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European Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2011, Pages 4227-4237

Chemical synthesis and evaluation of 17α-alkylated derivatives of estradiol as inhibitors of steroid sulfatase

(2) Fournier, Diane a Poirier, Donald a

a LAVAL UNIVERSITY (Canada)

Author keywords

Cancer; Estrogen; Grignard reagent; Kagan reagent; Samarium Barbier reaction; Steroid sulfatase inhibitors

Indexed keywords

(17BETA) 17 (2,3,4,5,6 PENTAFLUOROBENZYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 (3 BENZYLOXYBENZYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 (3 IODOBENZYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 (3 TERT BUTYLBENZYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 (3 TRIFLUOROMETHYLBENZYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 (3,5 DIBROMOBENZYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 (4 BROMOBENZYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 (4 IODOBENZYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 (4 TRIFLUOROMETHYLBENZYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 (CYCLOHEXYLMETHYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 (PYRIDIN 3 YLMETHYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 [3 (DIBENZYLAMINO)BENZYL] ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 [3,5 BIS(BENZYLOXY)BENZYL] ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 [3,5 BIS(TERT BUTYL)BENZYL] ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA) 17 [3,5 BIS(TRIFLUOROMETHYL)BENZYL] ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA)17 (2 FURYLMETHYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; (17BETA)17 (4 METHYL 2 THIENYL) ESTRA 1(10),2,4 TRIENE 3,17 DIOL DERIVATIVE; 17ALPHA ESTRADIOL; 3 DIBENZYLAMINOBENZYL BROMIDE DERIVATIVE; 3 TERT BUTYLBENZYL BROMIDE DERIVATIVE; 3,5 DI BROMOBENZYL BROMIDE DERIVATIVE; 3,5 DI TERT BUTYLBENZYL BROMIDE DERIVATIVE; 3,5 DIBENZYLOXYBENZYL BROMIDE DERIVATIVE; BENZYL DERIVATIVE; CARBONYL DERIVATIVE; ESTRONE; ETHYLENE OXIDE; SAMARIUM; STERYL SULFATASE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; STOICHIOMETRY; STRUCTURE ACTIVITY RELATION;

ALKYLATION; CELL LINE; ENZYME INHIBITORS; ESTRADIOL; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; SPECTROPHOTOMETRY, INFRARED; STERYL-SULFATASE;

EID: 80052939840 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2011.06.027 Document Type: Article

Times cited : (15)

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