CD8 + lymphocyte depletion without SIV infection does not produce metabolic changes or pathological abnormalities in the rhesus macaque brain

Journal of Medical Primatology

Volumn 40, Issue 5, 2011, Pages 300-309

  Ratai, E M ^a,b   Pilkenton, S ^a,b,f   He, J ^a,b   Fell, R ^a   Bombardier, J P ^a   Joo, C G ^a,b   Lentz, M R ^a,b   Kim, W K ^b,c,g   Burdo, T H ^c,d   Autissier, P ^c,d   Annamalai, L ^b,h   Curran, E ^b   O'Neil, S P ^b,i   Westmoreland, S V ^b   Williams, K C ^c,d   Masliah, E ^e   Gilberto Gonzalez R ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d BOSTON COLLEGE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f FRAMINGHAM STATE UNIVERSITY   (United States)

^g EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^h OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

ⁱ PFIZER INC   (United States)

Author keywords

Accelerated SIV macaque model; Magnetic resonance spectroscopy; NeuroAIDS

Indexed keywords

CD8 ANTIGEN;

ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN DAMAGE; CD8+ T LYMPHOCYTE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE DEPLETION; METABOLIC REGULATION; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS INFECTION;

ANIMALS; ANTIBODIES, MONOCLONAL; ASTROCYTES; BRAIN; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; ENCEPHALITIS, VIRAL; FLOW CYTOMETRY; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE DEPLETION; MACACA MULATTA; MAGNETIC RESONANCE SPECTROSCOPY; MICROFILAMENT PROTEINS; MICROGLIA; MICROTUBULE-ASSOCIATED PROTEINS; MONKEY DISEASES; NEURONS; PROTONS; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; SYNAPTOPHYSIN;

ANIMALIA; MACACA MULATTA; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 80053122157     PISSN: 00472565     EISSN: 16000684     Source Type: Journal    
DOI: 10.1111/j.1600-0684.2011.00475.x     Document Type: Article

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