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Volumn 3, Issue 4, 2011, Pages 151-158

Clinical Applications of Polymeric Micelle Carrier Systems in Chemotherapy and Image Diagnosis of Solid Tumors

Author keywords

Chemotherapy; Drug carriers; Image diagnosis; Polymeric micelles; Solid tumors

Indexed keywords

ALBUMIN; ANTINEOPLASTIC AGENT; CONTRAST MEDIUM; COPOLYMER; DOXORUBICIN; DRUG CARRIER; GENEXOL PM; NK 105; NK 911; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; PACLITAXEL; SP 1049C; UNCLASSIFIED DRUG;

EID: 80053051929     PISSN: 18783317     EISSN: 18783325     Source Type: Journal    
DOI: 10.1016/j.jecm.2011.06.002     Document Type: Review
Times cited : (111)

References (79)
  • 2
    • 0038759662 scopus 로고    scopus 로고
    • Amphiphilic block copolymers for drug delivery
    • Adams M.L., Lavasanifar A., Kwon G.S. Amphiphilic block copolymers for drug delivery. J Pharm Sci 2003, 92:1343-1355.
    • (2003) J Pharm Sci , vol.92 , pp. 1343-1355
    • Adams, M.L.1    Lavasanifar, A.2    Kwon, G.S.3
  • 4
  • 5
    • 40549138658 scopus 로고    scopus 로고
    • Polymeric micelles as nano-sized drug carrier systems
    • American Scientific Publishers, Stevenson Ranch, Y. Tabata (Ed.)
    • Yokoyama M. Polymeric micelles as nano-sized drug carrier systems. Nanoparticles for pharmaceutical applications 2007, 63-72. American Scientific Publishers, Stevenson Ranch. Y. Tabata (Ed.).
    • (2007) Nanoparticles for pharmaceutical applications , pp. 63-72
    • Yokoyama, M.1
  • 6
    • 76149146724 scopus 로고    scopus 로고
    • Polymeric micelles as a novel drug carrier system and their required considerations for clinical trials
    • Yokoyama M. Polymeric micelles as a novel drug carrier system and their required considerations for clinical trials. Expert Opin Drug Deliv 2010, 7:145-158.
    • (2010) Expert Opin Drug Deliv , vol.7 , pp. 145-158
    • Yokoyama, M.1
  • 7
    • 78649810957 scopus 로고    scopus 로고
    • Advances in polymeric micelles for drug delivery and tumor targeting
    • Kedar U., Phutane P., Shidhaye S., Kadam V. Advances in polymeric micelles for drug delivery and tumor targeting. Nanomedicine 2010, 6:714-729.
    • (2010) Nanomedicine , vol.6 , pp. 714-729
    • Kedar, U.1    Phutane, P.2    Shidhaye, S.3    Kadam, V.4
  • 8
    • 78651279520 scopus 로고    scopus 로고
    • Polymeric micelles in anticancer therapy: targeting, imaging and triggered release
    • Oerlemans C., Bult W., Bos M., Storm G., Nijsen J.F., Hennink W.E. Polymeric micelles in anticancer therapy: targeting, imaging and triggered release. Pharm Res 2010, 27:2569-2589.
    • (2010) Pharm Res , vol.27 , pp. 2569-2589
    • Oerlemans, C.1    Bult, W.2    Bos, M.3    Storm, G.4    Nijsen, J.F.5    Hennink, W.E.6
  • 9
    • 49549135578 scopus 로고
    • Block and graft copolymer micelles in solution
    • Tuzar Z., Kratochvil P. Block and graft copolymer micelles in solution. Adv Colloid Interface Sci 1976, 6:201-232.
    • (1976) Adv Colloid Interface Sci , vol.6 , pp. 201-232
    • Tuzar, Z.1    Kratochvil, P.2
  • 10
    • 0028374379 scopus 로고
    • Investigation of polystyrene-poly(ethylene oxide) block copolymer micelle formation in organic and aqueous solutions by nonradiative energy transfer experiments
    • Calderara F., Hruska Z., Hurtrez G., Lerch J.P., Nugay T., Riess G. Investigation of polystyrene-poly(ethylene oxide) block copolymer micelle formation in organic and aqueous solutions by nonradiative energy transfer experiments. Macromolecules 1994, 27:1210-1215.
    • (1994) Macromolecules , vol.27 , pp. 1210-1215
    • Calderara, F.1    Hruska, Z.2    Hurtrez, G.3    Lerch, J.P.4    Nugay, T.5    Riess, G.6
  • 11
    • 0029247199 scopus 로고
    • Exchange of chains between micelles of labeled polystyrene-block-poly(oxyethylene) as monitored by nonradiative singlet energy transfer
    • Wang Y., Kausch C.M., Chun M., Quirk R.P., Mattice W.L. Exchange of chains between micelles of labeled polystyrene-block-poly(oxyethylene) as monitored by nonradiative singlet energy transfer. Macromolecules 1995, 28:904-911.
    • (1995) Macromolecules , vol.28 , pp. 904-911
    • Wang, Y.1    Kausch, C.M.2    Chun, M.3    Quirk, R.P.4    Mattice, W.L.5
  • 12
    • 0026415708 scopus 로고
    • Poly(styrene-ethylene oxide) block copolymer micelle formation in water: a fluorescence probe study
    • Wilhelm M., Zhao C.L., Wang Y., Xu R., Winnik R.A. Poly(styrene-ethylene oxide) block copolymer micelle formation in water: a fluorescence probe study. Macromolecules 1991, 24:1033-1040.
    • (1991) Macromolecules , vol.24 , pp. 1033-1040
    • Wilhelm, M.1    Zhao, C.L.2    Wang, Y.3    Xu, R.4    Winnik, R.A.5
  • 13
    • 0026241176 scopus 로고
    • Colloidal properties of block ionomers. I. Characterization of reverse micelles of styrene-b-metal methacrylate diblocks by size-exclusion chromatography
    • Desjardins A., Eisenberg A. Colloidal properties of block ionomers. I. Characterization of reverse micelles of styrene-b-metal methacrylate diblocks by size-exclusion chromatography. Macromolecules 1991, 24:5779-5790.
    • (1991) Macromolecules , vol.24 , pp. 5779-5790
    • Desjardins, A.1    Eisenberg, A.2
  • 14
    • 0026887072 scopus 로고
    • Preparation of micelle-forming polymer-drug conjugates
    • Yokoyama M., Kwon G.S., Kataoka K. Preparation of micelle-forming polymer-drug conjugates. Bioconjugate Chem 1992, 3:295-301.
    • (1992) Bioconjugate Chem , vol.3 , pp. 295-301
    • Yokoyama, M.1    Kwon, G.S.2    Kataoka, K.3
  • 15
    • 0022405518 scopus 로고
    • Optimization of macromolecular prodrugs of the antitumor antibiotic adriamycin
    • Hoes C.J.T., Potman W., Feijen J. Optimization of macromolecular prodrugs of the antitumor antibiotic adriamycin. J Control Release 1985, 2:205-213.
    • (1985) J Control Release , vol.2 , pp. 205-213
    • Hoes, C.J.T.1    Potman, W.2    Feijen, J.3
  • 16
    • 0023141221 scopus 로고
    • Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers I. Evaluation of daunomycin and puromycin conjugates in vitro
    • Duncan R., Kopeckova-Rejmanova P., Kopecek J. Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers I. Evaluation of daunomycin and puromycin conjugates in vitro. Br J Cancer 1987, 55:165-174.
    • (1987) Br J Cancer , vol.55 , pp. 165-174
    • Duncan, R.1    Kopeckova-Rejmanova, P.2    Kopecek, J.3
  • 17
    • 0023618409 scopus 로고
    • A novel covalent modification of antibodies at their amino groups with retention of antigen-binding activity
    • Endo N., Umemoto N., Hara T. A novel covalent modification of antibodies at their amino groups with retention of antigen-binding activity. J Immunol Methods 1987, 104:253-258.
    • (1987) J Immunol Methods , vol.104 , pp. 253-258
    • Endo, N.1    Umemoto, N.2    Hara, T.3
  • 18
    • 0024438996 scopus 로고
    • Poly(carboxylic acid) polymers as carriers for anthracyclines
    • Zunino F., Pratesi G., Micheloni A. Poly(carboxylic acid) polymers as carriers for anthracyclines. J Control Release 1989, 10:65-73.
    • (1989) J Control Release , vol.10 , pp. 65-73
    • Zunino, F.1    Pratesi, G.2    Micheloni, A.3
  • 19
    • 0031646316 scopus 로고    scopus 로고
    • Novel polyion complex micelles entrapping enzyme molecules in the core: Preparation of narrowly-distributed micelles from lysozyme and poly(ethylene glycol)-poly(aspartic acid) block copolymer in aqueous medium
    • Harada A., Kataoka K. Novel polyion complex micelles entrapping enzyme molecules in the core: Preparation of narrowly-distributed micelles from lysozyme and poly(ethylene glycol)-poly(aspartic acid) block copolymer in aqueous medium. Macromolecules 1998, 31:288-294.
    • (1998) Macromolecules , vol.31 , pp. 288-294
    • Harada, A.1    Kataoka, K.2
  • 20
    • 0030385934 scopus 로고    scopus 로고
    • Spontaneous formation of polyion complex micelles with narrow distribution from antisense oligonucleotide and cationic block copolymer in physiological saline
    • Kataoka K., Togawa H., Harada A., Yasugi K., Matsumoto T., Katayose S. Spontaneous formation of polyion complex micelles with narrow distribution from antisense oligonucleotide and cationic block copolymer in physiological saline. Macromolecules 1996, 29:8556-8557.
    • (1996) Macromolecules , vol.29 , pp. 8556-8557
    • Kataoka, K.1    Togawa, H.2    Harada, A.3    Yasugi, K.4    Matsumoto, T.5    Katayose, S.6
  • 22
    • 0032803387 scopus 로고    scopus 로고
    • Preparation and characterization of self-assembled polymer-metal complex micelle from cis-dichlorodiammineplatinum (II) and poly(ethylene glycol)-poly(α,β-aspartic acid) block copolymer in an aqueous medium
    • Nishiyama N., Yokoyama M., Aoyagi T., Okano T., Sakurai Y., Kataoka K. Preparation and characterization of self-assembled polymer-metal complex micelle from cis-dichlorodiammineplatinum (II) and poly(ethylene glycol)-poly(α,β-aspartic acid) block copolymer in an aqueous medium. Langmuir 1999, 15:377-383.
    • (1999) Langmuir , vol.15 , pp. 377-383
    • Nishiyama, N.1    Yokoyama, M.2    Aoyagi, T.3    Okano, T.4    Sakurai, Y.5    Kataoka, K.6
  • 25
    • 67349103085 scopus 로고    scopus 로고
    • Preparation and in vivo imaging of PEG-poly(L-lysine)-based polymeric micelle MRI contrast agents
    • Shiraishi K., Kawano K., Minowa T., Maitani Y., Yokoyama M. Preparation and in vivo imaging of PEG-poly(L-lysine)-based polymeric micelle MRI contrast agents. J Control Release 2009, 136:14-20.
    • (2009) J Control Release , vol.136 , pp. 14-20
    • Shiraishi, K.1    Kawano, K.2    Minowa, T.3    Maitani, Y.4    Yokoyama, M.5
  • 26
    • 78649324786 scopus 로고    scopus 로고
    • Synthesis of poly(ethylene glycol)-b-poly(L-lysine) block copolymers having Gd-DOTA as MRI contrast agent and their polymeric micelle formation by polyion complexation
    • Shiraishi K., Kawano K., Maitani Y., Yokoyama M. Synthesis of poly(ethylene glycol)-b-poly(L-lysine) block copolymers having Gd-DOTA as MRI contrast agent and their polymeric micelle formation by polyion complexation. J Control Release 2010, 148:160-167.
    • (2010) J Control Release , vol.148 , pp. 160-167
    • Shiraishi, K.1    Kawano, K.2    Maitani, Y.3    Yokoyama, M.4
  • 27
    • 0030234981 scopus 로고    scopus 로고
    • Targetable drug carriers: Present status and a future perspective
    • Yokoyama M., Okano T. Targetable drug carriers: Present status and a future perspective. Adv Drug Deliv Rev 1996, 21:77-80.
    • (1996) Adv Drug Deliv Rev , vol.21 , pp. 77-80
    • Yokoyama, M.1    Okano, T.2
  • 28
    • 0030175405 scopus 로고    scopus 로고
    • Importance of pharmacokinetic considerations in the development of drug delivery systems
    • Sugiyama Y. Importance of pharmacokinetic considerations in the development of drug delivery systems. Adv Drug Deliv Rev 1996, 19:333-334.
    • (1996) Adv Drug Deliv Rev , vol.19 , pp. 333-334
    • Sugiyama, Y.1
  • 29
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 1986, 46:6387-6392.
    • (1986) Cancer Res , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 30
    • 0026926609 scopus 로고
    • Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo
    • Maeda H., Seymour L.W., Miyamoto Y. Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo. Bioconjug Chem 1992, 3:351-361.
    • (1992) Bioconjug Chem , vol.3 , pp. 351-361
    • Maeda, H.1    Seymour, L.W.2    Miyamoto, Y.3
  • 31
    • 79953054576 scopus 로고    scopus 로고
    • The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
    • Fang J., Nakamura H., Maeda H. The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliv Rev 2011, 63:136-151.
    • (2011) Adv Drug Deliv Rev , vol.63 , pp. 136-151
    • Fang, J.1    Nakamura, H.2    Maeda, H.3
  • 32
    • 0028055226 scopus 로고
    • Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes
    • Litzinger D.C., Buiting A.M.J., van Rooijen N., Huang L. Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes. Biochim Biophys Acta 1994, 1190:99-107.
    • (1994) Biochim Biophys Acta , vol.1190 , pp. 99-107
    • Litzinger, D.C.1    Buiting, A.M.J.2    van Rooijen, N.3    Huang, L.4
  • 33
    • 0029895325 scopus 로고    scopus 로고
    • Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic consideration on biodistribution
    • Takakura Y., Hashida M. Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic consideration on biodistribution. Pharm Res 1996, 13:820-831.
    • (1996) Pharm Res , vol.13 , pp. 820-831
    • Takakura, Y.1    Hashida, M.2
  • 34
    • 0023665448 scopus 로고
    • The organ distribution and circulation time of intravenously injected colloidal carriers sterically stabilized with a block copolymer - Poloxamine 908
    • Illum L., Davis S.S., Miller R.H., Mak E., West P. The organ distribution and circulation time of intravenously injected colloidal carriers sterically stabilized with a block copolymer - Poloxamine 908. Life Sci 1987, 40:367-374.
    • (1987) Life Sci , vol.40 , pp. 367-374
    • Illum, L.1    Davis, S.S.2    Miller, R.H.3    Mak, E.4    West, P.5
  • 35
    • 0000428523 scopus 로고
    • Preparation of adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. A new type of polymeric anticancer agent
    • Yokoyama M., Inoue S., Kataoka K., Yui N., Sakurai Y. Preparation of adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. A new type of polymeric anticancer agent. Makromolekulare Chemie Rapid Communications 1987, 8:431-435.
    • (1987) Makromolekulare Chemie Rapid Communications , vol.8 , pp. 431-435
    • Yokoyama, M.1    Inoue, S.2    Kataoka, K.3    Yui, N.4    Sakurai, Y.5
  • 36
    • 0025343062 scopus 로고
    • Characterization and anti-cancer activity of micelle-forming polymeric anti-cancer drug, adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
    • Yokoyama M., Miyauchi M., Yamada N., Okano T., Sakurai Y., Kataoka K., Inoue S. Characterization and anti-cancer activity of micelle-forming polymeric anti-cancer drug, adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. Cancer Res 1990, 50:1693-1700.
    • (1990) Cancer Res , vol.50 , pp. 1693-1700
    • Yokoyama, M.1    Miyauchi, M.2    Yamada, N.3    Okano, T.4    Sakurai, Y.5    Kataoka, K.6    Inoue, S.7
  • 37
    • 0025874282 scopus 로고
    • Toxicity and antitumor activity against solid tumors of micelle-forming polymeric drug and its extremely long circulation in blood
    • Yokoyama M., Okano T., Sakurai Y., Ekimoto H., Shibazaki C., Kataoka K. Toxicity and antitumor activity against solid tumors of micelle-forming polymeric drug and its extremely long circulation in blood. Cancer Res 1991, 51:3229-3236.
    • (1991) Cancer Res , vol.51 , pp. 3229-3236
    • Yokoyama, M.1    Okano, T.2    Sakurai, Y.3    Ekimoto, H.4    Shibazaki, C.5    Kataoka, K.6
  • 38
    • 0028346185 scopus 로고
    • Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates
    • Kwon G.S., Suwa S., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates. J Control Release 1994, 29:17-23.
    • (1994) J Control Release , vol.29 , pp. 17-23
    • Kwon, G.S.1    Suwa, S.2    Yokoyama, M.3    Okano, T.4    Sakurai, Y.5    Kataoka, K.6
  • 39
    • 0033233187 scopus 로고    scopus 로고
    • Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system
    • Yokoyama M., Okano T., Sakurai Y., Fukushima S., Okamoto K., Kataoka K. Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system. J Drug Target 1999, 7:171-186.
    • (1999) J Drug Target , vol.7 , pp. 171-186
    • Yokoyama, M.1    Okano, T.2    Sakurai, Y.3    Fukushima, S.4    Okamoto, K.5    Kataoka, K.6
  • 40
    • 78649968090 scopus 로고    scopus 로고
    • Nanotheranostics and image-guided drug delivery: current concepts and future directions
    • Lammers T., Kiessling F., Hennink W.E., Storm G. Nanotheranostics and image-guided drug delivery: current concepts and future directions. Mol Pharm 2010, 7:1899-1912.
    • (2010) Mol Pharm , vol.7 , pp. 1899-1912
    • Lammers, T.1    Kiessling, F.2    Hennink, W.E.3    Storm, G.4
  • 41
    • 34548655885 scopus 로고    scopus 로고
    • Polymer platforms for drug delivery and biomedical imaging
    • Lu Z.R., Ye F., Vaidya A. Polymer platforms for drug delivery and biomedical imaging. J Control Release 2007, 122:269-277.
    • (2007) J Control Release , vol.122 , pp. 269-277
    • Lu, Z.R.1    Ye, F.2    Vaidya, A.3
  • 44
    • 0344958757 scopus 로고    scopus 로고
    • Approaches and agents for imaging the vascular system
    • Bogdanov A.A., Lewin M., Weissleder R. Approaches and agents for imaging the vascular system. Adv Drug Deliv Rev 1999, 37:279-293.
    • (1999) Adv Drug Deliv Rev , vol.37 , pp. 279-293
    • Bogdanov, A.A.1    Lewin, M.2    Weissleder, R.3
  • 45
    • 3242802129 scopus 로고    scopus 로고
    • A gadolinium(III) complex of a carboxylic-phosphorus acid derivative of diethylenetriamine covalently bound to inulin, a potential macromolecular MRI contrast agent
    • Lebdusková P., Kotek J., Hermann P., Vander Elst L., Muller R.N., Lukes I., Peters J.A. A gadolinium(III) complex of a carboxylic-phosphorus acid derivative of diethylenetriamine covalently bound to inulin, a potential macromolecular MRI contrast agent. Bioconjug Chem 2004, 15:881-889.
    • (2004) Bioconjug Chem , vol.15 , pp. 881-889
    • Lebdusková, P.1    Kotek, J.2    Hermann, P.3    Vander Elst, L.4    Muller, R.N.5    Lukes, I.6    Peters, J.A.7
  • 46
    • 0033363494 scopus 로고    scopus 로고
    • Gadolinium(III) chelates as MRI contrast agents: structure, dynamics, and applications
    • Caravan P., Ellison J.J., McMurry T.J., Lauffer R.B. Gadolinium(III) chelates as MRI contrast agents: structure, dynamics, and applications. Chem Rev 1999, 99:2293-2352.
    • (1999) Chem Rev , vol.99 , pp. 2293-2352
    • Caravan, P.1    Ellison, J.J.2    McMurry, T.J.3    Lauffer, R.B.4
  • 48
    • 49949152181 scopus 로고    scopus 로고
    • Vascular permeability, vascular hyperpermeability and angiogenesis
    • Nagy J.A., Benjamin L., Zeng H., Dvorak A.M., Dvorak H.F. Vascular permeability, vascular hyperpermeability and angiogenesis. Angiogenesis 2008, 11:109-119.
    • (2008) Angiogenesis , vol.11 , pp. 109-119
    • Nagy, J.A.1    Benjamin, L.2    Zeng, H.3    Dvorak, A.M.4    Dvorak, H.F.5
  • 49
    • 0023788067 scopus 로고
    • Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules
    • Dvorak H.F., Nagy J.A., Dvorak J.T., Dvorak A.M. Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules. Am J Pathol 1988, 133:95-109.
    • (1988) Am J Pathol , vol.133 , pp. 95-109
    • Dvorak, H.F.1    Nagy, J.A.2    Dvorak, J.T.3    Dvorak, A.M.4
  • 50
    • 0029004025 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
    • Dvorak H.F., Brown L.F., Detmar M., DvorakReview A.M. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995, 146:1029-1039.
    • (1995) Am J Pathol , vol.146 , pp. 1029-1039
    • Dvorak, H.F.1    Brown, L.F.2    Detmar, M.3    DvorakReview, A.M.4
  • 51
    • 0026639806 scopus 로고
    • Angiogenesis
    • Folkman J., Shing Y. Angiogenesis. J Biol Chem 1992, 267:10931-10934.
    • (1992) J Biol Chem , vol.267 , pp. 10931-10934
    • Folkman, J.1    Shing, Y.2
  • 52
    • 84975525035 scopus 로고
    • Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis
    • Folkman J. Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. N Engl J Med 1995, 333:1757-1763.
    • (1995) N Engl J Med , vol.333 , pp. 1757-1763
    • Folkman, J.1
  • 53
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren L., O'Reilly M.S., Folkman J. Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat Med 1995, 1:149-153.
    • (1995) Nat Med , vol.1 , pp. 149-153
    • Holmgren, L.1    O'Reilly, M.S.2    Folkman, J.3
  • 54
    • 0034866792 scopus 로고    scopus 로고
    • Liposomes bearing polyethyleneglycol-coupled transferrin with intracellular targeting property to the solid tumors in vivo
    • Ishida O., Maruyama K., Tanahashi H., Iwatsuru M., Sasaki K., Eriguchi M., Yanagie H. Liposomes bearing polyethyleneglycol-coupled transferrin with intracellular targeting property to the solid tumors in vivo. Pharm Res 2001, 18:1042-1048.
    • (2001) Pharm Res , vol.18 , pp. 1042-1048
    • Ishida, O.1    Maruyama, K.2    Tanahashi, H.3    Iwatsuru, M.4    Sasaki, K.5    Eriguchi, M.6    Yanagie, H.7
  • 55
    • 0029039418 scopus 로고
    • Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier
    • Seymour L.W., Miyamoto Y., Maeda H., Brereton M., Strohalm J., Ulbrich K., Duncan R. Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier. Eur J Cancer 1995, 31A:766-770.
    • (1995) Eur J Cancer , vol.31 A , pp. 766-770
    • Seymour, L.W.1    Miyamoto, Y.2    Maeda, H.3    Brereton, M.4    Strohalm, J.5    Ulbrich, K.6    Duncan, R.7
  • 56
    • 67449084321 scopus 로고    scopus 로고
    • Preclinical and clinical studies of anticancer agent-incorporating polymer micelles
    • Matsumura Y., Kataoka K. Preclinical and clinical studies of anticancer agent-incorporating polymer micelles. Cancer Sci 2009, 100:572-579.
    • (2009) Cancer Sci , vol.100 , pp. 572-579
    • Matsumura, Y.1    Kataoka, K.2
  • 57
    • 57249084773 scopus 로고    scopus 로고
    • Polymeric micellar delivery systems in oncology
    • Matsumura Y. Polymeric micellar delivery systems in oncology. Jpn J Clin Oncol 2008, 38:793-802.
    • (2008) Jpn J Clin Oncol , vol.38 , pp. 793-802
    • Matsumura, Y.1
  • 58
    • 42649145864 scopus 로고    scopus 로고
    • Poly (amino acid) micelle nanocarriers in preclinical and clinical studies
    • Matsumura Y. Poly (amino acid) micelle nanocarriers in preclinical and clinical studies. Adv Drug Deliv Rev 2008, 60:899-914.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 899-914
    • Matsumura, Y.1
  • 59
    • 10844293438 scopus 로고    scopus 로고
    • Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin
    • Matsumura Y., Hamaguchi T., Ura T., Muro K., Yamada Y., Shimada Y., Shirao K., et al. Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin. Br J Cancer 2004, 91:1775-1781.
    • (2004) Br J Cancer , vol.91 , pp. 1775-1781
    • Matsumura, Y.1    Hamaguchi, T.2    Ura, T.3    Muro, K.4    Yamada, Y.5    Shimada, Y.6    Shirao, K.7
  • 60
    • 34447331464 scopus 로고    scopus 로고
    • A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation
    • Hamaguchi T., Kato K., Yasui H., Morizane C., Ikeda M., Ueno H., Muro K., et al. A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation. Br J Cancer 2007, 97:170-176.
    • (2007) Br J Cancer , vol.97 , pp. 170-176
    • Hamaguchi, T.1    Kato, K.2    Yasui, H.3    Morizane, C.4    Ikeda, M.5    Ueno, H.6    Muro, K.7
  • 61
    • 27144472720 scopus 로고    scopus 로고
    • Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats
    • Uchino H., Matsumura Y., Negishi T., Koizumi F., Hayashi T., Honda T., Nishiyama N., et al. Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats. Br J Cancer 2005, 93:678-687.
    • (2005) Br J Cancer , vol.93 , pp. 678-687
    • Uchino, H.1    Matsumura, Y.2    Negishi, T.3    Koizumi, F.4    Hayashi, T.5    Honda, T.6    Nishiyama, N.7
  • 62
    • 33748289523 scopus 로고    scopus 로고
    • NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel
    • Negishi T., Koizumi F., Uchino H., Kuroda J., Kawaguchi T., Naito S., Matsumura Y. NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel. Br J Cancer 2006, 95:601-606.
    • (2006) Br J Cancer , vol.95 , pp. 601-606
    • Negishi, T.1    Koizumi, F.2    Uchino, H.3    Kuroda, J.4    Kawaguchi, T.5    Naito, S.6    Matsumura, Y.7
  • 63
    • 20944450473 scopus 로고    scopus 로고
    • NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel
    • Hamaguchi T., Matsumura Y., Suzuki M., Shimizu K., Goda R., Nakamura I., Nakatomi I., et al. NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel. Br J Cancer 2005, 92:1240-1246.
    • (2005) Br J Cancer , vol.92 , pp. 1240-1246
    • Hamaguchi, T.1    Matsumura, Y.2    Suzuki, M.3    Shimizu, K.4    Goda, R.5    Nakamura, I.6    Nakatomi, I.7
  • 64
    • 34547673162 scopus 로고    scopus 로고
    • Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity
    • Cabral H., Nishiyama N., Kataoka K. Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity. J Control Release 2007, 121:146-155.
    • (2007) J Control Release , vol.121 , pp. 146-155
    • Cabral, H.1    Nishiyama, N.2    Kataoka, K.3
  • 65
    • 33750549679 scopus 로고    scopus 로고
    • Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors
    • Koizumi F., Kitagawa M., Negishi T., Onda T., Matsumoto S., Hamaguchi T., Matsumura Y. Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors. Cancer Res 2006, 66:10048-10056.
    • (2006) Cancer Res , vol.66 , pp. 10048-10056
    • Koizumi, F.1    Kitagawa, M.2    Negishi, T.3    Onda, T.4    Matsumoto, S.5    Hamaguchi, T.6    Matsumura, Y.7
  • 66
    • 37349080672 scopus 로고    scopus 로고
    • Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer
    • Kim D.W., Kim S.Y., Heo D.S., Kim H.K., Kim S.W., Shin S.W., Kim J.S., et al. Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer. Ann Oncol 2007, 18:2009-2014.
    • (2007) Ann Oncol , vol.18 , pp. 2009-2014
    • Kim, D.W.1    Kim, S.Y.2    Heo, D.S.3    Kim, H.K.4    Kim, S.W.5    Shin, S.W.6    Kim, J.S.7
  • 67
    • 39749178252 scopus 로고    scopus 로고
    • Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer
    • Lee K.S., Chung H.C., Ro J., Im S.A., Park Y.H., Kim C.S., Kim S.B., et al. Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer. Breast Cancer Res Treat 2008, 108:241-250.
    • (2008) Breast Cancer Res Treat , vol.108 , pp. 241-250
    • Lee, K.S.1    Chung, H.C.2    Ro, J.3    Im, S.A.4    Park, Y.H.5    Kim, C.S.6    Kim, S.B.7
  • 69
    • 1942470679 scopus 로고    scopus 로고
    • Phase I dose escalation and pharmacokinetic study of pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer
    • Danson S., Alakhov V., Ranson M., Ferry D., Margison J., Kerr D., Jowle D., et al. Phase I dose escalation and pharmacokinetic study of pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer. Br J Cancer 2004, 90:2085-2091.
    • (2004) Br J Cancer , vol.90 , pp. 2085-2091
    • Danson, S.1    Alakhov, V.2    Ranson, M.3    Ferry, D.4    Margison, J.5    Kerr, D.6    Jowle, D.7
  • 70
    • 39149143045 scopus 로고    scopus 로고
    • Anti-tumor effect of all-trans retinoic acid loaded polymeric micelles in solid tumor bearing mice
    • Chansri N., Kawakami S., Yokoyama M., Yamamoto T., Charoensit P., Hashida M. Anti-tumor effect of all-trans retinoic acid loaded polymeric micelles in solid tumor bearing mice. Pharm Res 2008, 25:428-434.
    • (2008) Pharm Res , vol.25 , pp. 428-434
    • Chansri, N.1    Kawakami, S.2    Yokoyama, M.3    Yamamoto, T.4    Charoensit, P.5    Hashida, M.6
  • 71
    • 42749092002 scopus 로고    scopus 로고
    • Block copolymer design for stable encapsulation of N-(4-hydroxyphenyl)retinamide into polymeric micelles in mice
    • Okuda T., Kawakami S., Yokoyama M., Yamamoto T., Yamashita F., Hashida M. Block copolymer design for stable encapsulation of N-(4-hydroxyphenyl)retinamide into polymeric micelles in mice. Int J Pharm (Note) 2008, 357:318-322.
    • (2008) Int J Pharm (Note) , vol.357 , pp. 318-322
    • Okuda, T.1    Kawakami, S.2    Yokoyama, M.3    Yamamoto, T.4    Yamashita, F.5    Hashida, M.6
  • 73
    • 67349089025 scopus 로고    scopus 로고
    • Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release control
    • Satoh T., Higuchi Y., Kawakami S., Hashida M., Kagechika H., Shudo K., Yokoyama M. Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release control. J Control Release 2009, 136:187-195.
    • (2009) J Control Release , vol.136 , pp. 187-195
    • Satoh, T.1    Higuchi, Y.2    Kawakami, S.3    Hashida, M.4    Kagechika, H.5    Shudo, K.6    Yokoyama, M.7
  • 74
    • 77954672019 scopus 로고    scopus 로고
    • Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts
    • Yokosawa M., Sonoda Y., Sugiyama S., Saito R., Yamashita Y., Nishihara M., Satoh T., et al. Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts. Tohoku J Exp Med 2010, 221:257-264.
    • (2010) Tohoku J Exp Med , vol.221 , pp. 257-264
    • Yokosawa, M.1    Sonoda, Y.2    Sugiyama, S.3    Saito, R.4    Yamashita, Y.5    Nishihara, M.6    Satoh, T.7
  • 75
    • 65949110136 scopus 로고    scopus 로고
    • Therapeutic efficacy of a polymeric micellar doxorubicin infused by convection-enhanced delivery against intracranial 9L brain tumor models
    • Inoue T., Yamashita Y., Nishihara M., Sugiyama S., Sonoda, Kumabe T., Yokoyama M., et al. Therapeutic efficacy of a polymeric micellar doxorubicin infused by convection-enhanced delivery against intracranial 9L brain tumor models. Neuro-Oncology 2009, 11:151-157.
    • (2009) Neuro-Oncology , vol.11 , pp. 151-157
    • Inoue, T.1    Yamashita, Y.2    Nishihara, M.3    Sugiyama, S.4    Sonoda5    Kumabe, T.6    Yokoyama, M.7
  • 76
    • 33847635618 scopus 로고    scopus 로고
    • Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling
    • Kano M.R., Bae Y., Iwata C., Morishita Y., Yashiro M., Oka M., Fujii T., et al. Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling. Proc Natl Acad Sci USA 2007, 104:3460-3465.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 3460-3465
    • Kano, M.R.1    Bae, Y.2    Iwata, C.3    Morishita, Y.4    Yashiro, M.5    Oka, M.6    Fujii, T.7
  • 77
    • 70649115375 scopus 로고    scopus 로고
    • Increase in tumor permeability following TGF-b type I receptor inhibitor treatment observed by dynamic contrast-enhanced MRI
    • Minowa T., Kawano K., Kuribayashi H., Shiraishi K., Sugino T., Hattori Y., Yokoyama M., et al. Increase in tumor permeability following TGF-b type I receptor inhibitor treatment observed by dynamic contrast-enhanced MRI. Br J Cancer 2009, 101:1884-1890.
    • (2009) Br J Cancer , vol.101 , pp. 1884-1890
    • Minowa, T.1    Kawano, K.2    Kuribayashi, H.3    Shiraishi, K.4    Sugino, T.5    Hattori, Y.6    Yokoyama, M.7
  • 78
    • 70649088695 scopus 로고    scopus 로고
    • Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application
    • Seki T., Fang J., Maeda H. Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application. Cancer Sci 2009, 100:2426-2430.
    • (2009) Cancer Sci , vol.100 , pp. 2426-2430
    • Seki, T.1    Fang, J.2    Maeda, H.3
  • 79
    • 77951617297 scopus 로고    scopus 로고
    • The combretastatin derivative cderiv, a vascular disrupting agent, enables polymeric nanomicelles to accumulate in microtumors
    • Hori K., Nishihara M., Yokoyama M. The combretastatin derivative cderiv, a vascular disrupting agent, enables polymeric nanomicelles to accumulate in microtumors. J Pharm Sci 2010, 99:2914-2925.
    • (2010) J Pharm Sci , vol.99 , pp. 2914-2925
    • Hori, K.1    Nishihara, M.2    Yokoyama, M.3


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