Multiple glycogen-binding sites in eukaryotic glycogen synthase are required for high catalytic efficiency toward glycogen

Journal of Biological Chemistry

Volumn 286, Issue 39, 2011, Pages 33999-34006

  Baskaran, Sulochanadevi ^a,c   Chikwana, Vimbai M ^a   Contreras, Christopher J ^a   Davis, Keri D ^b   Wilson, Wayne A ^b   DePaoli Roach, Anna A ^a   Roach, Peter J ^a   Hurley, Thomas D ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Des Moines University College of Osteopathic Medicine   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; C-TERMINAL DOMAINS; CATALYTIC EFFICIENCIES; DATA SUPPORT; GLUCOSE HOMEOSTASIS; GLYCOGEN SYNTHASE; IN-VITRO; INTER-DOMAIN; N-TERMINAL DOMAINS; RATE-LIMITING ENZYMES; SURFACE SITES; THREE-DIMENSIONAL STRUCTURE; YEAST CELL;

ENZYMES; GLUCOSE; YEAST;

BINDING SITES;

GLYCOGEN; GLYCOGEN SYNTHASE; MALTODEXTRIN;

ARTICLE; BINDING SITE; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME SUBSTRATE; GLYCOGEN BINDING SITE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; YEAST CELL;

BINDING SITES; GLYCOGEN; GLYCOGEN SYNTHASE; MUTATION; OLIGOSACCHARIDES; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA;

EID: 80053177304     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.264531     Document Type: Article

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