Ca2+ sensitization of cardiac myofilament proteins contributes to exercise training-enhanced myocardial function in a porcine model of chronic occlusion

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 301, Issue 4, 2011, Pages

  Sarin, Vandana ^b   Muthuchamy, Mariappan ^c,d   Heaps, Cristine L ^a,b,d  

^a Michael E DeBakey Institute for Comparative Cardiovascular Science and Biomedical Devices   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c Department of Systems Biology and Translational Medicine ^*  (United States)

^d TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

Calcium sensitivity; Coronary artery disease; Ischemic heart disease; Myocardial function

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; CALCIUM ION; CITRATE SYNTHASE; DOBUTAMINE; MYOSIN BINDING PROTEIN C; TROPONIN I; TROPONIN T; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM; PHOSPHOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM CELL LEVEL; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; CORONARY ARTERY CIRCUMFLEX BRANCH; DELTOID MUSCLE; ENZYME ACTIVITY; EXERCISE; FEMALE; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE; HEART MUSCLE CONTRACTILITY; MYOFILAMENT; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; TREADMILL EXERCISE; TRICEPS BRACHII MUSCLE; ANIMAL; COLLATERAL CIRCULATION; DRUG EFFECT; ELECTROSTIMULATION; HEART FUNCTION TEST; HEART MUSCLE CELL; IN VITRO STUDY; METABOLISM; MUSCLE FIBRIL; PATHOPHYSIOLOGY; PHYSIOLOGY; SWINE; WESTERN BLOTTING;

ADRENERGIC BETA-AGONISTS; ANIMALS; BLOTTING, WESTERN; CALCIUM; COLLATERAL CIRCULATION; CORONARY OCCLUSION; DOBUTAMINE; ELECTRIC STIMULATION; FEMALE; HEART FUNCTION TESTS; MYOCARDIUM; MYOCYTES, CARDIAC; MYOFIBRILS; PHOSPHOPROTEINS; PHYSICAL CONDITIONING, ANIMAL; SWINE;

EID: 80053291141     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00294.2011     Document Type: Article

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