Dynamic behavior and spontaneous differentiation of mouse embryoid bodies on hydrogel substrates of different surface charge and chemical structures

Tissue Engineering - Part A

Volumn 17, Issue 17-18, 2011, Pages 2343-2357

  Liu, Jian Fang ^a   Chen, Yong Mei ^b,d   Yang, Jing Jing ^b   Kurokawa, Takayuki ^b   Kakugo, Akira ^b   Yamamoto, Kimiko ^c   Gong, Jian Ping ^b  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; AMIDES; CELL CULTURE; GELS; MAMMALS; MORPHOLOGY; POLYSTYRENES; PROPANE; STRUCTURE (COMPOSITION); STYRENE; SURFACE PROPERTIES;

BIOACTIVE FACTOR; CARDIOMYOCYTES; CELL LINEAGE; CULTURE PLATES; DYNAMIC BEHAVIORS; EARLY DIFFERENTIATION; EMBRYOID BODY; HYDROGEL SCAFFOLDS; MORPHOLOGY CHANGES; SODIUM SALT; SPHERICAL MORPHOLOGIES; SULFONIC ACID;

HYDROGELS;

ANIMAL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHEMISTRY; CULTURE TECHNIQUE; CYTOLOGY; EMBRYOID BODY; EMBRYONIC STEM CELL; HYDROGEL; METHODOLOGY; MOUSE; PHYSIOLOGY;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; EMBRYOID BODIES; EMBRYONIC STEM CELLS; HYDROGELS; MICE;

EID: 80053139302     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2011.0034     Document Type: Article

References (57)

1. Hwang, N.S., Varghese, S., and Elisseeff, J. Controlled differentiation of stem cells. Adv Drug Deliv Rev 60, 199, 2008.
2. Hopfl, G., Gassmann, M., and Desbaillets, I. Differentiating embryonic stem cells into embryoid bodies. Methods Mol Biol 254, 79, 2004.
3. Fridley, K.M., Fernandez, I., Li, M.T.A., Kettlewell, R.B., and Roy, K. Unique differentiation profile of mouse embryonic stem cells in rotary and stirred tank bioreactors. Tissue Eng Part A 16, 3285, 2010.
4. Desbaillets, I., Ziegler, U., Groscurth, P., and Gassmann M. Embryoid bodies: an in vitro model of mouse embryogenesis. Exp Physiol 85, 645, 2000.
5. Kehat, I., Kenyagin-Karsenti, D., Snir, M., Segev, H., Amit, M., Gepstein, A., Livne, E., Binah, O., Itskovitz-Eldor, J., and Gepstein, L. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest 108, 407, 2001.
6. Dani, C., Smith, A.G., Dessolin, S., Leroy, P., Staccini, L., Villageois, P., Darimont, C., and Ailhaud, G. Differentiation of embryonic stem cells into adipocytes in vitro. J Cell Sci 110, 1279, 1997.
7. Kramer, J., Hegert, C., Guan, K.M., Wobus, A.M., Muller, P.K., and Rohwedel, J. Embryonic stem cell-derived chondrogenic differentiation in vitro: activation by BMP-2 and BMP-4. Mech Dev 92, 193, 2000.
8. Schuldiner, M., Yanuka, O., Itskovitz-Eldor, J., Melton, D.A., and Benvenisty, N. Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proc Natl Acad Sci USA 97, 11307, 2000.
9. Goldring, M.B., Tsuchimochi, K., and Ijiri, K. The control of chondrogenesis. J Cell Biochem 97, 33, 2006.
10. Burdick, J.A., and Vunjak-Novakovic, G. Engineered microenvironments for controlled stem cell differentiation. Tissue Eng Part A 15, 205, 2009.
11. Vacanti, J.P., and Langer, R. Tissue engineering: the design and fabrication of living replacement devices for surgical reconstruction and transplantation. Lancet 354, S32, 1999.
12. Dawson, E., Mapili, G., Erickson, K., Taqvi, S., and Roy, K. Biomaterials for stem cell differentiation. Adv Drug Deliv Rev 60, 215, 2008.
13. Nguyen, K.T., and West, J.L. Photopolymerizable hydrogels for tissue engineering applications. Biomaterials 23, 4307, 2002.
14. Georges, P.C., and Janmey, P.A. Cell type-specific response to growth on soft materials. J Appl Physiol 98, 1547, 2005.
15. Lee, H.J., Lee, J.S., Chansakul, T., Yu, C., Elisseeff, J.H., and Yu, S.M. Collagen mimetic peptide-conjugated photopolymerizable PEG hydrogel. Biomaterials 27, 5268, 2006.
16. Drury, J.L., and Mooney, D.J. Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials 24, 4337, 2003.
17. Liu, S.Q., Tay, R., Khan, M., Rachel Ee, P.L., Hedrick, J.L., and Yang, Y.Y. Synthetic hydrogels for controlled stem cell differentiation. Soft Matter 6, 67, 2010.
18. Hwang, N.S, Varghese, S., Zhang, Z., and Elisseeff, J. Chondrogenic differentiation of human embryonic stem cellderived cells in arginine-glycine-aspartate modified hydrogels. Tissue Eng 12, 2695, 2006.
19. Weber, L.M., Hayda, K.N., Haskins, K., and Anseth, K.S. The effects of cell-matrix interactions on encapsulated betacell function within hydrogels functionalized with matrixderived adhesive peptides. Biomaterials 28, 3004, 2007.
20. Nicodemus, G.D., and Bryant, S.J. The role of hydrogel structure and dynamic loading on chondrocyte. J Biomech 41, 528, 2008.
21. Engler, A.J., Sen, S., Sweeney, H.L., and Discher, D.E. Matrix elasticity directs stem cell lineage specification. Cell 126, 677, 2006.
22. Fedorovich, N.E., Alblas, J., de Wijn, J.R., Hennink, W.E., Verbout, A.J., and Dhert, W.J. Hydrogels as extracellular matrices for skeletal tissue engineering: state-of-the-art and novel application in organ printing. Tissue Eng 13, 1905, 2007.
23. Young, T.H., Tu, H.R., Chan, C.C., Huang, Y.C., Yen, M.H., Cheng, N.C., Chiu, H.C., and Lin, S.J. The enhancement of dermal papilla cell aggregation by extracellular matrix proteins through effects on cell-substratum adhesivity and cell motility. Biomaterials 30, 5031, 2009.
24. Ryan, P.L., Foty, R.A., Kohn, J., and Steinberg, M.S. Tissue spreading on implantable substrates is a competitive outcome of cell-cell vs. cell-substratum adhesivity. Proc Natl Acad Sci USA 98, 4323, 2001.
25. Young, T.H., Lee, C.Y., Chiu, H.C., Hsu, C.J., and Lin, S.J. Self-assembly of dermal papilla cells into inductive spheroidal microtissues on poly (ethylene-co-vinyl alcohol) membranes for hair follicle regeneration. Biomaterials 29, 3521, 2008.
26. Lin, S.J., Jee, S.H., Hsaio, W.C., Lee, S.J., and Young, T.H. Formation of melanocyte spheroids on the chitosan-coated surface. Biomaterials 26, 1413, 2005.
27. Kundu, A.K., Khatiwala, C.B., and Putnam, A.J. Extracellular matrix remodeling, integrin expression, and downstream signaling pathways influence the osteogenic differentiation of mesenchymal stem cells on poly(lactide- coglycolide) substrates. Tissue Eng Part A 15, 273, 2009.
28. Moreau, J.E., Bramono, D.S., Horan, R.L., Kaplan, D.L., and Altman, G.H. Sequential biochemical and mechanical stimulation in the development of tissue-engineered ligaments. Tissue Eng Part A 14, 1161, 2008.
29. Ryan, P.L., Foty, R.A., Kohn, J., and Steinberg, M.S. Tissue spreading on implantable substrates is a competitive outcome of cell-cell vs. cell-substratum adhesivity. Proc Natl Acad Sci USA 98, 4323, 2001.
30. Chen, Y.M., Shiraishi, N., Satokawa, H., Kakugo, A., Narita, T., Gong, J.P., Osada, Y., Yamamoto, K., and Ando, J. Cultivation of endothelial cells on adhesive protein-free synthetic polymer gels. Biomaterials 26, 4588, 2005.
31. Chen, Y.M., Ogawa, R., Kakugo, A., Osada, Y., and Gong, J.P. Dynamic cell behavior on synthetic hydrogels with different charge densities. Soft Matter 5, 1804, 2009.
32. Chen, Y.M., Gong, J.P., Tanaka, M., Yasuda, K., Yamamoto, S., Shimomura, M., and Osada, Y. Tuning of cell proliferation on tough gels by critical charge effect. J Biomed Mater Res A 88, 74, 2009.
33. Chen, Y.M., Yang, J.J., and Gong, J.P. Adhesion, spreading, and proliferation of endothelial cells on charged hydrogels. J Adhes 85, 839, 2009.
34. Yang, J.J., Chen, Y.M., Liu, J.F., Kurokawa, T., and Gong, J.P. Spontaneous redifferentiation of dedifferentiated human articular chondrocytes on hydrogel surfaces. Tissue Eng Part A 16, 2529, 2010.
35. Kwon, H.J., Yasuda, K., Ohmiya, Y., Honma, K., Chen, Y.M., and Gong, J.P. In vitro differentiation of chondrogenic ATDC5 cells is enhanced by culturing on synthetic hydrogels with various charge densities. Acta Biomater 6, 494, 2010.
36. Gong, J.P., Katsuyama, Y., Kurokawa, T., and Osada, Y. Double-network hydrogels with extremely high mechanical strength. Adv Mater 15, 1155, 2003.
37. Chastain, S.R., Kundu, A.K., Dhar, S., Calvert, J.W., and Putnam, A.J. Adhesion of mesenchymal stem cells to polymer scaffolds occurs via distinct ECM ligands and controls their osteogenic differentiation. J Biomed Mater Res A 78, 73, 2006.
38. Yamashita, J., Itoh, H., Hirashima, M., Ogawa, M., Nishikawa, S., Yurugi, T., Naito, M., Nakao, K., and Nishikawa, S.I. Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature 408, 92, 2000.
39. Yamamoto, K., Sokabe, T., Watabe, T., Miyazono, K., Yamashita, J.K., Obi, S., Ohura, N., Matsushita, A., Kamiya, A., and Ando, J. Fluid shear stress induces differentiation of Flk-1-positive embryonic stem cells into vascular endothelial cells in vitro. Am J Physiol Heart Circ Physiol 288, H1915, 2005.
40. Gassmann, M., Donoho, G., and Berg, P. Maintenance of an extrachromosomal plasmid vector in mouse embryonic stem cells. Proc Natl Acad Sci 92, 1292, 1995.
41. Kurosawa, H. Methods for inducing embryoid body formation: in vitro differentiation system of embryonic stem cells, J Biosci Bioeng 103, 389, 2007.
42. Dang, S.M., Kyba, M., Perlingeiro, R., Daley, G.Q., and Zandstra, P.W. Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems. Biotechnol Bioeng 78, 442, 2002.
43. Ma, W., Fitzgerald, W., Liu, Q.Y., O'Shaughnessy, T.J., Maric, D., Lin, H.J., Alkon, D.L., and Barker, J.L. CNS stem and progenitor cell differentiation into functional neuronal circuits in three-dimensional collagen gels. Exp Neurol 190, 276, 2004.
44. Baharvand, H., Azarnia, M., Parivar, K., and Ashtiani, S.K. The effect of extracellular matrix on embryonic stem cellderived cardiomyocytes. J Mol Cell Cardiol 38, 495, 2005.
45. Muller, M., Fleischmann, B.K., Selbert, S., Ji, G.J., Endl, E., Middeler, G., Muller, O.J., Schlenke, P., Frese, S., Wobus, A.M., Hescheler, J., Katus, H.A., and Franz, W.M. Selection of ventricular-like cardiomyocytes from ES cells in vitro. FASEB J 14, 2540, 2000.
46. O'Connor, M.D., Kardel, M.D., Iosfina, I., Youssef, D., Lu, M., Li, M.M., Vercauteren, S., Nagy, A., and Eaves, C.J. Alkaline phosphatase-positive colony formation is a sensitive, specific, and quantitative indicator of undifferentiated human embryonic stem cells. Stem cells 26, 1109, 2008.
47. Palmqvist, L., Glover, C.H., Hsu, L., Lu, M., Bossen, B., Piret, J.M., Humphries, R.K., and Helgason, C.D. Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency. Stem Cells 23, 663, 2005.
48. Latour, R.A. Biomaterials: protein-surface interactions. In: Wnek, G.E., and Bowlin, G.L., eds. The Encyclopedia of Biomaterials and Biomedical Engineering. London: Informa Healthcare, 2005, pp. 1-15.
49. Sivaraman, B., Fears, K.P., and Latour, R.A. Investigation of the effects of surface chemistry and solution concentration on the conformation of adsorbed proteins using an improved circular dichroism method. Langmuir 25, 3050, 2009.
50. Calonder, C., Matthew, H.W.T., and Van Tassel, P.R. Adsorbed layers of oriented fibronectin: A strategy to control cell-surface interactions. J Biomed Mater Res A 75A, 316, 2005.
51. Cohavi, O., Corni, S., De Rienzo, F., Di Felice, R., Gottschalk, K.E., Hoefling, M., Kokh, D., Molinari, E., Schreiber, G., Vaskevich, A., and Wade, R.C. Protein-surface interactions: challenging experiments and computations. J Mol Recognit 23, 259, 2010.
52. Wertz, C.F., and Santore, M.M. Effect of surface hydrophobicity on adsorption and relaxation kinetics of albumin and fibrinogen: single-species and competitive behavior. Langmuir 17, 3006, 2001.
53. Steele, J.G., Dalton, B.A., Johnson, G., and Underwood, P.A. Adsorption of fibronectin and vitronectin onto Primaria and tissue culture polystyrene and relationship to the mechanism of initial attachment of human vein endothelial cells and BHK-21 fibroblasts. Biomaterials 16, 1057, 1995.
54. Wilson, C.J., Clegg, R.E., Leavesley, D.I., and Pearcy, M.J. Mediation of biomaterial-cell interactions by adsorbed proteins: a review. Tissue Eng 11, 1, 2005.
55. Maltsev, V.A., Wobus, A.M., Rohwedel, J., Bader, M., and Hescheler, J. Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiacspecific genes and ionic currents. Circ Res 75, 233, 1994.
56. Kubo, A., Shinozaki, K., Shannon, J.M., Kouskoff, V., Kennedy, M., Woo, S., Fehling, H.J., and Keller, G. Development of definitive endoderm from embryonic stem cells in culture. Development 131, 1651, 2004.
57. Sachinidis, A., Fleischmann, B.K., Kolossov, E., Wartenberg, M., Sauer, H., and Hescheler, J. Cardiac specific differentiation of mouse embryonic stem cells. Cardiovasc Res 58, 278, 2003.