Impaired fitness of Mycobacterium tuberculosis resistant isolates in a cell culture model of murine macrophages

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 10, 2011, Pages 2277-2280

  Rey Jurado, Emma ^a   Tudó, Griselda ^a   Borrell, Sònia ^a,f   Alcaide, Fernando ^b   Coll, Pere ^c   Español, Montserrat ^c   Martín Casabona, Núria ^d   Mick, Virginie ^b,g   Montemayor, Michel ^c   Moure, Raquel ^b   Salvadó, Margarita ^e   Vicente, Eva ^e   González Martín, Julià ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^d HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^e Laboratori de Refere'ncia de Catalunya   (Spain)

^f SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^g FRENCH AGENCY FOR FOOD   (France)

Author keywords

Inha mutation; Katg mutation; M. tuberculosis; Macrophage cultures; RpoB mutation

Indexed keywords

ISONIAZID; KATG PROTEIN; MUTANT PROTEIN; SERINE; THREONINE;

ANIMAL CELL; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; GENE MUTATION; MACROPHAGE; MICROBIOLOGICAL PARAMETERS; MULTIDRUG RESISTANCE; MYCOBACTERIAL GROWTH RATIO; MYCOBACTERIAL PENETRATION INDEX; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE;

ANIMALS; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; CATALASE; CELL LINE; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HUMANS; ISONIAZID; MACROPHAGES; MICE; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; OXIDOREDUCTASES;

EID: 80052906815     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkr288     Document Type: Article

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