Drug targeting to monocytes and macrophages using esterase-sensitive chemical motifs

Journal of Pharmacology and Experimental Therapeutics

Volumn 339, Issue 1, 2011, Pages 132-142

  Needham, Lindsey A ^a   Davidson, Alan H ^a   Bawden, Lindsay J ^a   Belfield, Andrew ^a   Bone, Elisabeth A ^a   Brotherton, Deborah H ^a   Bryant, Sam ^a   Charlton, Michael H ^a   Clark, Vanessa L ^a   Davies, Stephen J ^a   Donald, Alastair ^a   Day, Francesca A ^a   Krige, David ^a   Legris, Valeŕie ^a   McDermott, Joanne ^a   McGovern, Yvonne ^a   Owen, Jo ^a   Patel, Sanjay R ^a   Pintat, Steṕhane ^a   Testar, Richard J ^a   Wells, Graham M A ^a   Moffat, David ^a   Drummond, Alan H ^a   more..

^a Chroma Therapeutics Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLESTERASE; CARBOXYLESTERASE 1; CHR 2875; CHR 2880; CHR 2908; CHR 3111; CHR 3112; CHR 3464; CHR 4487; CHR 5250; CHR 5623; CHR 5805; CHR 6511; CHR 6576; CHR 6907; CHR 6909; CHR 7296; ESTERASE; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; HEAT SHOCK PROTEIN 90 INHIBITOR; HISTONE DEACETYLASE INHIBITOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; SNX 2112; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VORINOSTAT;

ANIMAL EXPERIMENT; ARTHRITIS; ARTICLE; BIOTECHNOLOGY; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG POTENCY; DRUG TARGETING; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACIDS; ANIMALS; ANISOMYCIN; ARTHRITIS; CARBOXYLESTERASE; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOKINES; DRUG DELIVERY SYSTEMS; ENZYME INHIBITORS; ESTERASES; ESTERS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, TRANSGENIC; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80053162877     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.183640     Document Type: Article

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