The significance of PITX2 overexpression in human colorectal cancer

Annals of Surgical Oncology

Volumn 18, Issue 10, 2011, Pages 3005-3012

  Hirose, Hajime ^a   Ishii, Hideshi ^a,b   Mimori, Koshi ^b   Tanaka, Fumiaki ^b   Takemasa, Ichiro ^a   Mizushima, Tsunekazu ^a   Ikeda, Masataka ^a   Yamamoto, Hirofumi ^a   Sekimoto, Mitsugu ^a   Doki, Yuichiro ^a   Mori, Masaki ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR PITX2;

AGED; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CANCER LOCALIZATION; CANCER SIZE; CANCER STAGING; CANCER SURVIVAL; CANCER TISSUE; CELL GROWTH; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER METASTASIS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE;

ADENOCARCINOMA; AGED; CELL PROLIFERATION; COLON; COLORECTAL NEOPLASMS; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOENZYME TECHNIQUES; LIVER NEOPLASMS; LYMPHATIC METASTASIS; MALE; NEOPLASM STAGING; PERITONEAL NEOPLASMS; PROGNOSIS; RECTUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SURVIVAL RATE; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 80052738633     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-011-1653-z     Document Type: Article

References (35)

1. SI Kohno C Luo A Nawa, et al. 2007 Oncolytic virotherapy with an HSV amplicon vector expressing granulocyte-macrophage colony-stimulating factor using the replication-competent HSV type 1 mutant HF10 as a helper virus Cancer Gene Ther 14 11 918 926 17693992 10.1038/sj.cgt.7701070 1:CAS:528: DC%2BD2sXhtFChur%2FP (Pubitemid 47558955)
2. M Hermsen C Postma J Baak, et al. 2002 Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability Gastroenterology 123 4 1109 1119 12360473 10.1053/gast.2002.36051 1:CAS:528:DC%2BD38Xotl2gu70%3D
3. A Leslie NR Pratt K Gillespie, et al. 2003 Mutations of APC, K-ras, and p53 are associated with specific chromosomal aberrations in colorectal adenocarcinomas Cancer Res 63 15 4656 4661 12907646 1:CAS:528: DC%2BD3sXmtFersbw%3D (Pubitemid 36951044)
4. XY Xiao XY Zhou G Yan, et al. 2007 Chromosomal alteration in Chinese sporadic colorectal carcinomas detected by comparative genomic hybridization Diagn Mol Pathol 16 2 96 103 17525679 10.1097/PDM.0b013e31803190f2 1:CAS:528:DC%2BD2sXmvFGrtr4%3D (Pubitemid 47164742)
5. P Li S Maines-Bandiera WL Kuo, et al. 2007 Multiple roles of the candidate oncogene ZNF217 in ovarian epithelial neoplastic progression Int J Cancer 120 9 1863 1873 17266044 10.1002/ijc.22300 1:CAS:528:DC%2BD2sXjsVCqs7Y%3D (Pubitemid 46418361)
6. SH Cheng MH Ng KM Lau, et al. 2007 4q loss is potentially an important genetic event in MM tumorigenesis: identification of a tumor suppressor gene regulated by promoter methylation at 4q13.3, platelet factor, 4 Blood. 109 5 2089 2099 17077331 10.1182/blood-2006-04-018770 1:CAS:528:DC%2BD2sXjtFequrg%3D (Pubitemid 46348210)
7. KY Chan PB Lai JA Squire, et al. 2006 Positional expression profiling indicates candidate genes in deletion hotspots of hepatocellular carcinoma Mod Pathol 19 12 1546 1554 16980951 10.1038/modpathol.3800674 1:CAS:528: DC%2BD28Xht1akur%2FO (Pubitemid 44789922)
8. JU Kang JJ Kang KC Kwon, et al. 2006 Genetic alterations in primary gastric carcinomas correlated with clinicopathological variables by array comparative genomic hybridization J Korean Med Sci 21 4 656 665 16891809 10.3346/jkms.2006.21.4.656 1:CAS:528:DC%2BD28XpvVClsL0%3D
9. A Sterian T Kan AT Berki, et al. 2006 Mutational and LOH analyses of the chromosome 4q region in esophageal adenocarcinoma Oncology 70 3 168 172 16837775 10.1159/000094444 1:CAS:528:DC%2BD28XnsFCktLc%3D (Pubitemid 44154689)
10. Y Midorikawa S Yamamoto S Ishikawa, et al. 2006 Molecular karyotyping of human hepatocellular carcinoma using single-nucleotide polymorphism arrays Oncogene 25 40 5581 5590 16785998 10.1038/sj.onc.1209537 1:CAS:528: DC%2BD28XptFCmuro%3D (Pubitemid 44344109)
11. KJ Dykema KA Furge 2004 Diminished transcription of chromosome arm 4q is inversely related to local spreading of hepatocellular carcinoma Genes Chromosomes Cancer 41 4 390 394 15390189 10.1002/gcc.20090 1:CAS:528: DC%2BD2cXhtVOqtrzE (Pubitemid 39488497)
12. S Franke I Wlodarska B Maes, et al. 2001 Lymphocyte predominance Hodgkin disease is characterized by recurrent genomic imbalances Blood 97 6 1845 1853 11238128 10.1182/blood.V97.6.1845 1:CAS:528:DC%2BD3MXitFalur0%3D (Pubitemid 32217253)
13. A Pimkhaokham Y Shimada Y Fukuda, et al. 2000 Nonrandom chromosomal imbalances in esophageal squamous cell carcinoma cell lines: possible involvement of the ATF3 and CENPF genes in the 1q32 amplicon Jpn J Cancer Res 91 11 1126 1133 11092977 1:CAS:528:DC%2BD3cXosVGrsL0%3D
14. Y Fujimoto Y Kohgo 1998 Alteration of genomic structure and/or expression of cancer associated genes in hepatocellular carcinoma Rinsho Byori 46 1 9 14 9492532
15. M Tirkkonen O Johannsson BA Agnarsson, et al. 1997 Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations Cancer Res 57 7 1222 1227 9102202 1:CAS:528: DyaK2sXit1Kqu7o%3D (Pubitemid 27152540)
16. MH Quentien F Pitoia G Gunz, et al. 2002 Regulation of prolactin, GH, and Pit-1 gene expression in anterior pituitary by Pitx2: An approach using Pitx2 mutants Endocrinology 143 8 2839 2851 12130547 10.1210/en.143.8.2839 1:CAS:528:DC%2BD38Xls1Sgsbk%3D (Pubitemid 34809854)
17. M Logan SM Pagan-Westphal DM Smith, et al. 1998 The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals Cell 94 3 307 317 9708733 10.1016/S0092-8674(00)81474-9 1:CAS:528:DyaK1cXlsVWjs7w%3D (Pubitemid 28376075)
18. AK Ryan B Blumberg C Rodriguez-Esteban, et al. 1998 Pitx2 determines left-right asymmetry of internal organs in vertebrates Nature 394 6693 545 551 9707115 10.1038/29004 1:CAS:528:DyaK1cXltlyitrc%3D (Pubitemid 28366821)
19. SH Baek C Kioussi P Briata, et al. 2003 Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway Proc Natl Acad Sci USA 100 6 3245 3250 12629224 10.1073/pnas.0330217100 1:CAS:528:DC%2BD3sXisVCnt7w%3D (Pubitemid 36356568)
20. C Kioussi P Briata SH Baek, et al. 2002 Identification of a Wnt/Dvl/beta-Catenin → Pitx2 pathway mediating cell-type-specific proliferation during development Cell 111 5 673 685 12464179 10.1016/S0092-8674(02)01084-X 1:CAS:528:DC%2BD38XptlGrtbY%3D (Pubitemid 35441249)
21. S Maier I Nimmrich T Koenig, et al. 2007 DNA-methylation of the homeodomain transcription factor PITX2 reliably predicts risk of distant disease recurrence in tamoxifen-treated, node-negative breast cancer patients-Technical and clinical validation in a multi-centre setting in collaboration with the European Organisation for Research and Treatment of Cancer (EORTC) PathoBiology group Eur J Cancer 43 11 1679 1686 17601725 10.1016/j.ejca.2007.04.025 1:CAS:528:DC%2BD2sXnslWjtLs%3D (Pubitemid 47042374)
22. T Hampton 2006 New markers may help predict prostate cancer relapse risk JAMA 295 19 2234 2238 16705097 10.1001/jama.295.19.2234 1:CAS:528: DC%2BD28Xkslyku7Y%3D (Pubitemid 43736562)
23. H Hoshino N Miyoshi K Nagai, et al. 2009 Epithelial-mesenchymal transition with expression of SNAI1-induced chemoresistance in colorectal cancer Biochem Biophys Res Commun 390 3 1061 1065 19861116 10.1016/j.bbrc.2009.10.117 1:CAS:528:DC%2BD1MXhsVKgt7fO
24. Sobin LH, Fleming ID, TNM classification of malignant tumors, fifth edition. Union Internationale Contre le Cancer and the American Joint Committee on Cancer. Cancer. 1997;80(9):1803-4.
25. N Miyoshi H Ishii M Sekimoto, et al. 2009 RGS16 is a marker for prognosis in colorectal cancer Ann Surg Oncol 16 12 3507 3514 19760045 10.1245/s10434-009-0690-3
26. K Mimori M Mori T Shiraishi, et al. 1997 Clinical significance of tissue inhibitor of metalloproteinase expression in gastric carcinoma Br J Cancer 76 4 531 536 9275032 10.1038/bjc.1997.420 1:CAS:528:DyaK2sXlvV2nsLc%3D (Pubitemid 27331220)
27. M Mori RJ Staniunas GF Barnard, et al. 1993 The significance of carbonic anhydrase expression in human colorectal cancer Gastroenterology 105 3 820 826 8359652 1:STN:280:DyaK3szms1Whuw%3D%3D (Pubitemid 23249492)
28. H Yamamoto M Kondo S Nakamori, et al. 2003 JTE-522, a cyclooxygenase-2 inhibitor, is an effective chemopreventive agent against rat experimental liver fibrosis1 Gastroenterology 125 2 556 571 12891558 10.1016/S0016-5085(03)00904-1 1:CAS:528:DC%2BD3sXmvFynsrs%3D (Pubitemid 36929437)
29. EV Semina R Reiter NJ Leysens, et al. 1996 Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome Nat Genet 14 4 392 399 8944018 10.1038/ng1296-392 1:CAS:528:DyaK28XntlGhsL8%3D (Pubitemid 26414582)
30. CS Moreno CO Evans X Zhan, et al. 2005 Novel molecular signaling and classification of human clinically nonfunctional pituitary adenomas identified by gene expression profiling and proteomic analyses Cancer Res 65 22 10214 10222 16288009 10.1158/0008-5472.CAN-05-0884 1:CAS:528:DC%2BD2MXht1WgurbJ (Pubitemid 41743713)
31. ML Muccielli S Martinez A Pattyn, et al. 1996 Otlx2, an Otx-related homeobox gene expressed in the pituitary gland and in a restricted pattern in the forebrain Mol Cell Neurosci 8 4 258 271 9026314 10.1006/mcne.1996.0062 1:STN:280:DyaK2s7nslSrsQ%3D%3D (Pubitemid 27057150)
32. I Pellegrini-Bouiller C Manrique G Gunz, et al. 1999 Expression of the members of the Ptx family of transcription factors in human pituitary adenomas J Clin Endocrinol Metab 84 6 2212 2220 10372733 10.1210/jc.84.6.2212 1:CAS:528:DyaK1MXjs1Ohtrw%3D (Pubitemid 30647056)
33. M Bacac E Migliavacca JC Stehle, et al. 2006 A gene expression signature that distinguishes desmoid tumours from nodular fasciitis J Pathol 208 4 543 553 16440290 10.1002/path.1915 1:CAS:528:DC%2BD28XislCqt7k%3D (Pubitemid 43329341)
34. B Zirn B Samans S Wittmann, et al. 2006 Target genes of the WNT/beta-catenin pathway in Wilms tumors Genes Chromosomes Cancer 45 6 565 574 16575872 10.1002/gcc.20319 1:CAS:528:DC%2BD28XktlCruro%3D (Pubitemid 43727163)
35. H Arakawa T Nakamura AB Zhadanov, et al. 1998 Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene Proc Natl Acad Sci USA 95 8 4573 4578 9539779 10.1073/pnas.95.8.4573 1:CAS:528:DyaK1cXis1OgsL0%3D (Pubitemid 28207954)