Mutation of the transcription factor LEAFY COTYLEDON 2 alters the chemical composition of Arabidopsis seeds, decreasing oil and protein content, while maintaining high levels of starch and sucrose in mature seeds

Journal of Plant Physiology

Volumn 168, Issue 16, 2011, Pages 1891-1900

  Angeles Núñez, Juan Gabriel ^a   Tiessen, Axel ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Lec2 1; Sink source; Starch; T DNA insertion

Indexed keywords

ARABIDOPSIS PROTEIN; FATTY ACID; LEC2 PROTEIN, ARABIDOPSIS; STARCH; SUCROSE; TRANSCRIPTION FACTOR;

ARABIDOPSIS; ARTICLE; CARBOHYDRATE METABOLISM; GENE EXPRESSION REGULATION; GENETICS; GERMINATION; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY; PLANT LEAF; PLANT SEED; TIME;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; CARBOHYDRATE METABOLISM; FATTY ACIDS; GERMINATION; MUTAGENESIS, INSERTIONAL; PLANT LEAVES; SEEDS; STARCH; SUCROSE; TIME FACTORS; TRANSCRIPTION FACTORS;

ARABIDOPSIS;

EID: 80052959930     PISSN: 01761617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jplph.2011.05.003     Document Type: Article

References (48)

1. Andriotis V.M.E., Pike M.J., Kular B., Rawsthorne S., Smith A.M. Starch turnover in developing oilseed embryos. New Phytol 2010, 187:791-804.
2. Angeles-Nuñez J.G., Tiessen A. Arabidopsis sucrose synthase 2 and 3 modulate metabolic homeostasis and direct carbon towards starch synthesis in developing seeds. Planta 2010, 232:701-718.
3. Barratt D.H.P., Derbyshire P., Findlay K., Pike M., Wellner N., Lunn J., et al. Normal growth of Arabidopsis requires cytosolic invertase but not sucrose synthase. Proc Natl Acad Sci USA 2009, 106:13124-13129.
4. Baud S., Boutin J.P., Miquel M., Lepiniec L., Rochat C. An integrated overview of seed development in Arabidopsis thaliana ecotype ws. Plant Physiol Biochem 2002, 40:151-160.
5. Baud S., Mendoza M.S., To A., Harscoet E., Lepiniec L., Dubreucq B. Wrinkled1 specifies the regulatory action of leafy cotyledon2 towards fatty acid metabolism during seed maturation in Arabidopsis. Plant J 2007, 50:825-838.
6. Baud S., Wuilleme S., To A., Rochat C., Lepiniec L. Role of wrinkled1 in the transcriptional regulation of glycolytic and fatty acid biosynthetic genes in Arabidopsis. Plant J 2009, 60:933-947.
7. Bechtold N., Ellis J., Pelletier G. In-planta Agrobacterium mediated gene transfer by infiltration of adult Arabidopsis thaliana plants. Cr Acad Sci Iii-Vie 1993, 316:1194-1199.
8. Bewley J.D., Black M. Seeds: physiology of development and germination 1994, Plenum, New York.
9. Cernac A., Benning C. Wrinkled1 encodes an ap2/ereb domain protein involved in the control of storage compound biosynthesis in Arabidopsis. Plant J 2004, 40:575-585.
10. Chourey P., Jain M., Li Q.B., Carlson S. Genetic control of cell wall invertases in developing endosperm of maize. Planta 2006, 223:159-167.
11. daSilva P.M.F.R., Eastmond P.J., Hill L.M., Smith A.M., Rawsthorne S. Starch metabolism in developing embryos of oilseed rape. Planta 1997, 203:480-487.
12. Eastmond P.J., Graham I.A. Re-examining the role of the glyoxylate cycle in oilseeds. Trends Plant Sci 2001, 6:72-77.
13. Eastmond P.J., Germain V., Lange P.R., Bryce J.H., Smith S.M., Graham I.A. Postgerminative growth and lipid catabolism in oilseeds lacking the glyoxylate cycle. Proc Natl Acad Sci USA 2000, 97:5669-5674.
14. Fait A., Angelovici R., Less H., Ohad I., Urbanczyk-Wochniak E., Fernie A.R., et al. Arabidopsis seed development and germination is associated with temporally distinct metabolic switches. Plant Physiol 2006, 142:839-854.
15. FAO Chemical composition and nutritional value of maize. Maize in human nutrition 1992, Food and Agricultural Organization of the United Nations, Rome. 25 FFaNSN (Ed.).
16. Focks N., Benning C. Wrinkled1 A novel, low-seed-oil mutant of Arabidopsis with a deficiency in the seed-specific regulation of carbohydrate metabolism. Plant Physiol 1998, 118:91-101.
17. Gutierrez L., Van Wuytswinkel O., Castelain M., Bellini C. Combined networks regulating seed maturation. Trends Plant Sci 2007, 12:294-300.
18. Harada J.J. Role of Arabidopsis leafy cotyledon genes in seed development. J Plant Physiol 2001, 158:405-409.
19. Herbers K., Sonnewald U. Molecular determinants of sink strength. Curr Opin Plant Biol 1998, 1:207-216.
20. Hills M.J. Control of storage-product synthesis in seeds. Curr Opin Plant Biol 2004, 7:302-308.
21. Jain M., Chourey P.S., Li Q.B., Pring D.R. Expression of cell wall invertase and several other genes of sugar metabolism in relation to seed development in sorghum (Sorghum bicolor). J Plant Physiol 2008, 165:331-344.
22. Jofuku K.D., Omidyar P.K., Gee Z., Okamuro J.K. Control of seed mass and seed yield by the floral homeotic gene apetala2. Proc Natl Acad Sci USA 2005, 102:3117-3122.
23. Kroj T., Savino G., Valon C., Giraudat J., Parcy F. Regulation of storage protein gene expression in Arabidopsis. Development 2003, 130:6065-6073.
24. Kwong R.W., Bui A.Q., Lee H., Kwong L.W., Fischer R.L., Goldberg R.B., et al. Leafy cotyledon1-like defines a class of regulators essential for embryo development. Plant Cell 2003, 15:5-18.
25. Lin Y., Cluette-Brown J.E., Goodman H.M. The peroxisome deficient Arabidopsis mutant sse1 exhibits impaired fatty acid synthesis. Plant Physiol 2004, 135:814-827.
26. Lin Y., Ulanov A.V., Lozovaya V., Widholm J., Zhang G.R., Guo J.H., et al. Genetic and transgenic perturbations of carbon reserve production in Arabidopsis seeds reveal metabolic interactions of biochemical pathways. Planta 2006, 225:153-164.
27. Lotan T., Ohto M., Yee K.M., West M.A.L., Lo R., Kwong R.W., et al. Arabidopsis leafy cotyledon1 is sufficient to induce embryo development in vegetative cells. Cell 1998, 93:1195-1205.
28. Luerssen K., Kirik V., Herrmann P., Misera S. Fusca3 encodes a protein with a conserved vp1/abi3-like b3 domain which is of functional importance for the regulation of seed maturation in Arabidopsis thaliana. Plant J 1998, 15:755-764.
29. Meinke D.W. A homeotic mutant of Arabidopsis thaliana with leafy cotyledons. Science 1992, 258:1647-1650.
30. Meinke D.W., Franzmann L.H., Nickle T.C., Yeung E.C. Leafy cotyledon mutants of Arabidopsis. Plant Cell 1994, 6:1049-1064.
31. Mendoza M.S., Dubreucq B., Miquel M., Caboche M., Lepiniec L. Leafy cotyledon 2 activation is sufficient to trigger the accumulation of oil and seed specific mRNAs in Arabidopsis leaves. FEBS Lett 2005, 579:4666-4670.
32. Morley-Smith E.R., Pike M.J., Findlay K., Koeckenberger W., Hill L.M., Smith A.M., et al. The transport of sugars to developing embryos is not via the bulk endosperm in oilseed rape seeds. Plant Physiol 2008, 147:2121-2130.
33. North H., Baud S., Debeaujon I., Dubos C., Dubreucq B., Grappin P., et al. Arabidopsis seed secrets unravelled after a decade of genetic and omics-driven research. Plant J 2010, 61:971-981.
34. Ohto M., Fischer R.L., Goldberg R.B., Nakamura K., Harada J.J. Control of seed mass by apetala2. Proc Natl Acad Sci USA 2005, 102:3123-3128.
35. Rider S.D., Henderson J.T., Jerome R.E., Edenberg H.J., Romero-Severson J., Ogas J. Coordinate repression of regulators of embryonic identity by pickle during germination in Arabidopsis. Plant J 2003, 35:33-43.
36. Ruuska S.A., Girke T., Benning C., Ohlrogge J.B. Contrapuntal networks of gene expression during Arabidopsis seed filling. Plant Cell 2002, 14:1191-1206.
37. Santos-Mendoza M., Dubreucq B., Baud S., Parcy F., Caboche M., Lepiniec L. Deciphering gene regulatory networks that control seed development and maturation in Arabidopsis. Plant J 2008, 54:608-620.
38. Schmid M., Davison T.S., Henz S.R., Pape U.J., Demar M., Vingron M., et al. A gene expression map of Arabidopsis thaliana development. Nat Genet 2005, 37:501-506.
39. Stone S.L., Braybrook S.A., Paula S.L., Kwong L.W., Meuser J., Pelletier J., et al. Arabidopsis leafy cotyledon2 induces maturation traits and auxin activity: implications for somatic embryogenesis. Proc Natl Acad Sci USA 2008, 105:3151-3156.
40. Stone S.L., Kwong L.W., Yee K.M., Pelletier J., Lepiniec L., Fischer R.L., et al. Leafy cotyledon2 encodes a b3 domain transcription factor that induces embryo development. Proc Natl Acad Sci USA 2001, 98:11806-11811.
41. Tiessen A., Hendriks J.H.M., Stitt M., Branscheid A., Gibon Y., Farre E.M., et al. Starch synthesis in potato tubers is regulated by post-translational redox modification of ADP-glucose pyrophosphorylase: a novel regulatory mechanism linking starch synthesis to the sucrose supply. Plant Cell 2002, 14:2191-2213.
42. Tiessen A., Prescha K., Branscheid A., Palacios N., McKibbin R., Halford N.G., et al. Evidence that SNF1-related kinase and hexokinase are involved in separate sugar-signalling pathways modulating post-translational redox activation of ADP-glucose pyrophosphorylase in potato tubers. Plant J 2003, 35:490-500.
43. To A., Valon C., Savino G., Guilleminot J., Devic M., Giraudat J., et al. A network of local and redundant gene regulation governs Arabidopsis seed maturation. Plant Cell 2006, 18:1642-1651.
44. Turner N.C., Furbank R.T., Berger J.D., Gremigni P., Abbo S., Leport L. Seed size is associated with sucrose synthase activity in developing cotyledons of chickpea. Crop Sci 2009, 49:621-627.
45. Weber H., Borisjuk L., Wobus U. Controlling seed development and seed size in Vicia faba-a role for seed coat-associated invertases and carbohydrate state. Plant J 1996, 10:823-834.
46. Weber H., Borisjuk L., Wobus U. Molecular physiology of legume seed development. Annu Rev Plant Biol 2005, 56:253-279.
47. Weber H., Heim U., Golombek S., Borisjuk L., Manteuffel R., Wobus U. Expression of a yeast-derived invertase in developing cotyledons of vicia narbonensis alters the carbohydrate state and affects storage functions. Plant J 1998, 16:163-172.
48. Welham T., Pike J., Horst I., Flemetakis E., Katinakis P., Kaneko T., et al. A cytosolic invertase is required for normal growth and cell development in the model legume, lotus japonicus. J Exp Bot 2009, 60:3353-3365.