Performance of THz fiber-scanning near-field microscopy to diagnose breast tumors

Optics Express

Volumn 19, Issue 20, 2011, Pages 19523-19531

  Chen, Hua ^a   Wen Jeng Lee, ^a,b   Huang, Hsin Yi ^b   Chiu, Chui Min ^a   Tsai, Yuan Fu ^a   Tseng, Tzu Fang ^a   Lu, Jen Tang ^a   Lai, Wei Ling ^a   Sun, Chi Kuang ^a,c  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c INSTITUTE OF PHYSICS   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

HISTOLOGY; SCANNING; TRANSPLANTATION (SURGICAL);

BREAST CONSERVING SURGERY; BREAST TISSUES; BREAST TUMOR; MEAN AGES; NEAR FIELD MICROSCOPY; NORMAL TISSUE; SURGICAL PROCEDURES; TERAHERTZ;

TUMORS;

ADULT; AGED; ARTICLE; ATOMIC FORCE MICROSCOPY; BREAST; BREAST TUMOR; COMPARATIVE STUDY; FEMALE; HUMAN; METHODOLOGY; MIDDLE AGED; PATHOLOGY; TERAHERTZ SPECTROSCOPY;

ADULT; AGED; BREAST; BREAST NEOPLASMS; FEMALE; HUMANS; MICROSCOPY, ATOMIC FORCE; MIDDLE AGED; TERAHERTZ SPECTROSCOPY;

EID: 80053284676     PISSN: None     EISSN: 10944087     Source Type: Journal    
DOI: 10.1364/OE.19.019523     Document Type: Article

References (23)

1. D. Abbott and X. C. Zhang, "Scanning the issue: T-ray imaging, sensing, and detection," Proc. IEEE 95(8), 1509-1513 (2007).
2. B. Ferguson, S. Wang, D. Gray, D. Abbott, and X. C. Zhang, "Identification of biological tissue using chirped probe THz imaging," Microelectron. J. 33(12), 1043-1051 (2002). (Pubitemid 35433510)
3. A. J. Fitzgerald, B. E. Cole, and P. F. Taday, "Nondestructive analysis of tablet coating thicknesses using terahertz pulsed imaging," J. Pharm. Sci. 94(1), 177-183 (2005). (Pubitemid 40116381)
4. T. Löffler, T. Bauer, K. Siebert, H. Roskos, A. Fitzgerald, and S. Czasch, "Terahertz dark-field imaging of biomedical tissue," Opt. Express 9(12), 616-621 (2001), http://www.opticsinfobase.org/oe/abstract.cfm? URI=oe-9-12-616.
5. R. M. Woodward, B. E. Cole, V. P. Wallace, R. J. Pye, D. D. Arnone, E. H. Linfield, and M. Pepper, "Terahertz pulse imaging in reflection geometry of human skin cancer and skin tissue," Phys. Med. Biol. 47(21), 3853-3863 (2002). (Pubitemid 35363536)
6. A. G. Markelz, A. Roitberg, and E. J. Heilweil, "Pulsed terahertz spectroscopy of DNA, bovine serum albumin and collagen between 0.1 and 2.0 THz," Chem. Phys. Lett. 320(1-2), 42-48 (2000).
7. M. Brucherseifer, M. Nagel, P. Haring Bolivar, H. Kurz, A. Bosserhoff, and R. Büttner, "Label-free probing of the binding state of DNA by time-domain terahertz sensing," Appl. Phys. Lett. 77(24), 4049-4051 (2000).
8. K. Kawase, Y. Ogawa, Y. Watanabe, and H. Inoue, "Non-destructive terahertz imaging of illicit drugs using spectral fingerprints," Opt. Express 11(20), 2549-2554 (2003), http://www.opticsinfobase.org/oe/abstract.cfm? URI=oe-11-20-2549.
9. M. Yamaguchi, F. Miyamaru, K. Yamamoto, M. Tani, and M. Hangyo, "Terahertz absorption spectra of L-, D-, and D L-alanine and their application to determination of enantiometric composition," Appl. Phys. Lett. 86(5), 053903 (2005).
10. X. C. Zhang, "Terahertz wave imaging: horizons and hurdles," Phys. Med. Biol. 47(21), 3667-3677 (2002).
11. D. Crawley, C. Longbottom, V. P. Wallace, B. Cole, D. Arnone, and M. Pepper, "Three-dimensional terahertz pulse imaging of dental tissue," J. Biomed. Opt. 8(2), 303-307 (2003).
12. D. A. Crawley, C. Longbottom, B. E. Cole, C. M. Ciesla, D. Arnone, V. P. Wallace, and M. Pepper, "Terahertz pulse imaging: a pilot study of potential applications in dentistry," Caries Res. 37(5), 352-359 (2003). (Pubitemid 37108899)
13. A. Jemal, R. Siegel, J. Xu, and E. Ward, "Cancer statistics, 2010," CA Cancer J. Clin. 60(5), 277-300 (2010).
14. A. J. Fitzgerald, V. P. Wallace, M. Jimenez-Linan, L. Bobrow, R. J. Pye, A. D. Purushotham, and D. D. Arnone, "Terahertz pulsed imaging of human breast tumors," Radiology 239(2), 533-540 (2006).
15. P. C. Ashworth, E. Pickwell-MacPherson, S. E. Pinder, E. Provenzano, A. D. Purushotham, M. Pepper, and V. P. Wallace, "Terahertz spectroscopy of breast tumors," in Proceedings of IEEE Conference on Infrared and Millimeter Waves and Terahertz Electronics (Cardiff, UK, 2007), pp. 603-605.
16. P. C. Ashworth, E. Pickwell-MacPherson, E. Provenzano, S. E. Pinder, A. D. Purushotham, M. Pepper, and V. P. Wallace, "Terahertz pulsed spectroscopy of freshly excised human breast cancer," Opt. Express 17(15), 12444-12454 (2009), http://www.opticsinfobase.org/abstract.cfm?URI=oe-17-15- 12444.
17. S. Sy, S. Y. Huang, Y.-X. J. Wang, J. Yu, A. T. Ahuja, Y.-T. Zhang, and E. Pickwell-MacPherson, "Terahertz spectroscopy of liver cirrhosis: investigating the origin of contrast," Phys. Med. Biol. 55(24), 7587-7596 (2010).
18. C. M. Chiu, H. W. Chen, Y. R. Huang, Y. J. Hwang, W. J. Lee, H. Y. Huang, and C. K. Sun, "All-terahertz fiber-scanning near-field microscopy," Opt. Lett. 34(7), 1084-1086 (2008), http://www.opticsinfobase.org/abstract.cfm? URI=ol-34-7-1084.
19. L. J. Chen, H. W. Chen, T. F. Kao, J. Y. Lu, and C. K. Sun, "Low-loss subwavelength plastic fiber for terahertz waveguiding," Opt. Lett. 31(3), 308-310 (2006), http://www.opticsinfobase.org/abstract.cfm?URI=ol- 31-3-308.
20. H.-W. Chen, Y.-T. Li, C.-L. Pan, J.-L. Kuo, J.-Y. Lu, L.-J. Chen, and C.-K. Sun, "Investigation on spectral loss characteristics of subwavelength terahertz fibers," Opt. Lett. 32(9), 1017-1019 (2007), http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-9-1017. (Pubitemid 46557604)
21. J. E. Carlstrom, L. R. Plambeck, and D. D. Thornton, "A continuously tunable 65-115GHz Gunn oscillator," IEEE Trans. Microw. Theory Tech. 33(7), 610-619 (1985). (Pubitemid 15597226)
22. H. Eisele, A. Rydberg, and G. I. Haddad, "Recent advances in the performance of InP Gunn devices and GaAs TUNNETT diodes for the 100-300GHz frequency range and above," IEEE Trans. Microw. Theory Tech. 48(4), 626-631 (2000).
23. G. M. Png, J. W. Choi, B. W. Ng, S. P. Mickan, D. Abbott, and X. C. Zhang, "The impact of hydration changes in fresh bio-tissue on THz spectroscopic measurements," Phys. Med. Biol. 53(13), 3501-3517 (2008). (Pubitemid 352020036)