Large-scale synthesis of a substituted d -phenylalanine using asymmetric hydrogenation

Organic Process Research and Development

Volumn 15, Issue 5, 2011, Pages 1163-1171

  Fox, Martin E ^a   Jackson, Mark ^a   Meek, Graham ^a   Willets, Matthew ^b  

^a Unit 410 Cambridge Science Park   (United Kingdom)

^b Dr Reddy's Laboratories EU Limited   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC HYDROGENATION; BASIC HYDROLYSIS; BOC GROUP; D-PHENYLALANINE; DEHYDROPHENYLALANINE; ENAMIDES; ENANTIOMERIC EXCESS; LARGE SCALE SYNTHESIS; MESYLATION; METHYL ESTERS; MONOREDUCTION; PHARMACEUTICAL INTERMEDIATES; RING OPENING; SCALE-UP; SYNTHETIC ROUTES;

ACETYLATION; ALDEHYDES; AMINO ACIDS; METHANOL; ORGANIC COMPOUNDS; RHODIUM;

HYDROGENATION;

EID: 80053001962     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op200129m     Document Type: Article

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