A dopamine receptor (DRD2) but not dopamine transporter (DAT1) gene polymorphism is associated with neurocognitive development of Mexican preschool children with lead exposure

Journal of Pediatrics

Volumn 159, Issue 4, 2011, Pages 638-643

  Kordas, Katarzyna ^a   Ettinger, Adrienne S ^b   Bellinger, David C ^b,c   Schnaas, Lourdes ^d   Téllez Rojo, Martha María ^e   Hernández Avila, Mauricio ^f   Hu, Howard ^g   Wright, Robert O ^b,h  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d INSTITUTO NACIONAL DE PERINATOLOGÍA   (Mexico)

^e INSTITUTO NACIONAL DE SALUD PÚBLICA   (Mexico)

^f Subsecretaría de Prevención y Promoción de la Salud ^*  (Mexico)

^g UNIVERSITY OF MICHIGAN   (United States)

^h CHANNING LABORATORY   (United States)

Author keywords

BLL; Blood lead concentration; DAT1; Dopamine receptor 2; Dopamine transporter; DRD2; GCI; General Cognitive Index; MDI; Mental Development Index; PDI; Psychomotor Development Index; Variable number tandem repeat; VNTR

Indexed keywords

DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; DOPAMINE TRANSPORTER 1; LEAD; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHILD; COGNITIVE DEVELOPMENT; DOPAMINE METABOLISM; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; INDUSTRIAL WASTE; LEAD BLOOD LEVEL; LEAD EXPOSURE; MAJOR CLINICAL STUDY; MEMORY; MENTAL DEVELOPMENT; MEXICO; PRESCHOOL CHILD; PRIORITY JOURNAL; PSYCHOMOTOR DEVELOPMENT; RATING SCALE; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; UMBILICAL CORD BLOOD; VARIABLE NUMBER OF TANDEM REPEAT;

CHILD DEVELOPMENT; CHILD, PRESCHOOL; COGNITION DISORDERS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; ENVIRONMENTAL EXPOSURE; FEMALE; FETAL BLOOD; FOLLOW-UP STUDIES; HUMANS; LEAD; MALE; MEXICO; NEUROPSYCHOLOGICAL TESTS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RECEPTORS, DOPAMINE D2;

EID: 80052812413     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2011.03.043     Document Type: Article

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