High levels of human recombinant cyclooxygenase-1 expression in mammalian cells using a novel gene amplification method

Protein Expression and Purification

Volumn 80, Issue 1, 2011, Pages 41-46

  Yoshimura, Hiromitsu ^a   Sekine, Shingo ^a   Adachi, Hisashi ^a   Uematsu, Yoshikatsu ^a   Mitani, Akiko ^a   Futaki, Nobuko ^a   Shimizu, Noriaki ^b  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

dhfr MTX gene amplification; Human COX 1; IR MAR gene amplification; Mammalian cells; Recombinant protein production

Indexed keywords

CYCLOOXYGENASE 1; INDOMETACIN; MESSENGER RNA; PROSTAGLANDIN SYNTHASE INHIBITOR; RECOMBINANT PROTEIN;

ARTICLE; CELL LINE; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; PLASMID;

CELL LINE; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; GENE AMPLIFICATION; GENE EXPRESSION; HUMANS; INDOMETHACIN; PLASMIDS; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSFECTION;

MAMMALIA;

EID: 80053310869     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pep.2011.05.009     Document Type: Article

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