DRhoGEF2 regulates cellular tension and cell pulsations in the amnioserosa during drosophila dorsal closure

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Azevedo, Dulce ^a   Antunes, Marco ^a   Prag, Soren ^a   Ma, Xiaoyan ^b   Hacker, Udo ^c   Brodland, G Wayne ^d   Hutson, M Shane ^b   Solon, Jerome ^e   Jacinto, Antonio ^a,f  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b VANDERBILT UNIVERSITY   (United States)

^c LUND UNIVERSITY   (Sweden)

^d UNIVERSITY OF WATERLOO   (Canada)

^e CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^f INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

DRHOGEF2 PROTEIN; DROSOPHILA PROTEIN; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN II; REGULATOR PROTEIN; UNCLASSIFIED DRUG; GREEN FLUORESCENT PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SHAR PEI PROTEIN, DROSOPHILA; SHAR-PEI PROTEIN, DROSOPHILA;

AMNIOSEROSAL CELL; ANIMAL CELL; ANIMAL TISSUE; APICAL CONSTRICTION; ARTICLE; CELL; CELL COUNT; CELL FUNCTION; CELL PULSATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; GASTRULATION; GENOTYPE; MORPHOGENESIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; ANIMAL; ANIMAL EMBRYO; CELL SHAPE; CONFOCAL MICROSCOPY; CYTOLOGY; DROSOPHILA MELANOGASTER; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; PRENATAL DEVELOPMENT; TRANSGENIC ANIMAL; VIDEORECORDING;

ACTOMYOSIN; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BODY PATTERNING; CELL SHAPE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; GREEN FLUORESCENT PROTEINS; MICROSCOPY, CONFOCAL; MUTATION; RHO GTP-BINDING PROTEINS; VIDEOTAPE RECORDING;

EID: 80052851014     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023964     Document Type: Article

References (28)

1. Gates J, Peifer M, (2005) Can 1000 reviews be wrong? Actin, alpha-Catenin, and adherens junctions. Cell 123: 769-772.
2. Halbleib JM, Nelson WJ, (2006) Cadherins in development: cell adhesion, sorting, and tissue morphogenesis. Genes & Dev 20: 3199-3214.
3. Sawyer JK, Harris NJ, Slep KC, Gaul U, Peifer M, (2009) The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction. J Cell Biol 186: 57-73.
4. Martin AC, (2010) Pulsation and stabilization: contractile forces that underlie morphogenesis. Dev Biol 341: 114-125.
5. Kiehart DP, Galbraith CG, Edwards KA, Rickoll WL, Montague RA, (2000) Multiple forces contribute to cell sheet morphogenesis for dorsal closure in Drosophila. J Cell Biol 149: 471-490.
6. Hutson MS, Tokutake Y, Chang MS, Bloor JW, Venakides S, et al. (2003) Forces for Morphogenesis Investigated with Laser Microsurgery and Quantitative Modeling. Science.
7. Young PE, Richman AM, Ketchum AS, Kiehart DP, (1993) Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function. Genes & Dev 7: 29-41.
8. Solon J, Kaya-Copur A, Colombelli J, Brunner D, (2009) Pulsed forces timed by a ratchet-like mechanism drive directed tissue movement during dorsal closure. Cell 137: 1331-1342.
9. Jacinto A, Wood W, Balayo T, Turmaine M, Martinez-Arias A, et al. (2000) Dynamic actin-based epithelial adhesion and cell matching during Drosophila dorsal closure. Curr Biol 10: 1420-1426.
10. Franke J, Montague R, Kiehart D, (2005) Nonmuscle Myosin II Generates Forces that Transmit Tension and Drive Contraction in Multiple Tissues during Dorsal Closure. Curr Biol 15: 2208-2221.
11. Ma X, Lynch HE, Scully PC, Hutson MS, (2009) Probing embryonic tissue mechanics with laser hole drilling. Physical Biology 6: 036004.
12. Gorfinkiel N, Blanchard GB, Adams RJ, Martinez Arias A, (2009) Mechanical control of global cell behaviour during dorsal closure in Drosophila. Development 136: 1889-1898.
13. Martin AC, Kaschube M, Wieschaus EF, (2009) Pulsed contractions of an actin-myosin network drive apical constriction. Nature 457: 495-499.
14. David DJ, Tishkina A, Harris TJ, (2010) The PAR complex regulates pulsed actomyosin contractions during amnioserosa apical constriction in Drosophila. Development 137: 1645-1655.
15. Homem CC, Peifer M, (2008) Diaphanous regulates myosin and adherens junctions to control cell contractility and protrusive behavior during morphogenesis. Development 135: 1005-1018.
16. Blanchard GB, Murugesu S, Adams RJ, Martinez-Arias A, Gorfinkiel N, (2010) Cytoskeletal dynamics and supracellular organisation of cell shape fluctuations during dorsal closure. Development 137: 2743-2752.
17. Barrett K, Leptin M, Settleman J, (1997) The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation. Cell 91: 905-915.
18. Hacker U, Perrimon N, (1998) DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. Genes & Dev 12: 274-284.
19. Kölsch V, Seher T, Fernandez-Ballester GJ, Serrano L, Leptin M, (2007) Control of Drosophila gastrulation by apical localization of adherens junctions and RhoGEF2. Science 315: 384-386.
20. Padash Barmchi M, Rogers S, Hacker U, (2005) DRhoGEF2 regulates actin organization and contractility in the Drosophila blastoderm embryo. J Cell Biol 168: 575-585.
21. Fabry B, Maksym GN, Butler JP, Glogauer M, Navajas D, Fredberg JJ, (2001) Scaling the microrheology of living cells. Phys Rev Lett 87: 148102.
22. Simões S, Denholm B, Azevedo D, Sotillos S, Martin P, et al. (2006) Compartmentalisation of Rho regulators directs cell invagination during tissue morphogenesis. Development 133: 4257-4267.
23. Simões SdeM, Blankenship JT, Weitz O, Farrell DL, Tamada M, et al. (2010) Rho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongation. Dev Cell 19: 377-388.
24. Oda H, Tsukita S, (2001) Real-time imaging of cell-cell adherens junctions reveals that Drosophila mesoderm invagination begins with two phases of apical constriction of cells. J Cell Sci 114: 493-501.
25. Brand AH, Perrimon N, (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
26. Chou T, Perrimon N, (1996) The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144: 1673-1679.
27. Campos I, Geiger JA, Santos AC, Carlos V, Jacinto A, (2010) Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair. Genetics 184: 129-140.
28. Wood W, Jacinto A, (2005) Imaging cell movement during dorsal closure in Drosophila embryos. Methods Mol Biol 294: 203-210.