Intravenous AICAR during hyperinsulinemia induces systemic hemodynamic changes but has no local metabolic effect

Journal of Clinical Pharmacology

Volumn 51, Issue 10, 2011, Pages 1449-1458

  Bosselaar, Marlies ^a   Smits, Paul ^a   Van Loon, Luc J C ^b   Tack, Cees J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

AICAR; euglycemic hyperinsulinemic clamp; forearm blood flow; forearm glucose uptake; glucose infusion rate

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE;

ADULT; ARTICLE; CONTROLLED STUDY; DIZZINESS; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG MECHANISM; DRUG UPTAKE; FEMALE; FOREARM; GLUCOSE TRANSPORT; HEMODYNAMICS; HUMAN; HUMAN EXPERIMENT; HYPERINSULINEMIA; MALE; NAUSEA; NORMAL HUMAN; PALLOR; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINGLE BLIND PROCEDURE; SWEATING; SYNCOPE; UNCONSCIOUSNESS; VASODILATATION; VOMITING;

AMINOIMIDAZOLE CARBOXAMIDE; BLOOD GLUCOSE; BLOOD PRESSURE; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; HEART RATE; HEMODYNAMICS; HUMANS; HYPERINSULINISM; MUSCLE, SKELETAL; RIBONUCLEOTIDES;

EID: 80053257228     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270010382912     Document Type: Article

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