-
1
-
-
67649429268
-
Impact of cholesterol metabolism and the LXRalpha-SREBP-1c pathway on nonalcoholic fatty liver disease
-
Nakamuta M, Fujino T, Yada R, Yada M, Yasutake K, Yoshimoto T, Harada N, Higuchi N, Kato M, Kohjima M, Taketomi A, Maehara Y, Nakashima M, Kotoh K, Enjoji M. Impact of cholesterol metabolism and the LXRalpha-SREBP-1c pathway on nonalcoholic fatty liver disease. Int J Mol Med. 2009; 23(5): 603-608.
-
(2009)
Int J Mol Med
, vol.23
, Issue.5
, pp. 603-608
-
-
Nakamuta, M.1
Fujino, T.2
Yada, R.3
Yada, M.4
Yasutake, K.5
Yoshimoto, T.6
Harada, N.7
Higuchi, N.8
Kato, M.9
Kohjima, M.10
Taketomi, A.11
Maehara, Y.12
Nakashima, M.13
Kotoh, K.14
Enjoji, M.15
-
2
-
-
53349153430
-
Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
-
Higuchi N, Kato M, Shundo Y, Tajiri H, Tanaka M, Yamashita N, Kohjima M, Kotoh K, Nakamuta M, Takayanagi R, Enjoji M. Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease. Hepatol Res. 2008; 38(11): 1122-1129.
-
(2008)
Hepatol Res
, vol.38
, Issue.11
, pp. 1122-1129
-
-
Higuchi, N.1
Kato, M.2
Shundo, Y.3
Tajiri, H.4
Tanaka, M.5
Yamashita, N.6
Kohjima, M.7
Kotoh, K.8
Nakamuta, M.9
Takayanagi, R.10
Enjoji, M.11
-
3
-
-
77949916811
-
Enhanced steatosis by nuclear receptor ligands: A study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile
-
Moya M, Gomez-Lechon MJ, Castell JV, Jover R. Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile. Chem Biol Interact. 2010; 184(3): 376-387.
-
(2010)
Chem Biol Interact
, vol.184
, Issue.3
, pp. 376-387
-
-
Moya, M.1
Gomez-Lechon, M.J.2
Castell, J.V.3
Jover, R.4
-
4
-
-
80053210175
-
Effect of Jiangzhi granulas on serum leptin and liver leptin receptor mRNA of nonalcoholic fatty liver disease rat
-
Zheng PY, Ma ZS, Liu T, Xing LJ, Ji G. Effect of Jiangzhi granulas on serum leptin and liver leptin receptor mRNA of nonalcoholic fatty liver disease rat. Zhongguo Zhong Yi Yao Xin Xi Za Zhi. 2008; 15 (6): 36-38.
-
(2008)
Zhongguo Zhong Yi Yao Xin Xi Za Zhi
, vol.15
, Issue.6
, pp. 36-38
-
-
Zheng, P.Y.1
Ma, Z.S.2
Liu, T.3
Xing, L.J.4
Ji, G.5
-
5
-
-
84871389716
-
Effect of Jiangzhi granula on leptin and leptin receptor of hypothalamus in rats with nonalcoholic liver disease
-
Zhang L, Liu T, Wang M, Xing LJ, Ji G, Zheng PY. Effect of Jiangzhi granula on leptin and leptin receptor of hypothalamus in rats with nonalcoholic liver disease. Zhong Xi Yi Jie He Gan Bing Za Zhi. 2009; 19(2) 8891.
-
(2009)
Zhong Xi Yi Jie He Gan Bing Za Zhi
, vol.19
, Issue.2
, pp. 8891
-
-
Zhang, L.1
Liu, T.2
Wang, M.3
Xing, L.J.4
Ji, G.5
Zheng, P.Y.6
-
6
-
-
69749107541
-
Effect of Jiangzhi granule on STAT3 expression in hypothalamus of rats with nonalcoholic fatty liver disease
-
Zheng PY, Zhang L, Liu T, Wang M, Xing LJ, Ji G. Effect of Jiangzhi granule on STAT3 expression in hypothalamus of rats with nonalcoholic fatty liver disease. Shi Jie Hua Ren Xiao Hua Za Zhi. 2009; 17 (8): 753-757.
-
(2009)
Shi Jie Hua Ren Xiao Hua Za Zhi
, vol.17
, Issue.8
, pp. 753-757
-
-
Zheng, P.Y.1
Zhang, L.2
Liu, T.3
Wang, M.4
Xing, L.J.5
Ji, G.6
-
7
-
-
0036234962
-
Rat model of nonalcoholic steatohepatitis with fibrosis by a fat-rich diet
-
Xu ZJ, Fan JG, Wang GL, Ding XD, Tian LY, Zheng XY. Rat model of nonalcoholic steatohepatitis with fibrosis by a fat-rich diet. Shi Jie Hua Ren Xiao Hua Za Zhi. 2002; 10 (4): 392-396.
-
(2002)
Shi Jie Hua Ren Xiao Hua Za Zhi
, vol.10
, Issue.4
, pp. 392-396
-
-
Xu, Z.J.1
Fan, J.G.2
Wang, G.L.3
Ding, X.D.4
Tian, L.Y.5
Zheng, X.Y.6
-
8
-
-
30944469157
-
Non-alcoholic fatty liver disease and metabolic syndrome: What we know and what we don't know
-
Akbar DH, Kawther AH. Non-alcoholic fatty liver disease and metabolic syndrome: what we know and what we don't know. Med Sci Monit. 2006; 12(1): RA23-RA26.
-
(2006)
Med Sci Monit
, vol.12
, Issue.1
-
-
Akbar, D.H.1
Kawther, A.H.2
-
9
-
-
33847053864
-
-
Beijing: People's Medical Publishing House
-
Fan JG, Zeng MD. Fatty liver diseases. Beijing: People's Medical Publishing House. 2005: 118.
-
(2005)
Fatty Liver Diseases
, pp. 118
-
-
Fan, J.G.1
Zeng, M.D.2
-
11
-
-
0032516081
-
ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand
-
Kim JB, Wright HM, Wright M, Spiegelman BM. ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand. Proc Natl Acad Sci USA. 1998; 95(8): 4333-4337.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.8
, pp. 4333-4337
-
-
Kim, J.B.1
Wright, H.M.2
Wright, M.3
Spiegelman, B.M.4
-
12
-
-
0034693259
-
Sterol regulatory element-binding proteins (SREBPs): Key regulators of nutritional homeostasis and insulin action
-
Osborne TF. Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action. J Biol Chem. 2000; 275(42): 32379-32382.
-
(2000)
J Biol Chem
, vol.275
, Issue.42
, pp. 32379-32382
-
-
Osborne, T.F.1
-
13
-
-
0035860743
-
Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription
-
Chakravarty K, Leahy P, Becard D, Hakimi P, Foretz M, Ferre P, Foufelle F, Hanson RW. Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription. J Biol Chem. 2001; 276 (37): 34816-34823.
-
(2001)
J Biol Chem
, vol.276
, Issue.37
, pp. 34816-34823
-
-
Chakravarty, K.1
Leahy, P.2
Becard, D.3
Hakimi, P.4
Foretz, M.5
Ferre, P.6
Foufelle, F.7
Hanson, R.W.8
-
14
-
-
0033607176
-
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
-
Foretz M, Guichard C, Ferre P, Foufelle F. Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci USA. 1999; 96(22): 12737-12742.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.22
, pp. 12737-12742
-
-
Foretz, M.1
Guichard, C.2
Ferre, P.3
Foufelle, F.4
-
15
-
-
58449087109
-
SREBPs: Novel aspects of SREBPs in the regulation of lipid synthesis
-
Shimano H. SREBPs: novel aspects of SREBPs in the regulation of lipid synthesis. FEBS J. 2009; 276 (3): 615.
-
(2009)
FEBS J
, vol.276
, Issue.3
, pp. 615
-
-
Shimano, H.1
-
16
-
-
2342536384
-
Molecular regulation of SREBP function: The Insig-SCAP connection and isoformspecific modulation of lipid synthesis
-
McPherson R, Gauthier A. Molecular regulation of SREBP function: the Insig-SCAP connection and isoformspecific modulation of lipid synthesis. Biochem Cell Biol. 2004; 82(1): 201-211.
-
(2004)
Biochem Cell Biol
, vol.82
, Issue.1
, pp. 201-211
-
-
McPherson, R.1
Gauthier, A.2
-
17
-
-
33644651160
-
Liver X receptors as integrators of metabolic and inflammatory signaling
-
Zelcer N, Tontonoz P. Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest. 2006; 116(3): 607-614.
-
(2006)
J Clin Invest
, vol.116
, Issue.3
, pp. 607-614
-
-
Zelcer, N.1
Tontonoz, P.2
-
18
-
-
23444431623
-
Retinoid x receptor heterodimers in the metabolic syndrome
-
Shulman AI, Mangelsdorf DJ. Retinoid x receptor heterodimers in the metabolic syndrome. N Engl J Med. 2005; 353(6): 604-615.
-
(2005)
N Engl J Med
, vol.353
, Issue.6
, pp. 604-615
-
-
Shulman, A.I.1
Mangelsdorf, D.J.2
-
19
-
-
33847006599
-
The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR
-
Cha JY, Repa JJ. The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR. J Biol Chem. 2007; 282(1): 743-751.
-
(2007)
J Biol Chem
, vol.282
, Issue.1
, pp. 743-751
-
-
Cha, J.Y.1
Repa, J.J.2
-
20
-
-
38649096259
-
Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis
-
Zhou J, Febbraio M, Wada T, Zhai Y, Kuruba R, He J, Lee JH, Khadem S, Ren S, Li S, Silverstein RL, Xie W. Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. Gastroenterology. 2008; 134(2): 556-567.
-
(2008)
Gastroenterology
, vol.134
, Issue.2
, pp. 556-567
-
-
Zhou, J.1
Febbraio, M.2
Wada, T.3
Zhai, Y.4
Kuruba, R.5
He, J.6
Lee, J.H.7
Khadem, S.8
Ren, S.9
Li, S.10
Silverstein, R.L.11
Xie, W.12
-
21
-
-
0035101931
-
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice
-
Alberti S, Schuster G, Parini P, Feltkamp D, Diczfalusy U, Rudling M, Angelin B, Bjorkhem I, Pettersson S, Gustafsson JA. Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice. J Clin Invest. 2001; 107(5): 565-573.
-
(2001)
J Clin Invest
, vol.107
, Issue.5
, pp. 565-573
-
-
Alberti, S.1
Schuster, G.2
Parini, P.3
Feltkamp, D.4
Diczfalusy, U.5
Rudling, M.6
Angelin, B.7
Bjorkhem, I.8
Pettersson, S.9
Gustafsson, J.A.10
-
22
-
-
12844271136
-
Differential regulation of sterol regulatory element-binding protein 1c transcriptional activity by insulin and liver X receptor during liver development
-
Bobard A, Hainault I, Ferre P, Foufelle F, Bossard P. Differential regulation of sterol regulatory element-binding protein 1c transcriptional activity by insulin and liver X receptor during liver development. J Biol Chem. 2005; 280(1): 199-206.
-
(2005)
J Biol Chem
, vol.280
, Issue.1
, pp. 199-206
-
-
Bobard, A.1
Hainault, I.2
Ferre, P.3
Foufelle, F.4
Bossard, P.5
-
23
-
-
0037088683
-
Diminished hepatic response to fasting/ refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c
-
Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS. Diminished hepatic response to fasting/ refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J Biol Chem. 2002; 277(11): 9520-9528.
-
(2002)
J Biol Chem
, vol.277
, Issue.11
, pp. 9520-9528
-
-
Liang, G.1
Yang, J.2
Horton, J.D.3
Hammer, R.E.4
Goldstein, J.L.5
Brown, M.S.6
-
24
-
-
0036139677
-
Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease
-
Zoccali C, Mallamaci F, Tripepi G, Benedetto FA, Cutrupi S, Parlongo S, Malatino LS, Bonanno G, Seminara G, Rapisarda F, Fatuzzo P, Buemi M, Nicocia G, Tanaka S, Ouchi N, Kihara S, Funahashi T, Matsuzawa Y. Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease. J Am Soc Nephrol. 2002; 13(1): 134-141.
-
(2002)
J Am Soc Nephrol
, vol.13
, Issue.1
, pp. 134-141
-
-
Zoccali, C.1
Mallamaci, F.2
Tripepi, G.3
Benedetto, F.A.4
Cutrupi, S.5
Parlongo, S.6
Malatino, L.S.7
Bonanno, G.8
Seminara, G.9
Rapisarda, F.10
Fatuzzo, P.11
Buemi, M.12
Nicocia, G.13
Tanaka, S.14
Ouchi, N.15
Kihara, S.16
Funahashi, T.17
Matsuzawa, Y.18
-
25
-
-
30444461216
-
Insulin resistance, adiponectin, cytokines in NASH: Which is the best target to treat?
-
Larter CZ, Farrell GC. Insulin resistance, adiponectin, cytokines in NASH: Which is the best target to treat? J Hepatol. 2006; 44(2): 253-261.
-
(2006)
J Hepatol
, vol.44
, Issue.2
, pp. 253-261
-
-
Larter, C.Z.1
Farrell, G.C.2
|