Changes in cyclic nucleotides, locomotory behavior, and body length produced by novel endogenous neuropeptides in the parasitic nematode Ascaris suum

Molecular and Biochemical Parasitology

Volumn 180, Issue 1, 2011, Pages 27-34

  Reinitz, Catharine A ^a   Pleva, Anthony E ^a,b   Stretton, Antony O W ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Gilson Inc   (United States)

Author keywords

Ascaris suum; CAMP; cGMP; Locomotory behavior; Neuropeptides; Parasite

Indexed keywords

AF1 PROTEIN; AF10 PROTEIN; AF11 PROTEIN; AF13 PROTEIN; AF15 PROTEIN; AF19 PROTEIN; AF2 PROTEIN; AF21 PROTEIN; AF22 PROTEIN; AF23 PROTEIN; AF25 PROTEIN; AF26 PROTEIN; AF27 PROTEIN; AF28 PROTEIN; AF29 PROTEIN; AF3 PROTEIN; AF30 PROTEIN; AF31 PROTEIN; AF32 PROTEIN; AF33 PROTEIN; AF36 PROTEIN; AF4 PROTEIN; AF41 PROTEIN; AF5 PROTEIN; CYCLIC AMP; CYCLIC GMP; NEUROPEPTIDE; PHENYLALANYLMETHIONYLARGINYLPHENYLALANINAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; ASCARIS SUUM; BODY HEIGHT; CONTROLLED STUDY; LOCOMOTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PSEUDOCOELOMATA; WAVEFORM;

ANIMALS; ASCARIASIS; ASCARIS SUUM; BODY SIZE; CYCLIC AMP; CYCLIC GMP; FEMALE; HELMINTH PROTEINS; LOCOMOTION; NEUROPEPTIDES; SWINE; SWINE DISEASES;

ASCARIS; ASCARIS SUUM;

EID: 80052781456     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2011.08.001     Document Type: Article

References (52)

1. F.L. Strand Neuropeptides: regulators of physiological processes 1999 MIT Press Cambridge, MA
2. C. Cowden, and A.O. Stretton AF2, an Ascaris neuropeptide: isolation, sequence, and bioactivity Peptides 14 3 1993 423 430 (Pubitemid 223043155)
3. C. Cowden, and A.O. Stretton Eight novel FMRFamide-like neuropeptides isolated from the nematode Ascaris suum Peptides 16 3 1995 491 500
4. C. Cowden, A.O. Stretton, and R.E. Davis AF1, a sequenced bioactive neuropeptide isolated from the nematode Ascaris suum Neuron 2 5 1989 1465 1473
5. C. Li, and K. Kim Neuropeptides 2008
6. J.L. Jarecki, K. Andersen, C.J. Konop, J.J. Knickelbine, M.M. Vestling, and A.O. Stretton Mapping neuropeptide expression by mass spectrometry in single dissected identified neurons from the dorsal ganglion of the nematode Ascaris suum ACS Chem Neurosci 1 7 2010 505 519
7. A.G. Maule, C. Shaw, and J.W. Bowman KSAYMRFamide: a novel FMRFamide-related heptapeptide from the free-living nematode, Panagrellus redivivus, which is myoactive in the parasitic nematode, Ascaris suum Biochem Biophys Res Commun 200 2 1994 973 980
8. A.G. Maule, T.G. Geary, and J.W. Bowman Inhibitory effects of nematode FMRFamide-related peptides (FaRPs) on muscle strips from Ascaris suum Invert Neurosci 1 3 1995 255 265
9. J.Y. Yew, R. Davis, S. Dikler, J. Nanda, B. Reinders, and A.O. Stretton Peptide products of the afp-6 gene of the nematode Ascaris suum have different biological actions J Comp Neurol 502 5 2007 872 882 (Pubitemid 46732502)
10. J.Y. Yew, S. Dikler, and A.O. Stretton De novo sequencing of novel neuropeptides directly from Ascaris suum tissue using matrix-assisted laser desorption/ionization time-of-flight/time-of-flight Rapid Commun Mass Spectrom 17 24 2003 2693 2698 (Pubitemid 38029308)
11. J.Y. Yew, K.K. Kutz, S. Dikler, L. Messinger, L. Li, and A.O. Stretton Mass spectrometric map of neuropeptide expression in Ascaris suum J Comp Neurol 488 4 2005 396 413 (Pubitemid 40934679)
12. C. Li, K. Kim, and L.S. Nelson FMRFamide-related neuropeptide gene family in Caenorhabditis elegans Brain Res 848 1-2 1999 26 34 (Pubitemid 30001651)
13. P. McVeigh, S. Alexander-Bowman, E. Veal, A. Mousley, N.J. Marks, and A.G. Maule Neuropeptide-like protein diversity in phylum Nematoda Int J Parasitol 38 13 2008 1493 1503
14. P. McVeigh, S. Leech, G.R. Mair, N.J. Marks, T.G. Geary, and A.G. Maule Analysis of FMRFamide-like peptide (FLP) diversity in phylum Nematoda Int J Parasitol 35 10 2005 1043 1060 (Pubitemid 41219713)
15. A.N. Nathoo, R.A. Moeller, B.A. Westlund, and A.C. Hart Identification of neuropeptide-like protein gene families in Caenorhabditiselegans and other species Proc Natl Acad Sci U S A 98 24 2001 14000 14005 (Pubitemid 33116013)
16. D.J. Brownlee, I. Fairweather, L. Holden-Dye, and R.J. Walker Nematode neuropeptides: localization, isolation and functions Parasitol Today 12 9 1996 343 351 (Pubitemid 26268455)
17. C. Cowden, P. Sithigorngul, P. Brackley, J. Guastella, and A.O. Stretton Localization and differential expression of FMRFamide-like immunoreactivity in the nematode Ascaris suum J Comp Neurol 333 3 1993 455 468 (Pubitemid 23187539)
18. K. Kim, and C. Li Expression and regulation of an FMRFamide-related neuropeptide gene family in Caenorhabditis elegans J Comp Neurol 475 4 2004 540 550 (Pubitemid 38859364)
19. P. Sithigorngul, C. Cowden, and A.O. Stretton Heterogeneity of cholecystokinin/gastrin-like immunoreactivity in the nervous system of the nematode Ascaris suum J Comp Neurol 370 4 1996 427 442 (Pubitemid 26230630)
20. P. Sithigorngul, A.O. Stretton, and C. Cowden Neuropeptide diversity in Ascaris: an immunocytochemical study J Comp Neurol 294 3 1990 362 376 (Pubitemid 20117253)
21. J. White, E. Southgate, N. Thomson, and S. Brenner The structure of the nervous system of the nematode C. elegans Philos Trans R Soc Lond B Biol Sci 314 1986 1 340
22. A. Stretton, J. Donmoyer, R. Davis, J. Meade, C. Cowden, and P. Sithigorngul Motor behavior and motor nervous system function in the nematode Ascaris suum J Parasitol 78 2 1992 206 214
23. R.E. Davis, and A.O. Stretton The motornervous system of Ascaris: electrophysiology and anatomy of the neurons and their control by neuromodulators Parasitology 113 Suppl. 1996 S97 S117
24. R.E. Davis, and A.O. Stretton Structure-activity relationships of 18 endogenous neuropeptides on the motor nervous system of the nematode Ascaris suum Peptides 22 1 2001 7 23 (Pubitemid 32146679)
25. R.A. Fellowes, A.G. Maule, and N.J. Marks Modulation of the motility of the vagina vera of Ascaris suum in vitro by FMRF amide-related peptides Parasitology 116 Pt 3 1998 277 287 (Pubitemid 28129380)
26. L. Holden-Dye, D.J. Brownlee, and R.J. Walker The effects of the peptide KPNFIRFamide (PF4) on the somatic muscle cells of the parasitic nematode Ascaris suum Br J Pharmacol 120 3 1997 379 386 (Pubitemid 27052834)
27. J. Purcell, A.P. Robertson, D.P. Thompson, and R.J. Martin PF4, a FMRFamide-related peptide, gates low-conductance Cl(-) channels in Ascaris suum Eur J Pharmacol 456 1-3 2002 11 17 (Pubitemid 35351731)
28. C.A. Reinitz, H.G. Herfel, L.A. Messinger, and A.O. Stretton Changes in locomotory behavior and cAMP produced in Ascaris suum by neuropeptides from Ascaris suum or Caenorhabditis elegans Mol Biochem Parasitol 111 1 2000 185 197
29. S. Verma, A.P. Robertson, and R.J. Martin The nematode neuropeptide, AF2 (KHEYLRF-NH2), increases voltage-activated calcium currents in Ascaris suum muscle Br J Pharmacol 151 6 2007 888 899 (Pubitemid 47075326)
30. J.R. Vanfleteren, Y. Van de Peer, and M.L. Blaxter Molecular genealogy of some nematode taxa as based on cytochrome c and globin amino acid sequences Mol Phylogenet Evol 3 2 1994 92 101
31. P. Sithigorngul, J.L. Jarecki, and Stretton S A.O.W A specific antibody to neuropeptide AF1 (KNEFIRFamide) recognizes a small subset of neurons in Ascaris suum: differences from Caenorhabditis elegans. J Comp Neurol 519 8 2011 1546 1561
32. J.C. Nanda, and A.O. Stretton In situ hybridization of neuropeptide-encoding transcripts afp-1, afp-3, and afp-4 in neurons of the nematode Ascaris suum J Comp Neurol 518 6 2010 896 910
33. J.W. Bowman, A.R. Friedman, and D.P. Thompson Structure-activity relationships of KNEFIRFamide (AF1), a nematode FMRFamide-related peptide, on Ascaris suum muscle Peptides 17 3 1996 381 387 (Pubitemid 26180211)
34. J.W. Bowman, A.R. Friedman, D.P. Thompson, A.G. Maule, S.J. Alexander-Bowman, and T.G. Geary Structure-activity relationships of an inhibitory nematode FMRFamide-related peptide, SDPNFLRFamide (PF1), on Ascaris suum muscle Int J Parasitol 32 14 2002 1765 1771 (Pubitemid 35447605)
35. D.J. Brownlee, and R.J. Walker Actions of nematode FMRFamide-related peptides on the pharyngeal muscle of the parasitic nematode, Ascaris suum Ann N Y Acad Sci 897 1999 228 238 (Pubitemid 30040335)
36. D.P. Thompson, J.P. Davis, and M.J. Larsen Effects of KHEYLRFamide and KNEFIRFamide on cyclic adenosine monophosphate levels in Ascaris suum somatic muscle Int J Parasitol 33 2 2003 199 208 (Pubitemid 36298990)
37. N.A. Croll Behavioural analysis of nematode movement Adv Parasitol 13 1975 71 122
38. N.A. Croll The behaviour of nematodes: their activity, senses and responses 1970 Edward Arnold London
39. C.A. Reinitz, and A.O. Stretton Behavioral and cellular effects of serotonin on locomotion and male mating posture in Ascaris suum (Nematoda) J Comp Physiol A 178 5 1996 655 667
40. A.S. Edison, L.A. Messinger, and A.O. Stretton afp-1: a gene encoding multiple transcripts of a new class of FMRFamide-like neuropeptides in the nematode Ascaris suum Peptides 18 7 1997 929 935 (Pubitemid 27489366)
41. J. Nanda Molecular biological analysis of neuropeptide transcripts from the nematode Ascaris suum 2004 University of Wisconsin-Madison Madison
42. J.L. Jarecki Identification and localization of neuropeptides in Ascaris suum by mass spectrometry 2010 University of Wisconsin-Madison Madison
43. A.T. Dossey, V. Reale, and H. Chatwin NMR analysis of Caenorhabditis elegans FLP-18 neuropeptides: implications for NPR-1 activation Biochemistry 45 24 2006 7586 7597 (Pubitemid 43898664)
44. J.K. Horton, R.C. Martin, and S. Kalinka Enzyme immunoassays for the estimation of adenosine 3′,5′ cyclic monophosphate and guanosine 3′,5′ cyclic monophosphate in biological fluids J Immunol Methods 155 1 1992 31 40
45. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 1976 248 254
46. A.G. Maule, J.W. Bowman, D.P. Thompson, N.J. Marks, A.R. Friedman, and T.G. Geary FMRFamide-related peptides (FaRPs) in nematodes: occurrence and neuromuscular physiology Parasitology 113 Suppl. 1996 S119 S135
47. C.J. Franks, L. Holden-Dye, R.G. Williams, F.Y. Pang, and R.J. Walker A nematode FMRFamide-like peptide, SDPNFLRFamide (PF1), relaxes the dorsal muscle strip preparation of Ascaris suum Parasitology 108 Pt 2 1994 229 236 (Pubitemid 24056832)
48. L. Holden-Dye, C.J. Franks, R.G. Williams, and R.J. Walker The effect of the nematode peptides SDPNFLRFamide (PF1) and SADPNFLRFamide (PF2) on synaptic transmission in the parasitic nematode Ascaris suum Parasitology 110 Pt 4 1995 449 455
49. C.O. Ortiz, J.F. Etchberger, and S.L. Posy Searching for neuronal left/right asymmetry: genomewide analysis of nematode receptor-type guanylyl cyclases Genetics 173 1 2006 131 149 (Pubitemid 43800189)
50. D. Fioravante, P.D. Smolen, and J.H. Byrne The 5-HT- and FMRFa-activated signaling pathways interact at the level of the Erk MAPK cascade: potential inhibitory constraints on memory formation Neurosci Lett 396 3 2006 235 240 (Pubitemid 43331038)
51. I.R. Viola Comparing the cellular localization of Ascaris neuropeptides using immunocytochemistry, molecular biology and mass spectrometry 2011 University of Wisconsin-Madison Madison
52. K.M. Andersen Development of single neuron mass spectrometry in Ascaris suum 2010 University of Wisconsin-Madison Madison