Cytokine induction of iNOS and sPLA2 in immortalized astrocytes (DITNC): Response to genistein and pyrrolidine dithiocarbamate

Journal of Interferon and Cytokine Research

Volumn 19, Issue 2, 1999, Pages 121-127

  Li, Wei ^a   Xia, Jinming ^a   Sun, Grace Y ^a  

^a University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; GAMMA INTERFERON; GENISTEIN; INTERLEUKIN 1BETA; LYSINE DERIVATIVE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHOLIPASE A2; PROTEIN TYROSINE KINASE; PYRROLIDINE DITHIOCARBAMATE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; ASTROCYTE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RAT; REACTION ANALYSIS; REACTION TIME; REGULATORY MECHANISM; RNA ANALYSIS; TRANSLATION REGULATION;

ANIMALS; ASTROCYTES; CELL LINE; CELL SURVIVAL; CYTOKINES; ENZYME INHIBITORS; GENISTEIN; INTERFERON-ALPHA; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHOLIPASES A; PYRROLIDINES; RATS; RNA, MESSENGER; THIOCARBAMATES; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0033023856     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999099314261     Document Type: Article

References (33)

1. MURPHY, S., SIMMONS, M.L., AGULLO, L., GARCIA, A., FEINSTEIN, D.L., GALEA, E., REIS, D.J., MINC-GOLOMB, D., and SCHWARTZ, J.P. (1993). Synthesis of nitric oxide in CNS glial cells. TINS 16, 323-328
2. MURPHY, S., and GRZYBICKI, D. (1996). Glial NO: normal and pathological roles. Neuroscientist 2, 90-99.
3. PARK, S.K., and MURPHY, S. (1994). Duration of expression of inducible nitric oxide synthase in glial cells. J. Neurosci. Res. 39, 405-411.
4. GALEA, E., REIS, D.J., and FEINSTEIN, D.L. (1994). Cloning and expression of inducible nitric oxide synthase from rat astrocytes. J. Neurosci. Res. 37, 406-414.
5. GALEA, E., FEINSTEIN, D.L., and REIS, D.J. (1992). Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures. Proc. Natl. Acad. Sci. USA 89, 10945-10949.
6. 2 in rat cultured astrocytes. J. Biol. Chem. 266, 9956-9960.
7. 2 mRNA expression and release in an immortalized astrocyte cell line (DITNC) by LPS. TNF alpha, and IL-1 beta. Interactive effects. Mol. Chem. Neuropathol. 25, 1-17.
8. 2. Crit. Rev. Immunol. 17, 225-283.
9. DIEHL, J.A., TONG, W., SUN, G.Y., and HANNINK, M. (1995). Tumor necrosis factor-α-dependent activation of a RelA homodimer in astrocytes. J. Biol. Chem. 270, 2703-2707.
10. RINK, L., and KIRCHNER, H. (1996). Recent progress in the tumor necrosis factor-alpha field. Int. Arch. Allergy Immunol. 111, 199-209.
11. BANKERS-FULBRIGHT, J.L., KALLI, K.R., and McKEAN, D.J. (1996). Interleukin-1 signal transduction. Life Sci. 59, 61-83.
12. GAO, J., MORRISON, D.C., PARMELY, T.J., RUSSELL, S.W., and MURPHY, W.J. (1997). An interferon - γ-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-γ and lipopolysaccharide. J. Biol. Chem. 272, 1226-1230.
13. KAMIJO, R., HARADA, H., MATSUYAMA, T., BOSLAND, M., GERECITANO, J., SHAPIRO, D., LE, J., KOH, S.I., KIMURA, T., GREEN, S.J., MAK, T.W., TANIGUCHI, T., and VILCEK, J. (1994). Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science 263, 1612-1615.
14. BOEHM, U., KLAMP, T., GROOT, M., and HOWARD, J.C. (1997). Cellular responses to interferon-γ. Annu. Rev. Immunol. 15, 749-795.
15. LEAMAN, D.W., LEUNG, S., LI, X., and STARK, G.R. (1996). Regulation of STAT-dependent pathways by growth factors and cytokines. FASEB J. 10, 1578-1588.
16. NATHAN, C., and XIE, Q. (1994). Regulation of biosynthesis of nitric oxide. J. Biol. Chem. 269, 13725-13728.
17. RADANY, E.H., BRENNER, M., BESNARD, F., BIGORNIA, V., BISHOP, J.M., and DESCHEPPER, C.F. (1992). Directed establishment of rat brain cell lines with the phenotypic characteristics of type I astrocytes. Proc. Natl. Acad. Sci. USA 89, 6467-6471.
18. BRADFORD, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
19. 15N]nitrate in biological fluids. Anal. Biochem. 126, 131-138.
20. SUN, G.Y. (1988). Preparation and analysis of acyl and alkenyl groups of glycerophospholipids from brain subcellular membranes. In: Lipids and Related Compounds. A.A. Boulton, G.B. Baker, and L.A. Horrocks (eds.) Clifton, NJ: Humana Press, pp. 63-82.
21. NISOLI, E., TONELLO, C., BRISCINI, L., and CARRUBA, M.O. (1997). Inducible nitric oxide synthase in rat brown adipocytes: implications for blood flow to brown adipose tissue. Endocrinology 138, 676-682.
22. 2. Biochem. Biophys. Res. Commun. 162, 1030-1036.
23. TOKUNAGA, K., TANIGUCHI, H., YODA, K., SHIMIZU, M., and SAKIYAMA, S. (1986). Nucleotide sequence of a full-length cDNA for mouse cytoskeletal beta-actin mRNA. Nucleic Acids Res. 14, 2829.
24. LYONS, C.R., ORLOFF, G.J., and CUNNINGHAM, J.M. (1992). Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J. Biol. Chem. 267, 6370-6374.
25. MARTIN, E., NATHAN, C., and XIE, Q. (1994). Role of interferon regulatory factor 1 in induction of nitric oxide synthase. J. Exp. Med. 180, 977-984.
26. BROWN, M.C., TOMARAS, G.D., VINCENTI, MR, and TAFFET, S.M. (1997). Two forms of NF-κB1 (p105/p50) in murine macrophages: different regulation by lipopolysaccharide, interleukin-2, and interferon-γ. J. Interferon Cytokine Res. 17, 295-306.
27. PAHAN, K., SHEIKH, F.G., NAMBOODIRI, A.M., and SINGH, I. (1998). N-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes. Free Rad. Biol. Med. 24, 39-48.
28. SCHRECK, R., MEIER, B., MANNEL, D.N., DROGE, W., and BAEUERLE, P.A. (1992). Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J. Exp. Med. 175, 1181-1194.
29. 2 in rat renal mesangial cells. FEBS Lett. 364, 218-222.
30. TOGASHI, H., SASAKI, M., FROHMAN, E., TAIRA, E., RATAN, R.R., DAWSON, T.M., and DAWSON, V.L. (1997). Neuronal (type I) nitric oxide synthase regulates nuclear factor kappa B activity and immunologic (type II) nitric oxide synthase expression. Proc. Natl. Acad. Sci. USA 94, 2676-2680.
31. HATTORI, Y., NAKANISHI, N., and KASAI, K. (1997). Role of nuclear factor kappa B in cytokine-induced nitric oxide and tetrahydrobiopterin synthesis in rat neonatal cardiac myocytes. J. Mol. Cell Cardiol. 29, 1585-1592.
32. HAMILTON, T.A., TANNENBAUM, C.S., and TEBO, J.M. (1996). Cytokine-initiated intracellular signaling pathways. In: Cytokines and The CNS. R.M. Ransohoff and E.N. Benveniste (eds.) Boca Raton, FL: CRS Press, pp. 25-46.
33. 2 in an immortalized astrocyte cell line (DITNC). In: Biological Oxidation & Antioxidants, Molecular Mechanisms & Health Effects. L. Parker and A.H.S. Ong (eds.) Champaign, IL: AOCS Press, pp. 90-103.