메뉴 건너뛰기




Volumn 23, Issue 10, 2011, Pages 893-897

New insight in the pathogenesis of functional gastrointestinal disorders: Association between genetics and colonic transit

Author keywords

C11orf30; CDH1; ORMDL3; PRDM1; TLR9

Indexed keywords

ARTICLE; AUTOPHAGY; CELIAC DISEASE; CLINICAL FEATURE; DIGESTIVE SYSTEM FUNCTION DISORDER; ENTERITIS; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME ANALYSIS; HUMAN; INNATE IMMUNITY; INTESTINE EPITHELIUM; PATHOGENESIS; PRIORITY JOURNAL; RISK FACTOR;

EID: 80052835291     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2011.01774.x     Document Type: Article
Times cited : (8)

References (29)
  • 1
    • 0033665517 scopus 로고    scopus 로고
    • Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome
    • Spiller RC, Jenkins D, Thornley JP et al. Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut 2000; 47: 804-11.
    • (2000) Gut , vol.47 , pp. 804-811
    • Spiller, R.C.1    Jenkins, D.2    Thornley, J.P.3
  • 2
    • 59749085184 scopus 로고    scopus 로고
    • Mucosal immune activation in irritable bowel syndrome: gender-dependence and association with digestive symptoms
    • Cremon C, Gargano L, Morselli-Labate AM et al. Mucosal immune activation in irritable bowel syndrome: gender-dependence and association with digestive symptoms. Am J Gastroenterol 2009; 104: 392-400.
    • (2009) Am J Gastroenterol , vol.104 , pp. 392-400
    • Cremon, C.1    Gargano, L.2    Morselli-Labate, A.M.3
  • 3
    • 10744225624 scopus 로고    scopus 로고
    • Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
    • Barbara G, Stanghellini V, De GR et al. Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroenterology 2004; 126: 693-702.
    • (2004) Gastroenterology , vol.126 , pp. 693-702
    • Barbara, G.1    Stanghellini, V.2    De, G.R.3
  • 5
    • 4444377666 scopus 로고    scopus 로고
    • PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways
    • Cenac N, Chin AC, Garcia-Villar R et al. PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways. J Physiol 2004; 558: 913-25.
    • (2004) J Physiol , vol.558 , pp. 913-925
    • Cenac, N.1    Chin, A.C.2    Garcia-Villar, R.3
  • 6
    • 42549168553 scopus 로고    scopus 로고
    • Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity
    • Gecse K, Roka R, Ferrier L et al. Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity. Gut 2008; 57: 591-9.
    • (2008) Gut , vol.57 , pp. 591-599
    • Gecse, K.1    Roka, R.2    Ferrier, L.3
  • 7
    • 77954758654 scopus 로고    scopus 로고
    • The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models
    • Nell S, Suerbaum S, Josenhans C. The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models. Nat Rev Microbiol 2010; 8: 564-77.
    • (2010) Nat Rev Microbiol , vol.8 , pp. 564-577
    • Nell, S.1    Suerbaum, S.2    Josenhans, C.3
  • 8
    • 77950243833 scopus 로고    scopus 로고
    • Multiple common variants for celiac disease influencing immune gene expression
    • Dubois PC, Trynka G, Franke L et al. Multiple common variants for celiac disease influencing immune gene expression. Nat Genet 2010; 42: 295-302.
    • (2010) Nat Genet , vol.42 , pp. 295-302
    • Dubois, P.C.1    Trynka, G.2    Franke, L.3
  • 9
    • 79851490741 scopus 로고    scopus 로고
    • A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohns' disease and celiac disease
    • Festen EA, Goyette P, Green T et al. A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohns' disease and celiac disease. PLoS Genet 2011; 7: e1001283.
    • (2011) PLoS Genet , vol.7
    • Festen, E.A.1    Goyette, P.2    Green, T.3
  • 10
    • 78649489009 scopus 로고    scopus 로고
    • Genome-wide meta-analysis increases to 71 the number of confirmed Crohns' disease susceptibility loci
    • Franke A, McGovern DP, Barrett JC et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohns' disease susceptibility loci. Nat Genet 2010; 42: 1118-25.
    • (2010) Nat Genet , vol.42 , pp. 1118-1125
    • Franke, A.1    McGovern, D.P.2    Barrett, J.C.3
  • 11
    • 48349136889 scopus 로고    scopus 로고
    • Genome-wide association defines more than 30 distinct susceptibility loci for Crohns' disease
    • Barrett JC, Hansoul S, Nicolae DL et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohns' disease. Nat Genet 2008; 40: 955-62.
    • (2008) Nat Genet , vol.40 , pp. 955-962
    • Barrett, J.C.1    Hansoul, S.2    Nicolae, D.L.3
  • 12
    • 79952195585 scopus 로고    scopus 로고
    • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
    • Anderson CA, Boucher G, Lees CW et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet 2011; 43: 246-52.
    • (2011) Nat Genet , vol.43 , pp. 246-252
    • Anderson, C.A.1    Boucher, G.2    Lees, C.W.3
  • 13
    • 41149135384 scopus 로고    scopus 로고
    • Associations with tight junction genes PARD3 and MAGI2 in Dutch patients point to a common barrier defect for coeliac disease and ulcerative colitis
    • Wapenaar MC, Monsuur AJ, van Bodegraven AA et al. Associations with tight junction genes PARD3 and MAGI2 in Dutch patients point to a common barrier defect for coeliac disease and ulcerative colitis. Gut 2008; 57: 463-7.
    • (2008) Gut , vol.57 , pp. 463-467
    • Wapenaar, M.C.1    Monsuur, A.J.2    van Bodegraven, A.A.3
  • 14
    • 49349096750 scopus 로고    scopus 로고
    • Genetics of irritable bowel syndrome
    • Saito YA, Talley NJ. Genetics of irritable bowel syndrome. Am J Gastroenterol 2008; 103: 2100-4.
    • (2008) Am J Gastroenterol , vol.103 , pp. 2100-2104
    • Saito, Y.A.1    Talley, N.J.2
  • 15
    • 4644293513 scopus 로고    scopus 로고
    • Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women
    • Yeo A, Boyd P, Lumsden S et al. Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women. Gut 2004; 53: 1452-8.
    • (2004) Gut , vol.53 , pp. 1452-1458
    • Yeo, A.1    Boyd, P.2    Lumsden, S.3
  • 16
    • 33750004557 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism and irritable bowel syndrome
    • Park JM, Choi MG, Park JA et al. Serotonin transporter gene polymorphism and irritable bowel syndrome. Neurogastroenterol Motil 2006; 18: 995-1000.
    • (2006) Neurogastroenterol Motil , vol.18 , pp. 995-1000
    • Park, J.M.1    Choi, M.G.2    Park, J.A.3
  • 17
    • 34250172717 scopus 로고    scopus 로고
    • A genetic association study of 5-HTT LPR and GNbeta3 C825T polymorphisms with irritable bowel syndrome
    • Saito YA, Locke GR III, Zimmerman JM et al. A genetic association study of 5-HTT LPR and GNbeta3 C825T polymorphisms with irritable bowel syndrome. Neurogastroenterol Motil 2007; 19: 465-70.
    • (2007) Neurogastroenterol Motil , vol.19 , pp. 465-470
    • Saito, Y.A.1    Locke III, G.R.2    Zimmerman, J.M.3
  • 18
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • Lesch KP, Bengel D, Heils A et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996; 274: 1527-31.
    • (1996) Science , vol.274 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3
  • 19
    • 80051670660 scopus 로고    scopus 로고
    • Association between a serotonin transporter promoter polymorphism (5HTTLPR) and personality disorder traits in a community sample
    • Blom RM, Samuels JF, Riddle MA et al. Association between a serotonin transporter promoter polymorphism (5HTTLPR) and personality disorder traits in a community sample. J Psychiatr Res 2011; 45: 1153-9.
    • (2011) J Psychiatr Res , vol.45 , pp. 1153-1159
    • Blom, R.M.1    Samuels, J.F.2    Riddle, M.A.3
  • 20
    • 34548706490 scopus 로고    scopus 로고
    • Relationship of SERT polymorphisms to depressive and anxiety symptoms in irritable bowel syndrome
    • Jarrett ME, Kohen R, Cain KC et al. Relationship of SERT polymorphisms to depressive and anxiety symptoms in irritable bowel syndrome. Biol Res Nurs 2007; 9: 161-9.
    • (2007) Biol Res Nurs , vol.9 , pp. 161-169
    • Jarrett, M.E.1    Kohen, R.2    Cain, K.C.3
  • 21
    • 3242738347 scopus 로고    scopus 로고
    • Association of the -1438G/A and 102 T/C polymorphism of the 5-Ht2A receptor gene with irritable bowel syndrome 5-Ht2A gene polymorphism in irritable bowel syndrome
    • Pata C, Erdal E, Yazc K, Camdeviren H, Ozkaya M, Ulu O. Association of the -1438G/A and 102 T/C polymorphism of the 5-Ht2A receptor gene with irritable bowel syndrome 5-Ht2A gene polymorphism in irritable bowel syndrome. J Clin Gastroenterol 2004; 38: 561-6.
    • (2004) J Clin Gastroenterol , vol.38 , pp. 561-566
    • Pata, C.1    Erdal, E.2    Yazc, K.3    Camdeviren, H.4    Ozkaya, M.5    Ulu, O.6
  • 22
    • 79551700097 scopus 로고    scopus 로고
    • Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome
    • Jun S, Kohen R, Cain KC, Jarrett ME, Heitkemper MM. Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome. Neurogastroenterol Motil 2011; 23: 233-9.
    • (2011) Neurogastroenterol Motil , vol.23 , pp. 233-239
    • Jun, S.1    Kohen, R.2    Cain, K.C.3    Jarrett, M.E.4    Heitkemper, M.M.5
  • 23
    • 80052862553 scopus 로고    scopus 로고
    • Association of TNFSF15 polymorphism with irritable bowel syndrome
    • Epub ahead of print].
    • Zucchelli M, Camilleri M, Nixon AA et al. Association of TNFSF15 polymorphism with irritable bowel syndrome. Gut 2011; [Epub ahead of print].
    • (2011) Gut
    • Zucchelli, M.1    Camilleri, M.2    Nixon, A.A.3
  • 24
    • 38649131433 scopus 로고    scopus 로고
    • Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome
    • Aerssens J, Camilleri M, Talloen W et al. Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome. Clin Gastroenterol Hepatol 2008; 6: 194-205.
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 194-205
    • Aerssens, J.1    Camilleri, M.2    Talloen, W.3
  • 25
    • 77949833947 scopus 로고    scopus 로고
    • Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis
    • Villani AC, Lemire M, Thabane M et al. Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis. Gastroenterology 2010; 138: 1502-13.
    • (2010) Gastroenterology , vol.138 , pp. 1502-1513
    • Villani, A.C.1    Lemire, M.2    Thabane, M.3
  • 26
    • 79957485205 scopus 로고    scopus 로고
    • The eczema risk variant on chromosome 11q13 (rs7927894) in the population-based ALSPAC cohort: a novel susceptibility factor for asthma and hay fever
    • Marenholz I, Bauerfeind A, Esparza-Gordillo J et al. The eczema risk variant on chromosome 11q13 (rs7927894) in the population-based ALSPAC cohort: a novel susceptibility factor for asthma and hay fever. Hum Mol Genet 2011; 20: 2443-9.
    • (2011) Hum Mol Genet , vol.20 , pp. 2443-2449
    • Marenholz, I.1    Bauerfeind, A.2    Esparza-Gordillo, J.3
  • 27
    • 78249242440 scopus 로고    scopus 로고
    • Evidence for significant overlap between common risk variants for Crohns' disease and ankylosing spondylitis
    • Laukens D, Georges M, Libioulle C et al. Evidence for significant overlap between common risk variants for Crohns' disease and ankylosing spondylitis. PLoS ONE 2010; 5: e13795.
    • (2010) PLoS ONE , vol.5
    • Laukens, D.1    Georges, M.2    Libioulle, C.3
  • 28
    • 38849188779 scopus 로고    scopus 로고
    • Post-infectious irritable bowel syndrome
    • Dupont AW. Post-infectious irritable bowel syndrome. Curr Gastroenterol Rep 2007; 9: 378-84.
    • (2007) Curr Gastroenterol Rep , vol.9 , pp. 378-384
    • Dupont, A.W.1
  • 29
    • 77950670562 scopus 로고    scopus 로고
    • Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome
    • Tana C, Umesaki Y, Imaoka A, Handa T, Kanazawa M, Fukudo S. Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome. Neurogastroenterol Motil 2010; 22: 512-5.
    • (2010) Neurogastroenterol Motil , vol.22 , pp. 512-515
    • Tana, C.1    Umesaki, Y.2    Imaoka, A.3    Handa, T.4    Kanazawa, M.5    Fukudo, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.