Prognostic significance of liver stiffness for hepatocellular carcinoma and mortality in HBeAg-negative chronic hepatitis B

Journal of Viral Hepatitis

Volumn 18, Issue 10, 2011, Pages 738-744

  Fung, J ^a   Lai, C L ^a   Seto, W K ^a   Wong, D K H ^a   Yuen, M F ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

hepatitis B; hepatocellular carcinoma; liver stiffness

Indexed keywords

ADEFOVIR; ANTIVIRUS AGENT; ENTECAVIR; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; VIRUS DNA;

ADULT; AGED; ARTICLE; CANCER INCIDENCE; DEVICE; DISEASE COURSE; DISEASE EXACERBATION; ELASTOGRAPHY; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER FIBROSIS; LIVER FUNCTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; NON INVASIVE MEASUREMENT; PRIORITY JOURNAL; PROGNOSIS; RIGIDITY; VIRUS HEPATITIS; VIRUS LOAD;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, HEPATOCELLULAR; ELASTICITY IMAGING TECHNIQUES; FEMALE; HEPATITIS B E ANTIGENS; HEPATITIS B, CHRONIC; HUMANS; LIVER; MALE; MIDDLE AGED; PROGNOSIS; PROSPECTIVE STUDIES; SURVIVAL ANALYSIS; YOUNG ADULT;

EID: 80052856495     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2010.01355.x     Document Type: Article

References (26)

1. Yuen MF, Lai CL,. Treatment of chronic hepatitis B. Lancet Infect Dis 2001; 1 (4): 232-241.
2. Chu CM, Liaw YF,. Chronic hepatitis B virus infection acquired in childhood: special emphasis on prognostic and therapeutic implication of delayed HBeAg seroconversion. J Viral Hepat 2007; 14 (3): 147-152.
3. Chen CJ, Yang HI, Su J, et al. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 2006; 295 (1): 65-73. (Pubitemid 43042691)
4. Chu CM, Hung SJ, Lin J, Tai DI, Liaw YF,. Natural history of hepatitis B e antigen to antibody seroconversion in patients with normal serum aminotransferase levels. Am J Med 2004; 116 (12): 829-834. (Pubitemid 38721324)
5. Yuen MF, Tanaka Y, Shinkai N, et al. Risk for hepatocellular carcinoma with respect to hepatitis B virus genotypes B/C, specific mutations of enhancer II/core promoter/precore regions and HBV DNA levels. Gut 2008; 57 (1): 98-102.
6. Nguyen VT, Law MG, Dore GJ,. Hepatitis B-related hepatocellular carcinoma: epidemiological characteristics and disease burden. J Viral Hepat 2009; 16 (7): 453-463.
7. Yuen MF, Yuan HJ, Wong DK, et al. Prognostic determinants for chronic hepatitis B in Asians: therapeutic implications. Gut 2005; 54 (11): 1610-1614. (Pubitemid 41531781)
8. Yuen MF, Tanaka Y, Fong DY, et al. Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis B. J Hepatol 2009; 50 (1): 80-88.
9. Nguyen-Khac E, Chatelain D, Tramier B, et al. Assessment of asymptomatic liver fibrosis in alcoholic patients using fibroscan: prospective comparison with seven non-invasive laboratory tests. Aliment Pharmacol Ther 2008; 28 (10): 1188-1198.
10. Marcellin P, Ziol M, Bedossa P, et al. Non-invasive assessment of liver fibrosis by stiffness measurement in patients with chronic hepatitis B. Liver Int 2009; 29 (2): 242-247.
11. Castera L, Vergniol J, Foucher J, et al. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology 2005; 128 (2): 343-350. (Pubitemid 40439195)
12. Corpechot C, El Naggar A, Poujol-Robert A, et al. Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC. Hepatology 2006; 43 (5): 1118-1124. (Pubitemid 43724636)
13. Masuzaki R, Tateishi R, Yoshida H, et al. Prospective risk assessment for hepatocellular carcinoma development in patients with chronic hepatitis C by transient elastography. Hepatology 2009; 49 (6): 1954-1961.
14. Fung J, Lai CL, Yuen MF,. Hepatitis B and C virus-related carcinogenesis. Clin Microbiol Infect 2009; 15 (11): 964-970.
15. Liaw YF, Sung JJ, Chow WC, et al. Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med 2004; 351 (15): 1521-1531.
16. Yuen MF, Seto WK, Chow DH, et al. Long-term lamivudine therapy reduces the risk of long-term complications of chronic hepatitis B infection even in patients without advanced disease. Antivir Ther 2007; 12: 1295-1303.
17. Sandrin L, Fourquet B, Hasquenoph J, et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med Biol 2003; 29 (12): 1705-1713. (Pubitemid 38091720)
18. Lok AS, McMahon BJ,. Chronic hepatitis B: update 2009. Hepatology 2009; 50 (3): 661-662.
19. Fung J, Yuen MF, Yuen JC, Wong DK, Lai CL,. Low serum HBV DNA levels and development of hepatocellular carcinoma in patients with chronic hepatitis B: a case-control study. Aliment Pharmacol Ther 2007; 26 (3): 377-382. (Pubitemid 47063153)
20. Zhang BH, Yang BH, Tang ZY,. Randomized controlled trial of screening for hepatocellular carcinoma. J Cancer Res Clin Oncol 2004; 130 (7): 417-422.
21. McMahon BJ, Bulkow L, Harpster A, et al. Screening for hepatocellular carcinoma in Alaska natives infected with chronic hepatitis B: a 16-year population-based study. Hepatology 2000; 32 (4 Pt 1): 842-846.
22. Yuen MF, Cheng CC, Lauder IJ, et al. Early detection of hepatocellular carcinoma increases the chance of treatment: Hong Kong experience. Hepatology 2000; 31 (2): 330-335. (Pubitemid 30078596)
23. Hadziyannis SJ, Vassilopoulos D,. Hepatitis B e antigen-negative chronic hepatitis B. Hepatology 2001; 34 (4 Pt 1): 617-624. (Pubitemid 32927983)
24. Lai CL, Yuen MF,. The natural history and treatment of chronic hepatitis B: a critical evaluation of standard treatment criteria and end points. Ann Intern Med 2007; 147 (1): 58-61.
25. Shi JP, Fan JG, Wu R, et al. Prevalence and risk factors of hepatic steatosis and its impact on liver injury in Chinese patients with chronic hepatitis B infection. J Gastroenterol Hepatol 2008; 23: 1419-1425.
26. Fraquelli M, Rigamonti C, Casazze G, et al. Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease. Gut 2007; 56 (7): 968-973. (Pubitemid 46999083)