메뉴 건너뛰기




Volumn 33, Issue 11, 2011, Pages 2103-2110

Simplified off-gas analyses in animal cell cultures for process monitoring and control purposes

Author keywords

BlueSens analyzer; Carbon dioxide production rate; CHO cells; Oxygen uptake rate

Indexed keywords

ADVANCED CONTROL; ADVANCED PROCESS CONTROL; BLUESENS ANALYZER; CHO CELL; CONTROL PROCEDURES; LABORATORY SCALE; LOW-COST SENSORS; OFF-GAS ANALYSIS; OXYGEN UPTAKE RATE; PROCESS MONITORING AND CONTROL; QUADRUPOLE MASS SPECTROMETER; REPRODUCIBILITIES; STANDARD EQUIPMENTS;

EID: 80053202599     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-011-0686-5     Document Type: Article
Times cited : (48)

References (11)
  • 1
    • 79951673290 scopus 로고    scopus 로고
    • Increasing batch-to-batch reproducibility of CHO cultures by robust open-loop control
    • Aehle M, Kuprijanov A, Schaepe S, Simutis R, Lübbert A (2011a) Increasing batch-to-batch reproducibility of CHO cultures by robust open-loop control. Cytotechnology 63(1): 41-47.
    • (2011) Cytotechnology , vol.63 , Issue.1 , pp. 41-47
    • Aehle, M.1    Kuprijanov, A.2    Schaepe, S.3    Simutis, R.4    Lübbert, A.5
  • 4
    • 0029635979 scopus 로고
    • On-line gas analysis in animal cell cultivation: II. Methods for oxygen uptake rate estimation and its application to controlled feeding of glutamine
    • Eyer K, Oeggerli A, Heinzle E (1995) On-line gas analysis in animal cell cultivation: II. Methods for oxygen uptake rate estimation and its application to controlled feeding of glutamine. Biotechnol Bioeng 45: 54-62.
    • (1995) Biotechnol Bioeng , vol.45 , pp. 54-62
    • Eyer, K.1    Oeggerli, A.2    Heinzle, E.3
  • 5
    • 84984087831 scopus 로고
    • Automatic analysis of gas exchange in microbial systems
    • Fiechter A, von Meyenburg K (1968) Automatic analysis of gas exchange in microbial systems. Biotechnol Bioeng 10: 535-549.
    • (1968) Biotechnol Bioeng , vol.10 , pp. 535-549
    • Fiechter, A.1    von Meyenburg, K.2
  • 6
    • 0037164169 scopus 로고    scopus 로고
    • Determination of dissolved CO2 concentration and CO2 production rate of mammalian cell suspension culture based on off-gas measurement
    • Frahm B, Blank H-C, Cornand P, Oelßner W, Guth U, Lane P, Munack A, Johannsen K, Pörtner R (2002) Determination of dissolved CO2 concentration and CO2 production rate of mammalian cell suspension culture based on off-gas measurement. J Biotechnol 99: 133-148.
    • (2002) J Biotechnol , vol.99 , pp. 133-148
    • Frahm, B.1    Blank, H.-C.2    Cornand, P.3    Oelßner, W.4    Guth, U.5    Lane, P.6    Munack, A.7    Johannsen, K.8    Pörtner, R.9
  • 8
    • 33847337911 scopus 로고    scopus 로고
    • Improving the batch-to-batch reproducibility of microbial cultures during recombinant protein production by regulation of total carbon dioxide production
    • Jenzsch M, Gnoth S, Kleinschmidt M, Simutis R, Lübbert A (2007) Improving the batch-to-batch reproducibility of microbial cultures during recombinant protein production by regulation of total carbon dioxide production. J Biotechnol 128: 858-867.
    • (2007) J Biotechnol , vol.128 , pp. 858-867
    • Jenzsch, M.1    Gnoth, S.2    Kleinschmidt, M.3    Simutis, R.4    Lübbert, A.5
  • 10
    • 0028979470 scopus 로고
    • On-line gas analysis in animal cell cultivation: I. Control of dissolved oxygen and pH
    • Oeggerli A, Eyer K, Heinzle E (1995) On-line gas analysis in animal cell cultivation: I. Control of dissolved oxygen and pH. Biotechnol Bioeng 45: 42-53.
    • (1995) Biotechnol Bioeng , vol.45 , pp. 42-53
    • Oeggerli, A.1    Eyer, K.2    Heinzle, E.3
  • 11
    • 0027113007 scopus 로고
    • Effect of changes in the pH and carbon dioxide evolution rate on the measured respiratory quotient of fermentations
    • Royce PN (1992) Effect of changes in the pH and carbon dioxide evolution rate on the measured respiratory quotient of fermentations. Biotechnol Bioeng 40: 1129-1138.
    • (1992) Biotechnol Bioeng , vol.40 , pp. 1129-1138
    • Royce, P.N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.