Polymers for colon targeted drug delivery

Indian Journal of Pharmaceutical Sciences

Volumn 72, Issue 6, 2010, Pages 689-696

  Rajpurohit, H ^a   Sharma, P ^a   Sharma, S ^a   Bhandari, A ^a  

^a Jodhpur National University   (India)

Author keywords

Biodegradable polymers; colon targeted delivery; controlled delivery; polysaccharides

Indexed keywords

ALGAROBA; AMYLOSE; CHITOSAN; CHONDROITIN SULFATE; CYCLODEXTRIN; DEXTRAN; ETHYL CELLULOSE; GUAR GUM; INULIN; PECTIN; POLYMER;

BIODEGRADABILITY; COLON; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG FORMULATION; DRUG RELEASE; HUMAN; QUANTITATIVE ANALYSIS; REVIEW; SMALL INTESTINE; STOMACH; STRUCTURE ANALYSIS;

EID: 80052885356     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.84576     Document Type: Review

References (41)

1. Wilson CG, Mukherji G, Sha HK. Biopolymers and Colonic Delivery. In: Rathbone MJ, Had graft J, Roberts MS, Lane ME, editors. Modified-release Drug Delivery Technology. 2nd ed. Vol. 1. New York: Informa Healthcare; 2008. p. 295-309.
2. Jose S, Dhanya K, Cinu TA, Litty J, Chacko AJ. Colon Targeted drug delivery: Different approaches. J Young Pharm 2009;1:13-9.
3. Kumar RS, Kumar M, Ganesh GN, Jawahar N, Nagasamyvenkatesh D, Senthil V, et al. Formulation and evaluation of pectin-hydroxypropyl methylcellulose coated curcumin pellets for colon delivery. Asian J Pharm 2009:3;138-42.
4. Vyas SP, Khar RK. Systems for colon specific delivery. In: Vyas SP, Khar RK editors. Controlled drug delivery: Concept and advantages. 1st ed. Delhi: Vallabh Prakashan; 2002. p. 218-56.
5. Jain S, Jain NK. Polymers in Pharmaceutical Sciences. In: Jain NK, editor. Pharmaceutical Product Development. 1st ed. New Delhi: CBS Publisher and Distributor; 2006. p. 585-621.
6. Shirwaikar A, Shirwaikar AN, Prabu SL, Kumar GA. Herbal Excipients in Novel Drug Delivery Systems. Indian J Pharm Sci 2008;70:415-22.
7. Available from: http://en.wikipedia.org/wiki/Guar-gum
8. Wong D, Larrabee S, Clifford K, Tremblay J, Friend DR. USP Dissolution Apparatus III (reciprocating cylinder) for screening of guar-based colonic delivery formulations. J Control Release 1997;47:173-9. (Pubitemid 27212344)
9. Krishnaiah YS, Satyanarayana S, Prasad YV, Rao SN. Gamma Scientigraphic studies on guar-gum matrix tablet for colonic drug delivery in healthy human volunteers. J Control Release 1998;55:245-52. (Pubitemid 28477615)
10. Krishnaiah YS, Rajua PV, Kumarb BD, Satyanarayanaa V, Karthikeyana RS, Bhaskara P. Pharmacokinetic evaluation of guar gum-based colon-targeted drug delivery systems of mebendazole in healthy volunteers. J Control Release 2003;88:95-103. (Pubitemid 36173955)
11. Ji CM, Xu HN, Wu W. Guar Gum as Potential Film Coating Material for Colon-specific Delivery of Fluorouracil. J Biomat Appl 2009;23:311-29.
12. Krishnaiah YS, Satyanarayana S, Prasad YV. Studies of guar-gum compression coated 5-aminosalicylic acid tablet for colonic specific drug delivery. Drug Develop Ind Pharm 1999;25:651-7. (Pubitemid 29186298)
13. Ravi V, Kumar TM, Siddaramaiah. Novel colon targeted drug delivery system using natural polymers. Indian J Pharm Sci 2008;70:111-3. (Pubitemid 351670583)
14. Sriamornsak P, Prakongpan S, Puttipipatkhachoran S, Kennedy RA. Development of sustained release theophylline pallets coated with calcium pectanate. J Control Release 1997;47:221-32. (Pubitemid 27220206)
15. Dupuis G, Chambin O, Genelot C, Champion D, Pourcelot Y. Colonic drug delivery: Influence of cross linking agent on pectin beads properties And role of capsule shell type. Drug Dev Ind Pharm 2006;32:847-55. (Pubitemid 44266769)
16. Lee CM, Kim DW, Lee HC, Lee KY. Pectin microspheres for oral colon delivery: Preparation using spray drying method and in vitro release of indomethacin. Biotech Bioproc Eng 2004;9:191-5.
17. Momin M, Pundarikakshudu K, Nagori SA. Design and development of mixed film of pectin: ethyl cellulose for colon specific drug delivery of sennosides and triphala. Indian J Pharm Sci 2008;70:338-43.
18. Wei H, Qing D, De-Ying C, Bai X, Li-Fang F. In vitro and in vivo studies of pectin/ethylcellulose film-coated pellets of 5-fluorouracil for colonic targeting. J Pharm Pharmacol 2008;60:35-44.
19. Jain A, Gupta Y, Jain SK. Perspectives of biodegradable natural polysaccharides for site specific delivery to the colon. J Pharm Pharm Sci 2007;10:86-128. (Pubitemid 46692379)
20. Chourasia MK, Jain SK. Pharmaceutical approaches to colon targeted drug delivery systems. J Pharm Pharm Sci 2003;6:33-66. (Pubitemid 37207241)
21. Rubinstein A, Nakar D, Sintov A. Colonic drug delivery: Enhanced release of indomethacin from cross linked chondroitin matrix in rat cecal content. Pharm Res 1992;9:276-8.
22. Rubinstein A, Nakar D, Sintov A. Chondroitin sulfate: A potential biodegradable carrier for colon-specific drug delivery. Int J Pharm 1992;84:141-50.
23. Amrutkar JR, Gattani SG. Chitosan-Chondroitin Sulfate Based Matrix Tablets for Colon Specific Delivery of Indomethacin. AAPS PharmSciTech 2009;10:670-7.
24. Cavalcanti OA, Silva CC, Pineda EG, Hechenleitner AW. Synthesis and characterization of phosphated crosslinked chondroitin sulfate: Potencial ingredient for specific drug delivery. Acta Farmaceutica Bonaerense 2005;24:234-8. (Pubitemid 41076213)
25. Ahmad S, Tester RF, Corbett A, Karkalas J. Dextran and 5-aminosalicylic acid conjugates: Synthesis, characterisation and enzymic hydrolysis. Carbohydr Res 2006;341:2694-701. (Pubitemid 44572199)
26. Hovgaard L, Brondsted H. Dextran hydrogels for colon-specific drug delivery. J Control Release 1995;36:159-66.
27. McLeod AD, Friend DR, Tozer TN. Glucocorticoid-dextran conjugates as potential prodrugs for colon-specific delivery: Hydrolysis in rat gastrointestinal tract contents. J Pharm Sci 2006;83:1284-8.
28. Lorenzo-Lamosa ML, Lopez CR, Vila-Jato JL, Alonso MJ. Design of microencapsulated chitosan microspheres for colonic drug delivery. J Control Release 1998;52:109-18. (Pubitemid 28123178)
29. Tozakia H, Odoribaa T, Okadaa N, Fujitaa T, Terabeb A, Suzuki T, et al. Chitosan capsules for colon-specific drug delivery: Enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats. J Control Release 2002;82:51-61. (Pubitemid 34775047)
30. Shu XZ, Zhu KJ, Song W. Novel pH-sensitive citrate cross-linked chitosan film for drug controlled release. Int J Pharm 2001;212:19-28. (Pubitemid 32121947)
31. Zhang H, Alsarra IA, Neau SH. An in vitro evaluation of a chitosan-containing multiparticulate system for macromolecule delivery to the colon. Int J Pharm 2002;239:197-205. (Pubitemid 34615809)
32. Shimono N, Takatori T, Ueda M, Mori M, Higashi Y, Nakamura Y. Chitosan dispersed system for colon-specific drug delivery. Int J Pharm 2002;245:45-54. (Pubitemid 35299890)
33. Orienti I, Cerchiara T, Luppi B, Bigucci F, Zuccari G, Zecchi V. Influence of different chitosan salts on the release of sodium diclofenac in colon-specific delivery. Int J Pharm 2002;238:51-9. (Pubitemid 34457875)
34. Minami K, Hirayama F, Uekama K. Colon-specific drug delivery based on a cyclodextrin prodrug: Release behavior of biphenylylacetic acid from its cyclodextrin conjugates in rat intestinal tracts after oral administration. J Pharm Sci 1998;87:715-20. (Pubitemid 28268570)
35. Vervoort L, Mooter GV, Augustijns P, Kinget R. Inulin hydrogels. I. Dynamic and equilibrium swelling properties. Int J Pharm 1998;172:127-35. (Pubitemid 28430250)
36. Vervoort L, Rombaut P, Mooter GV, Augustijns P, Kinget R. Inulin hydrogels. II. In vitro degradation study. Int J Pharm 1998;172:137-45. (Pubitemid 28430251)
37. Milojevic S, Newton JM, Cummings JH, Gibson GR, Botham RL, Ring SC, et al. Amylose as a coating for drug delivery to the colon: Preparation and in vitro evaluation using 5-aminosalicylic acid pellets. J Control Release 1996;38:75-84. (Pubitemid 26027181)
38. Milojevic S, Newton JM, Cummings JH, Gibson GR, Botham RL, Ring SC, et al. Amylose as a coating for drug delivery to the colon: Preparation and in vitro evaluation using glucose pellets. J Control Release 1996;38:85-94. (Pubitemid 26027182)
39. Lenaerts V, Dumoulin Y, Mateescu MA. Controlled release of theophylline from cross-linked amylose tablets. J Control Release 1991;15:39-46.
40. Cummings JH, Milojevic S, Harding M, Coward WA, Gibson GR, Botham RL, et al. In vivo studies of amylose and ethylcellulose coated [13C]glucose microspheres as a model for drug delivery to the colon. J Control Release 1996;40:123-31.
41. Raghavan CV, Muthulingam C, Amaladoss J, Jenita JL, Ravi TK. An in vitro and in vivo Investigation into the Suitability of Bacterially Triggered Delivery System for Colon Targeting. Chem Pharm Bull 2002;50:892-5. (Pubitemid 41694862)