On-chip constructive cell-network study (II): On-chip quasi-in vivo cardiac toxicity assay for ventricular tachycardia/fibrillation measurement using ring-shaped closed circuit microelectrode with lined-up cardiomyocyte cell network

Journal of Nanobiotechnology

Volumn 9, Issue , 2011, Pages

  Nomura, Fumimasa ^a   Kaneko, Tomoyuki ^a   Hattori, Akihiro ^a   Yasuda, Kenji ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE MICROCHAMBER; CARDIAC TOXICITY; CARDIOMYOCYTES; CELL NETWORK; CLOSED CIRCUIT; CLOSED-LOOP; EARLY AFTERDEPOLARIZATION; EXTRACELLULAR; FIELD POTENTIAL; HUMAN ETHER-A-GO-GO RELATED GENE (HERG); IN-VITRO; MICROELECTRODE CHIP; ON CHIPS; QT PROLONGATION; REPOLARIZATION; SCREENING ASSAYS; VENTRICULAR TACHYARRHYTHMIAS; VENTRICULAR TACHYCARDIA; WAVE FORMS;

CONVOLUTION; ETHERS; GENES; HEART; INDEPENDENT COMPONENT ANALYSIS; MICROELECTRODES; TOXICITY;

CELLS;

ASTEMIZOLE; HISTAMINE H1 RECEPTOR ANTAGONIST;

ARTICLE; CARDIOTOXICITY; ELECTRIC POTENTIAL; ELECTROCARDIOGRAM; HEART BEAT; HEART DEPOLARIZATION; HEART MUSCLE CELL; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; IN VIVO STUDY; MICROELECTRODE; NERVE CELL NETWORK; QT PROLONGATION; WAVEFORM; ANIMAL; CELL COMMUNICATION; CHEMICALLY INDUCED DISORDER; CULTURE TECHNIQUE; DRUG EFFECT; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; ASTEMIZOLE; CELL COMMUNICATION; CELL CULTURE TECHNIQUES; HISTAMINE H1 ANTAGONISTS, NON-SEDATING; MICE; MICROELECTRODES; MYOCYTES, CARDIAC; TACHYCARDIA, VENTRICULAR; VENTRICULAR FIBRILLATION;

EID: 80052857452     PISSN: None     EISSN: 14773155     Source Type: Journal    
DOI: 10.1186/1477-3155-9-39     Document Type: Article

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