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Volumn 19, Issue 10, 2011, Pages 1090-1094

Finding disease genes: A fast and flexible approach for analyzing high-throughput data

Author keywords

disease genes; linkage disequilibrium; sequencing

Indexed keywords

ARTICLE; COMPUTER PROGRAM; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC LINKAGE; GENOTYPE; HIGH THROUGHPUT SCREENING; PRIORITY JOURNAL; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 80053053102     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2011.81     Document Type: Article
Times cited : (6)

References (25)
  • 1
    • 65949107547 scopus 로고    scopus 로고
    • Common genetic variation and human traits
    • Goldstein DB: Common genetic variation and human traits. N Engl J Med 2009; 360: 1696-1698.
    • (2009) N Engl J Med , vol.360 , pp. 1696-1698
    • Goldstein, D.B.1
  • 3
    • 0023272069 scopus 로고
    • Mapping of DNA markers linked to the cystic fibrosis locus on the long arm of chromosome 7
    • Zengerling S, Tsui LC, Grzeschik KH, Olek K, Riordan JR, Buchwald M: Mapping of DNA markers linked to the cystic fibrosis locus on the long arm of chromosome 7. Am J Hum Genet 1987; 40: 228-236. (Pubitemid 17079443)
    • (1987) American Journal of Human Genetics , vol.40 , Issue.3 , pp. 228-236
    • Zengerling, S.1    Olek, K.2    Tsui, L.-C.3
  • 4
    • 0027031612 scopus 로고
    • Mapping of a gene predisposing to early-onset Alzheimers disease to chromosome 14q24.3
    • Van Broeckhoven C, Backhovens H, Cruts M, et al. Mapping of a gene predisposing to early-onset Alzheimers disease to chromosome 14q24.3. Nat Genet 1992; 2: 335-339.
    • (1992) Nat Genet , vol.2 , pp. 335-339
    • Van Broeckhoven, C.1    Backhovens, H.2    Cruts, M.3
  • 5
    • 0029059069 scopus 로고
    • Localization of a gene for partial epilepsy to chromosome 10q
    • Ottman R, Risch N, Hauser WA, et al. Localization of a gene for partial epilepsy to chromosome 10q. Nat Genet 1995; 10: 56-60.
    • (1995) Nat Genet , vol.10 , pp. 56-60
    • Ottman, R.1    Risch, N.2    Hauser, W.A.3
  • 8
    • 57349131186 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder
    • Zhou K, Dempfle A, Arcos-Burgos M, et al. Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder. Am J Med Genet B (Neuropsychiatr Genet) 2008; 147B: 1392-1398.
    • (2008) Am J Med Genet B (Neuropsychiatr Genet) , vol.147 , pp. 1392-1398
    • Zhou, K.1    Dempfle, A.2    Arcos-Burgos, M.3
  • 9
    • 8844250042 scopus 로고    scopus 로고
    • Ignoring linkage disequilibrium among tightly linked markers induces false-positive evidence of linkage for affected sib pair analysis
    • DOI 10.1086/426000
    • Huang Q, Shete S, Amos CI: Ignoring linkage disequilibrium among tightly linked markers induces false-positive evidence of linkage for affected sib pair analysis. Am J Hum Genet 2004; 75: 1106-1112. (Pubitemid 39532077)
    • (2004) American Journal of Human Genetics , vol.75 , Issue.6 , pp. 1106-1112
    • Huang, Q.1    Shete, S.2    Amos, C.I.3
  • 11
    • 30344443251 scopus 로고    scopus 로고
    • Bias of allele-sharing linkage statistics in the presence of intermarker linkage disequilibrium
    • Goode EL, Badzioch MD, Jarvik GP: Bias of allele-sharing linkage statistics in the presence of intermarker linkage disequilibrium. BMC Genet 2005; 6: S82.
    • (2005) BMC Genet , vol.6
    • Goode, E.L.1    Badzioch, M.D.2    Jarvik, G.P.3
  • 12
    • 38149016948 scopus 로고    scopus 로고
    • Examining the effect of linkage disequilibrium between markers on the type i error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data
    • Kim Y, Duggal P, Gillanders EM, Kim H, Bailey-Wilson JE: Examining the effect of linkage disequilibrium between markers on the type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data. Genet Epidemiol 2008; 32: 41-51.
    • (2008) Genet Epidemiol , vol.32 , pp. 41-51
    • Kim, Y.1    Duggal, P.2    Gillanders, E.M.3    Kim, H.4    Bailey-Wilson, J.E.5
  • 13
    • 72149122117 scopus 로고    scopus 로고
    • Multiple subsampling of dense SNP data localizes disease genes with increased precision
    • Stewart WCL, Peljto AL, Greenberg DA: Multiple subsampling of dense SNP data localizes disease genes with increased precision. Hum Hered 2010; 69: 152-159.
    • (2010) Hum Hered , vol.69 , pp. 152-159
    • Wcl, S.1    Peljto, A.L.2    Greenberg, D.A.3
  • 14
    • 27744559569 scopus 로고    scopus 로고
    • Multipoint linkage analysis for a very dense set of markers
    • DOI 10.1002/gepi.20089
    • Bacanu S: Multipoint linkage analysis for a very dense set of markers. Bioinformatics 2005; 29: 195-203. (Pubitemid 41598061)
    • (2005) Genetic Epidemiology , vol.29 , Issue.3 , pp. 195-203
    • Bacanu, S.-A.1
  • 15
    • 21444450506 scopus 로고    scopus 로고
    • SNPLINK: Multipoint linkage analysis of densely distributed SNP data incorporating automated linkage disequilibrium removal
    • DOI 10.1093/bioinformatics/bti449
    • Webb EL, Sellick GS, Houlston RS: SNPLINK: multipoint linkage analysis of densely distributed SNP data incorporating automated linkage disequilibrium removal. Bioinformatics 2005; 21: 3060-3061. (Pubitemid 40916436)
    • (2005) Bioinformatics , vol.21 , Issue.13 , pp. 3060-3061
    • Webb, E.L.1    Sellick, G.S.2    Houlston, R.S.3
  • 16
    • 64149094545 scopus 로고    scopus 로고
    • Linkage analysis with dense SNP maps in isolated populations
    • Bellenguez C, Ober C, Bourgain C: Linkage analysis with dense SNP maps in isolated populations. Hum Hered 2009; 68: 87-97.
    • (2009) Hum Hered , vol.68 , pp. 87-97
    • Bellenguez, C.1    Ober, C.2    Bourgain, C.3
  • 17
    • 27244437783 scopus 로고    scopus 로고
    • Handling marker-marker linkage disequilibrium: Pedigree analysis with clustered markers
    • DOI 10.1086/497345
    • Abecasis GR, Wigginton JE: Handling marker-marker linkage disequilibrium: pedigree analysis with clustered markers. Am J Hum Genet 2005; 77: 754-767. (Pubitemid 41513278)
    • (2005) American Journal of Human Genetics , vol.77 , Issue.5 , pp. 754-767
    • Abecasis, G.R.1    Wigginton, J.E.2
  • 18
    • 38049093738 scopus 로고    scopus 로고
    • Analysis of high-density single-nucleotide polymorphism data: Three novel methods that control for linkage disequilibrium between markers in a linkage analysis
    • Allen-Brady K, Horne BD, Malhotra A, Teerlink C, Camp NJ, Thomas A: Analysis of high-density single-nucleotide polymorphism data: three novel methods that control for linkage disequilibrium between markers in a linkage analysis. BMC Proc 2007; 1: S160.
    • (2007) BMC Proc , vol.1
    • Allen-Brady, K.1    Horne, B.D.2    Malhotra, A.3    Teerlink, C.4    Camp, N.J.5    Thomas, A.6
  • 19
    • 38049004829 scopus 로고    scopus 로고
    • Modeling linkage disequilibrium in exact linkage computations: A comparison of first-order markov approaches and the clustered-markers approach
    • Albers C, Kappen HJ: Modeling linkage disequilibrium in exact linkage computations: a comparison of first-order markov approaches and the clustered-markers approach. BMC Proc 2007; 1: S159.
    • (2007) BMC Proc , vol.1
    • Albers, C.1    Kappen, H.J.2
  • 20
    • 58849166616 scopus 로고    scopus 로고
    • A general method for linkage disequilibrium correction for multipoint linkage and association
    • Kurbasic A, Hossjer O: A general method for linkage disequilibrium correction for multipoint linkage and association. Genet Epidemiol 2008; 32: 647-657.
    • (2008) Genet Epidemiol , vol.32 , pp. 647-657
    • Kurbasic, A.1    Hossjer, O.2
  • 21
    • 0030728925 scopus 로고    scopus 로고
    • Allele-sharing models: LOD scores and accurate linkage tests
    • DOI 10.1086/301592
    • Kong A, Cox NJ: Allele-sharing models: LOD scores and accurate linkage tests. Am J Hum Genet 1997; 61: 1179-1188. (Pubitemid 27492328)
    • (1997) American Journal of Human Genetics , vol.61 , Issue.5 , pp. 1179-1188
    • Kong, A.1    Cox, N.J.2
  • 22
  • 23
    • 74849100584 scopus 로고    scopus 로고
    • Novel loci interacting epistatically with bone morphogenetic protein receptor 2 cause familial pulmonary arterial hypertension
    • Rodriguez-Murillo L, Subaran R, Stewart WCL, et al. Novel loci interacting epistatically with bone morphogenetic protein receptor 2 cause familial pulmonary arterial hypertension. J Heart Lung Transplant 2009; 29: 174-180.
    • (2009) J Heart Lung Transplant , vol.29 , pp. 174-180
    • Rodriguez-Murillo, L.1    Subaran, R.2    Wcl, S.3
  • 24
    • 77952574849 scopus 로고    scopus 로고
    • Uncovering the roles of rare variants in common disease through whole-genome sequencing
    • Cirulli ET, Goldstein DB: Uncovering the roles of rare variants in common disease through whole-genome sequencing. Nat Rev Genet 2010; 11: 415-425.
    • (2010) Nat Rev Genet , vol.11 , pp. 415-425
    • Cirulli, E.T.1    Goldstein, D.B.2
  • 25
    • 78049416608 scopus 로고    scopus 로고
    • The characterization of twenty sequenced human genomes
    • Pelak K, Shianna KV, Ge D, et al. The characterization of twenty sequenced human genomes. PloS Genet 2010; 6: e1001111.
    • (2010) PloS Genet , vol.6
    • Pelak, K.1    Shianna, K.V.2    Ge, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.