Cytotoxicity of synthetic cannabinoids found in "Spice" products: The role of cannabinoid receptors and the caspase cascade in the NG 108-15 cell line

Toxicology Letters

Volumn 207, Issue 1, 2011, Pages 12-17

  Tomiyama, Kenichi ^a   Funada, Masahiko ^a  

^a National Institute of Mental Health National Center of Neurology and Psychiatry   (Japan)

Author keywords

Apoptosis; Cannabinoid receptor; Cytotoxicity; Drug abuse; Spice; Synthetic cannabinoid

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID DERIVATIVE; CASPASE 3; CASPASE 3 INHIBITOR; CP 47947; LIPOCORTIN 5; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; GLIOMA CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING;

APOPTOSIS; CANNABINOIDS; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOHEXANOLS; CYSTEINE PROTEINASE INHIBITORS; DRUG INTERACTIONS; HUMANS; INDOLES; MICROSCOPY, FLUORESCENCE; OLIGOPEPTIDES; PIPERIDINES; PYRAZOLES; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2;

EID: 80052851618     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.08.021     Document Type: Article

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