez S, Schoeftner S, Murchison E, Andl T, Chen TP, Klatt P, Li E, Serrano M, Millar S, Hannon G, Blasco MA. A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nature Structural & Molecular Biology 2008, 15:268-279. 10.1038/nsmb.1399, 21966493.
-
(2008)
Nature Structural & Molecular Biology
, vol.15
, pp. 268-279
-
-
Benetti, R.1
Gonzalo, S.2
Jaco, I.3
Munoz, P.4
Gonzalez, S.5
Schoeftner, S.6
Murchison, E.7
Andl, T.8
Chen, T.P.9
Klatt, P.10
Li, E.11
Serrano, M.12
Millar, S.13
Hannon, G.14
Blasco, M.A.15
-
31
-
-
77951974552
-
DNA methylation mediated by a microRNA pathway
-
10.1016/j.molcel.2010.03.008, 20381393
-
Wu L, Zhou H, Zhang Q, Zhang J, Ni F, Liu C, Qi Y. DNA methylation mediated by a microRNA pathway. Mol Cell 2010, 38:465-475. 10.1016/j.molcel.2010.03.008, 20381393.
-
(2010)
Mol Cell
, vol.38
, pp. 465-475
-
-
Wu, L.1
Zhou, H.2
Zhang, Q.3
Zhang, J.4
Ni, F.5
Liu, C.6
Qi, Y.7
-
32
-
-
39149133183
-
Methyl-DNA immunoprecipitation (MeDIP): hunting down the DNA methylome
-
35, 37, 39 passim
-
Jacinto FV, Ballestar E, Esteller M. Methyl-DNA immunoprecipitation (MeDIP): hunting down the DNA methylome. Biotechniques 2008, 44. 35, 37, 39 passim.
-
(2008)
Biotechniques
, vol.44
-
-
Jacinto, F.V.1
Ballestar, E.2
Esteller, M.3
-
33
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
10.1007/s00401-007-0243-4, 1929165, 17618441
-
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007, 114:97-109. 10.1007/s00401-007-0243-4, 1929165, 17618441.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
Scheithauer, B.W.7
Kleihues, P.8
-
34
-
-
27644548948
-
Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry
-
10.1073/pnas.0507816102, 1276092, 16243968
-
Ehrich M, Nelson MR, Stanssens P, Zabeau M, Liloglou T, Xinarianos G, Cantor CR, Field JK, van den Boom D. Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry. Proc Natl Acad Sci USA 2005, 102:15785-15790. 10.1073/pnas.0507816102, 1276092, 16243968.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15785-15790
-
-
Ehrich, M.1
Nelson, M.R.2
Stanssens, P.3
Zabeau, M.4
Liloglou, T.5
Xinarianos, G.6
Cantor, C.R.7
Field, J.K.8
van den Boom, D.9
-
35
-
-
33746607239
-
LRRC4, a putative tumor suppressor gene, requires a functional leucine-rich repeat cassette domain to inhibit proliferation of glioma cells in vitro by modulating the extracellular signal-regulated kinase/protein kinase B/nuclear factor-kappaB pathway
-
10.1091/mbc.E05-11-1082, 1525233, 16723503
-
Wu M, Huang C, Gan K, Huang H, Chen Q, Ouyang J, Tang Y, Li X, Yang Y, Zhou H, Zhou Y, Zeng Z, Xiao L, Li D, Tang K, Shen S, Li G. LRRC4, a putative tumor suppressor gene, requires a functional leucine-rich repeat cassette domain to inhibit proliferation of glioma cells in vitro by modulating the extracellular signal-regulated kinase/protein kinase B/nuclear factor-kappaB pathway. Mol Biol Cell 2006, 17:3534-3542. 10.1091/mbc.E05-11-1082, 1525233, 16723503.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 3534-3542
-
-
Wu, M.1
Huang, C.2
Gan, K.3
Huang, H.4
Chen, Q.5
Ouyang, J.6
Tang, Y.7
Li, X.8
Yang, Y.9
Zhou, H.10
Zhou, Y.11
Zeng, Z.12
Xiao, L.13
Li, D.14
Tang, K.15
Shen, S.16
Li, G.17
-
36
-
-
21244449980
-
Evaluation of a 7-day continuous intravenous infusion of decitabine: Inhibition of promoter-specific and global genomic DNA methylation
-
10.1200/JCO.2005.06.118, 15753459
-
Samlowski WE, Leachman SA, Wade M, Cassidy P, Porter-Gill P, Busby L, Wheeler R, Boucher K, Fitzpatrick F, Jones DA, Karpf AR. Evaluation of a 7-day continuous intravenous infusion of decitabine: Inhibition of promoter-specific and global genomic DNA methylation. Journal of Clinical Oncology 2005, 23:3897-3905. 10.1200/JCO.2005.06.118, 15753459.
-
(2005)
Journal of Clinical Oncology
, vol.23
, pp. 3897-3905
-
-
Samlowski, W.E.1
Leachman, S.A.2
Wade, M.3
Cassidy, P.4
Porter-Gill, P.5
Busby, L.6
Wheeler, R.7
Boucher, K.8
Fitzpatrick, F.9
Jones, D.A.10
Karpf, A.R.11
-
37
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang DW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nature Protocols 2009, 4:44-57.
-
(2009)
Nature Protocols
, vol.4
, pp. 44-57
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
-
38
-
-
42549135582
-
Frequent biallelic inactivation and transcriptional silencing of the DIRAS3 gene at 1p31 in oligodendroglial tumors with 1p loss
-
10.1002/ijc.23409, 18302158
-
Riemenschneider MJ, Reifenberger J, Reifenberger G. Frequent biallelic inactivation and transcriptional silencing of the DIRAS3 gene at 1p31 in oligodendroglial tumors with 1p loss. Int J Cancer 2008, 122:2503-2510. 10.1002/ijc.23409, 18302158.
-
(2008)
Int J Cancer
, vol.122
, pp. 2503-2510
-
-
Riemenschneider, M.J.1
Reifenberger, J.2
Reifenberger, G.3
-
39
-
-
34247485737
-
Promoter hypermethylation identifies progression risk in bladder cancer
-
10.1158/1078-0432.CCR-06-2476, 17404085
-
Yates DR, Rehman I, Abbod MF, Meuth M, Cross SS, Linkens DA, Hamdy FC, Catto JW. Promoter hypermethylation identifies progression risk in bladder cancer. Clin Cancer Res 2007, 13:2046-2053. 10.1158/1078-0432.CCR-06-2476, 17404085.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2046-2053
-
-
Yates, D.R.1
Rehman, I.2
Abbod, M.F.3
Meuth, M.4
Cross, S.S.5
Linkens, D.A.6
Hamdy, F.C.7
Catto, J.W.8
-
40
-
-
49449117541
-
Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia
-
10.1038/leu.2008.130, 18528427
-
Kuang SQ, Tong WG, Yang H, Lin W, Lee MK, Fang ZH, Wei Y, Jelinek J, Issa JP, Garcia-Manero G. Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia. Leukemia 2008, 22:1529-1538. 10.1038/leu.2008.130, 18528427.
-
(2008)
Leukemia
, vol.22
, pp. 1529-1538
-
-
Kuang, S.Q.1
Tong, W.G.2
Yang, H.3
Lin, W.4
Lee, M.K.5
Fang, Z.H.6
Wei, Y.7
Jelinek, J.8
Issa, J.P.9
Garcia-Manero, G.10
-
41
-
-
77950813610
-
CpG island hypermethylation in human astrocytomas
-
10.1158/0008-5472.CAN-09-3631, 2848870, 20233874
-
Wu X, Rauch TA, Zhong X, Bennett WP, Latif F, Krex D, Pfeifer GP. CpG island hypermethylation in human astrocytomas. Cancer Res 2010, 70:2718-2727. 10.1158/0008-5472.CAN-09-3631, 2848870, 20233874.
-
(2010)
Cancer Res
, vol.70
, pp. 2718-2727
-
-
Wu, X.1
Rauch, T.A.2
Zhong, X.3
Bennett, W.P.4
Latif, F.5
Krex, D.6
Pfeifer, G.P.7
-
42
-
-
67449113765
-
Methylation of RASSF1A, RASSF2A, and HIN-1 is associated with poor outcome after radiotherapy, but not surgery, in oral squamous cell carcinoma
-
10.1158/1078-0432.CCR-08-2929, 19509163
-
Huang KH, Huang SF, Chen IH, Liao CT, Wang HM, Hsieh LL. Methylation of RASSF1A, RASSF2A, and HIN-1 is associated with poor outcome after radiotherapy, but not surgery, in oral squamous cell carcinoma. Clin Cancer Res 2009, 15:4174-4180. 10.1158/1078-0432.CCR-08-2929, 19509163.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4174-4180
-
-
Huang, K.H.1
Huang, S.F.2
Chen, I.H.3
Liao, C.T.4
Wang, H.M.5
Hsieh, L.L.6
-
43
-
-
59849104816
-
ARHI, As a Novel Suppressor of Cell Growth and Downregulated in Human Hepatocellular Carcinoma, Could Contribute to Hepatocarcinogenesis
-
10.1002/mc.20461, 18612997
-
Huang J, Lin Y, Li LH, Qing D, Teng XM, Zhang YL, Hu X, Hu YJ, Yang PY, Han ZG. ARHI, As a Novel Suppressor of Cell Growth and Downregulated in Human Hepatocellular Carcinoma, Could Contribute to Hepatocarcinogenesis. Molecular Carcinogenesis 2009, 48:130-140. 10.1002/mc.20461, 18612997.
-
(2009)
Molecular Carcinogenesis
, vol.48
, pp. 130-140
-
-
Huang, J.1
Lin, Y.2
Li, L.H.3
Qing, D.4
Teng, X.M.5
Zhang, Y.L.6
Hu, X.7
Hu, Y.J.8
Yang, P.Y.9
Han, Z.G.10
-
44
-
-
23044464236
-
Extensive modulation of a set of microRNAs in primary glioblastoma
-
10.1016/j.bbrc.2005.07.030, 16039986
-
Ciafre SA, Galardi S, Mangiola A, Ferracin M, Liu CG, Sabatino G, Negrini M, Maira G, Croce CM, Farace MG. Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun 2005, 334:1351-1358. 10.1016/j.bbrc.2005.07.030, 16039986.
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 1351-1358
-
-
Ciafre, S.A.1
Galardi, S.2
Mangiola, A.3
Ferracin, M.4
Liu, C.G.5
Sabatino, G.6
Negrini, M.7
Maira, G.8
Croce, C.M.9
Farace, M.G.10
-
45
-
-
48949116262
-
MiR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
-
2645429, 19087254
-
Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James D, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla1 A, Hodgson JG. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. Bmc Medicine 2008, 6:-. 2645429, 19087254.
-
(2008)
Bmc Medicine
, vol.6
-
-
Silber, J.1
Lim, D.A.2
Petritsch, C.3
Persson, A.I.4
Maunakea, A.K.5
Yu, M.6
Vandenberg, S.R.7
Ginzinger, D.G.8
James, D.9
Costello, J.F.10
Bergers, G.11
Weiss, W.A.12
Alvarez-Buylla1, A.13
Hodgson, J.G.14
-
46
-
-
0027276536
-
Frequent loss of heterozygosity on chromosome 22 in hepatocellular carcinoma
-
10.1002/hep.1840170508, 8387946
-
Takahashi K, Kudo J, Ishibashi H, Hirata Y, Niho Y. Frequent loss of heterozygosity on chromosome 22 in hepatocellular carcinoma. Hepatology 1993, 17:794-799. 10.1002/hep.1840170508, 8387946.
-
(1993)
Hepatology
, vol.17
, pp. 794-799
-
-
Takahashi, K.1
Kudo, J.2
Ishibashi, H.3
Hirata, Y.4
Niho, Y.5
-
47
-
-
26044431923
-
Loss of heterozygosity on chromosome 22 in sporadic schwannoma and its relation to the proliferation of tumor cells
-
Bian LG, Sun QF, Tirakotai W, Zhao WG, Shen JK, Luo QZ, Bertalanffy H. Loss of heterozygosity on chromosome 22 in sporadic schwannoma and its relation to the proliferation of tumor cells. Chin Med J (Engl) 2005, 118:1517-1524.
-
(2005)
Chin Med J (Engl)
, vol.118
, pp. 1517-1524
-
-
Bian, L.G.1
Sun, Q.F.2
Tirakotai, W.3
Zhao, W.G.4
Shen, J.K.5
Luo, Q.Z.6
Bertalanffy, H.7
-
48
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
10.1016/S0092-8674(03)01018-3, 14697198
-
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell 2003, 115:787-798. 10.1016/S0092-8674(03)01018-3, 14697198.
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
49
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
10.1038/72785, 10655057
-
Costello JF, Fruhwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomaki P, Lang JC, Schuller DE, Yu L, Bloomfield CD, Caligiuri MA, Yates A, Nishikawa R, Huang HS, Petrelli NJ, Zhang X, O'Dorisio MS, Held WA, Cavenee WK, Plass C. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nature Genetics 2000, 24:132-138. 10.1038/72785, 10655057.
-
(2000)
Nature Genetics
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
Wright, F.A.7
Feramisco, J.D.8
Peltomaki, P.9
Lang, J.C.10
Schuller, D.E.11
Yu, L.12
Bloomfield, C.D.13
Caligiuri, M.A.14
Yates, A.15
Nishikawa, R.16
Huang, H.S.17
Petrelli, N.J.18
Zhang, X.19
O'Dorisio, M.S.20
Held, W.A.21
Cavenee, W.K.22
Plass, C.23
more..
-
50
-
-
34047274820
-
Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemia
-
10.1158/0008-5472.CAN-06-3993, 17363581
-
Taylor KH, Pena-Hernandez KE, Davis JW, Arthur GL, Duff DJ, Shi HD, Rahmatpanah FB, Sjahputera O, Caldwell CW. Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemia. Cancer Research 2007, 67:2617-2625. 10.1158/0008-5472.CAN-06-3993, 17363581.
-
(2007)
Cancer Research
, vol.67
, pp. 2617-2625
-
-
Taylor, K.H.1
Pena-Hernandez, K.E.2
Davis, J.W.3
Arthur, G.L.4
Duff, D.J.5
Shi, H.D.6
Rahmatpanah, F.B.7
Sjahputera, O.8
Caldwell, C.W.9
-
51
-
-
35548954628
-
Methylation-associated PHOX2B gene silencing is a rare event in human neuroblastoma
-
10.1016/j.ejca.2007.07.016, 17765533
-
de Pontual L, Trochet D, Bourdeaut F, Thomas S, Etchevers H, Chompret A, Minard V, Valteau D, Brugieres L, Munnich A, Delattreb O, Lyonneta S, Janoueix-Leroseyb I, Amiel J. Methylation-associated PHOX2B gene silencing is a rare event in human neuroblastoma. European Journal of Cancer 2007, 43:2366-2372. 10.1016/j.ejca.2007.07.016, 17765533.
-
(2007)
European Journal of Cancer
, vol.43
, pp. 2366-2372
-
-
de Pontual, L.1
Trochet, D.2
Bourdeaut, F.3
Thomas, S.4
Etchevers, H.5
Chompret, A.6
Minard, V.7
Valteau, D.8
Brugieres, L.9
Munnich, A.10
Delattreb, O.11
Lyonneta, S.12
Janoueix-Leroseyb, I.13
Amiel, J.14
-
52
-
-
33748108547
-
A genome-wide search identifies epigenetic silencing of Somatostatin, Tachykinin-1, and 5 other genes in colon cancer. (vol 131, pg 797, 2006)
-
Mori Y, Cai K, Cheng Y, Wang S, Paun B, Hamilton JP, Jin Z, Sato F, Berki AT, Kan T, Ito T, Mantzur C, Abraham JM, Meltzer SJ. A genome-wide search identifies epigenetic silencing of Somatostatin, Tachykinin-1, and 5 other genes in colon cancer. (vol 131, pg 797, 2006). Gastroenterology 2006, 131:1659-1659.
-
(2006)
Gastroenterology
, vol.131
, pp. 1659-1659
-
-
Mori, Y.1
Cai, K.2
Cheng, Y.3
Wang, S.4
Paun, B.5
Hamilton, J.P.6
Jin, Z.7
Sato, F.8
Berki, A.T.9
Kan, T.10
Ito, T.11
Mantzur, C.12
Abraham, J.M.13
Meltzer, S.J.14
-
53
-
-
58249133452
-
Discovery of DNA methylation markers in cervical cancer using relaxation ranking
-
2632664, 19114010
-
Ongenaert M, Wisman GBA, Volders HH, Koning AJ, van der Zee AGJ, van Criekinge W, Schuuring E. Discovery of DNA methylation markers in cervical cancer using relaxation ranking. Bmc Medical Genomics 2008, 1:-. 2632664, 19114010.
-
(2008)
Bmc Medical Genomics
, vol.1
-
-
Ongenaert, M.1
Wisman, G.B.A.2
Volders, H.H.3
Koning, A.J.4
van der Zee, A.G.J.5
van Criekinge, W.6
Schuuring, E.7
-
54
-
-
70349742486
-
DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer
-
10.1158/0008-5472.CAN-09-0116, 2745494, 19723660
-
Jin B, Yao B, Li JL, Fields CR, Delmas AL, Liu C, Robertson KD. DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer. Cancer Res 2009, 69:7412-7421. 10.1158/0008-5472.CAN-09-0116, 2745494, 19723660.
-
(2009)
Cancer Res
, vol.69
, pp. 7412-7421
-
-
Jin, B.1
Yao, B.2
Li, J.L.3
Fields, C.R.4
Delmas, A.L.5
Liu, C.6
Robertson, K.D.7
-
55
-
-
29644440839
-
Deletion of the ANKRD15 gene at 9p24.3 causes parent-of-origin-dependent inheritance of familial cerebral palsy
-
10.1093/hmg/ddi415, 16301218
-
Lerer I, Sagi M, Meiner V, Cohen T, Zlotogora J, Abeliovich D. Deletion of the ANKRD15 gene at 9p24.3 causes parent-of-origin-dependent inheritance of familial cerebral palsy. Human Molecular Genetics 2005, 14:3911-3920. 10.1093/hmg/ddi415, 16301218.
-
(2005)
Human Molecular Genetics
, vol.14
, pp. 3911-3920
-
-
Lerer, I.1
Sagi, M.2
Meiner, V.3
Cohen, T.4
Zlotogora, J.5
Abeliovich, D.6
-
56
-
-
38649094308
-
GAD1 mRNA Expression and DNA Methylation in Prefrontal Cortex of Subjects with Schizophrenia
-
2267039, 18338032
-
Huang HS, Akbarian S. GAD1 mRNA Expression and DNA Methylation in Prefrontal Cortex of Subjects with Schizophrenia. Plos One 2007, 2:-. 2267039, 18338032.
-
(2007)
Plos One
, vol.2
-
-
Huang, H.S.1
Akbarian, S.2
-
57
-
-
61849100510
-
Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis
-
10.1007/s00702-008-0156-y, 19034380
-
Martins-de-Souza D, Gattaz WF, Schmitt A, Rewerts C, Marangoni S, Novello JC, Maccarrone G, Turck CW, Dias E. Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis. Journal of Neural Transmission 2009, 116:275-289. 10.1007/s00702-008-0156-y, 19034380.
-
(2009)
Journal of Neural Transmission
, vol.116
, pp. 275-289
-
-
Martins-de-Souza, D.1
Gattaz, W.F.2
Schmitt, A.3
Rewerts, C.4
Marangoni, S.5
Novello, J.C.6
Maccarrone, G.7
Turck, C.W.8
Dias, E.9
-
58
-
-
75449099529
-
An 8-gene signature, including methylated and down-regulated glutathione peroxidase 3, of gastric cancer
-
Zhang X, Yang JJ, Kim YS, Kim KY, Ahn WS, Yang S. An 8-gene signature, including methylated and down-regulated glutathione peroxidase 3, of gastric cancer. International Journal of Oncology 2010, 36:405-414.
-
(2010)
International Journal of Oncology
, vol.36
, pp. 405-414
-
-
Zhang, X.1
Yang, J.J.2
Kim, Y.S.3
Kim, K.Y.4
Ahn, W.S.5
Yang, S.6
-
59
-
-
0037439697
-
The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas
-
Laflamme C, Filion C, Bridge JA, Ladanyi M, Goldring MB, Labelle Y. The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas. Cancer Research 2003, 63:449-454.
-
(2003)
Cancer Research
, vol.63
, pp. 449-454
-
-
Laflamme, C.1
Filion, C.2
Bridge, J.A.3
Ladanyi, M.4
Goldring, M.B.5
Labelle, Y.6
-
60
-
-
0035839057
-
The role of DNA methylation in mammalian epigenetics
-
10.1126/science.1063852, 11498573
-
Jones PA, Takai D. The role of DNA methylation in mammalian epigenetics. Science 2001, 293:1068-1070. 10.1126/science.1063852, 11498573.
-
(2001)
Science
, vol.293
, pp. 1068-1070
-
-
Jones, P.A.1
Takai, D.2
-
61
-
-
68949198148
-
MiR-107 and MiR-185 Can Induce Cell Cycle Arrest in Human Non Small Cell Lung Cancer Cell Lines
-
2809086, 20107496
-
Takahashi Y, Forrest ARR, Maeno E, Hashimoto T, Daub CO, Yasuda J. MiR-107 and MiR-185 Can Induce Cell Cycle Arrest in Human Non Small Cell Lung Cancer Cell Lines. Plos One 2009, 4:-. 2809086, 20107496.
-
(2009)
Plos One
, vol.4
-
-
Takahashi, Y.1
Forrest, A.R.R.2
Maeno, E.3
Hashimoto, T.4
Daub, C.O.5
Yasuda, J.6
|