Anti-inflammatory potential of ethanolic leaf extract of eupatorium adenophorum spreng. Through alteration in production of TNF-α, ROS and expression of certain genes

Evidence-based Complementary and Alternative Medicine

Volumn 2011, Issue , 2011, Pages

  Chakravarty, Ashim K ^a   Mazumder, Tamal ^a   Chatterjee, Shankar N ^b  

^a UNIVERSITY OF NORTH BENGAL   (India)

^b Ministry of Textiles   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; ALCOHOL; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; EUPATORIUM ADENOPHORUM EXTRACT; HERBACEOUS AGENT; HYDROXYL RADICAL; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; PERFORIN; PLANT EXTRACT; PROSTAGLANDIN; PROTEIN KINASE C ETA; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DOWN REGULATION; DRUG EFFICACY; EUPATORIUM ADENOPHORUM; FEMALE; FOOT; GENE EXPRESSION; INFLAMMATION; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT LEAF; PRIORITY JOURNAL; PROSTAGLANDIN METABOLISM; PROTEIN BLOOD LEVEL; SPLEEN; TISSUE REPAIR;

EID: 80052738148     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/neq033     Document Type: Article

References (73)

1. Simmons D. L., What makes a good anti-inflammatory drug target? Drug Discovery Today 2006 11 5-6 210 219
2. Saukkonen K., Sande S., Cioffe C., Wolpe S., Sherry B., Cerami A., Tuomanen E., The role of cytokines in the generation of inflammation and tissue damage in experimental gram-positive meningitis Journal of Experimental Medicine 1990 171 2 439 448 (Pubitemid 20059038)
3. Parenteau N. L., Hardin-Young J., The biological mechanisms behind injury and inflammation: how they can affect treatment strategy, product performance, and healing Wounds 2007 19 4 87 96
4. Fabbri L. M., Saetta M., Picotti G., Mapp C. E., Late asthmatic reactions, airway inflammation and chronic asthma in toluene-diisocyanate- sensitized subjects Respiration 1991 58 1 18 21
5. Stevens R. J., Douglas K. M. J., Saratzis A. N., Kitas G. D., Inflammation and atherosclerosis in rheumatoid arthritis Expert Reviews in Molecular Medicine 2005 7 7 1 24
6. Klareskog L., Padyukov L., Rnnelid J., Alfredsson L., Genes, environment and immunity in the development of rheumatoid arthritis Current Opinion in Immunology 2006 18 6 650 655 (Pubitemid 44635174)
7. Simka M., Blood brain barrier compromise with endothelial inflammation may lead to autoimmune loss of myelin during multiple sclerosis Current Neurovascular Research 2009 6 2 132 139
8. Zipser R. D., Mediators of inflammation in inflammatory bowel disease Digestive Diseases and Sciences 1988 33 3 4S 5S
9. Drews J., Ryser S., Classic drug targets Nature Biotechnology 1997 15 1318 1319
10. Kong D.-X., Li X.-J., Zhang H.-Y., Where is the hope for drug discovery? Let history tell the future Drug Discovery Today 2009 14 3-4 115 119
11. AuLD B. A., Martins P. M., The autecology of Eupatorium adenophorum Spreng. In Austraha Weed Research 1975 15 27 31
12. Muschietti L., Derita M., Slsen V., Muoz J. D. D., Ferraro G., Zacchino S., Martino V., In vitro antifungal assay of traditional Argentine medicinal plants Journal of Ethnopharmacology 2005 102 2 233 238 (Pubitemid 41483564)
13. Ahmed E., Arshad M., Ahmad M., Saeed M., Ishaque M., Ethnopharmacological survey of some medicinally important plkants of Galliyat areas of NWFP, Pakistan Asian Journal of Plant Sciences 2004 3 410 415
14. Castillo-Espaa P., Cisneros-Estrada A., Garduo-Ramrez M. L., Hernndez-Abreu O., Ramrez R., Estrada-Soto S., Preliminary ethnopharmacological survey of plants used in Mexico for the treatment of hypertension Pharmacognosy Reviews 2009 3 41 65
15. Pieroni A., Giusti M. E., de Pasquale C., Circum-Mediterranean cultural heritage and medicinal plant uses in traditional animal healthcare: a field survey in eight selected areas within the RUBIA project Journal of Ethnobiology and Ethnomedicine 2006 2 16 27
16. Heinrich M., Robles M., West J. E., Ortiz De Montellano B. R., Rodriguez E., Ethnopharmacology of Mexican asteraceae (compositae) Annual Review of Pharmacology and Toxicology 1998 38 539 565 (Pubitemid 28231505)
17. Monks N. R., Ferraz A., Bradgnon S. A., Machado K. R., Richter M. F., DaRocha A. B., In vitro cytotoxicity of extracts from Brazilian Asteraceae Pharmaceutical Biology 2002 40 494 500 (Pubitemid 36801713)
18. Akkol E. K., Koca U., Pesin I., Yilmazer D., Evaluation of the wound healing potential of Achillea biebersteinii Afan. (Asteraceae) by in vivo excision and incision models. Evidence-Based Complementary and Alternative Medicine. In press
19. Uddin S. J., Grice I. D., Tiralongo E., Cytotoxic effects of Bangladeshi plant extracts. Evidence-Based Complementary and Alternative Medicine. In press
20. Mandal S. K., Boominathan R., Parimaladevi B., Dewanjee S., Mandal S. C., Analgesic activity of methanol extract of Eupatorium adenophorum Spreng. leaves Indian Journal of Experimental Biology 2005 43 7 662 663 (Pubitemid 40962678)
21. Matsushima G. K., Stohlman S. A., Maturation of the delayed-type hypersensitivity response in SJL mice: absence of effector cell induction European Journal of Immunology 1988 18 9 1411 1416
22. Bandyopadhyay U., Das D., Banerjee R. K., Reactive oxygen species: oxidative damage and pathogenesis Current Science 1999 77 5 658 666 (Pubitemid 129558409)
23. Dedon P. C., Tannenbaum S. R., Reactive nitrogen species in the chemical biology of inflammation Archives of Biochemistry and Biophysics 2004 423 1 12 22 (Pubitemid 38202218)
24. Halliwell B., Hoult J. R., Blake D. R., Oxidants, inflammation, and anti-inflammatory drugs FASEB Journal 1988 2 13 2867 2873
25. Barnes P. J., Reactive oxygen species and airway inflammation Free Radical Biology and Medicine 1990 9 3 235 243
26. Nguemfol E. L., Dimol T., Dongmo A. B., Anti-oxidative and anti-inflammatory activities of some isolated constituents from the stem bark of Allanblackia monticola Staner L.C (Guttiferae) Inflammopharmacology 2009 17 37 41
27. Abreu P., Matthew S., Gonzlez T., Costa D., Segundo M. A., Fernandes E., Anti-inflammatory and antioxidant activity of a medicinal tincture from Pedilanthus tithymaloides Life Sciences 2006 78 14 1578 1585 (Pubitemid 43259465)
28. Joseph S., Sabulal B., George V., Smina T. P., Janardhanan K. K., Antioxidative and antiinflammatory activities of the chloroform extract of Ganoderma lucidum found in South India Scientia Pharmaceutica 2009 77 1 111 121
29. Dinarello C. A., Proinflammatory cytokines Chest 2000 118 503 508 (Pubitemid 30637822)
30. Strieter R., Kunkel S., Bone R., Role of tumor necrosis factor-alpha in disease states and inflammation Critical Care Medicine 1993 21 S447 S463
31. Lukacs N. W., Strieter R. M., Chensue S. W., Widmer M., Kunkel S. L., TNF- mediates recruitment of neutrophils and eosinophils during airway inflammation Journal of Immunology 1995 154 10 5411 5417
32. Tracey K. J., Cerami A., Tumor necrosis factor: a pleiotropic cytokine and therapeutic target Annual Review of Medicine 1994 45 491 503
33. Schweizer A., Feige U., Fontana A., Muller K., Dinarello C. A., Interleukin-1 enhances pain reflexes: mediation through increased prostaglandin E2 levels Agents Actions 1998 25 246 251
34. Gabay C., Interleukin-6 and chronic inflammation Arthritis Research Therapy 2006 8 supplement 2 S3 S8
35. Omoigui S., The interleukin-6 inflammation pathway from cholesterol to agingrole of statins, bisphosphonates and plant polyphenols in aging and age-related diseases Immunity and Ageing 2007 4 1 22
36. Jutel M., Akdis M., Budak F., Aebischer-Casaulta C., Wrzyszcz M., Blaser K., Akdis C. A., IL-10 and TGF- cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy European Journal of Immunology 2003 33 5 1205 1214 (Pubitemid 36609138)
37. Alkalay I., Yaron A., Hatzubai A., Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway Proceedings of the National Academy of Sciences of the United States of America 1995 92 10599 10603 (Pubitemid 3009135)
38. Pande V., Ramos M. J., NF- B in human disease: current inhibitors and prospects for de novo structure based design of inhibitors Current Medicinal Chemistry 2005 12 3 357 374 (Pubitemid 40305625)
39. Tak P. P., Firestein G. S., NF-kappaB: a key role in inflammatory diseases Journal of Clinical Investigation 2001 107 7 11 (Pubitemid 32047405)
40. Yamamoto Y., Gaynor R. B., Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer Journal of Clinical Investigation 2001 107 135 142 (Pubitemid 32096826)
41. Turini M. E., DuBois R. N., Cyclooxygenase-2: a therapeutic target Annual Review of Medicine 2002 53 35 57 (Pubitemid 34177870)
42. Smith C. J., Zhang Y., Koboldt C. M., Pharmacological analysis of cycloxygenase 1 in inflammation Proceedings of the National Academy of Sciences of the United States of America 1998 95 13313 13318
43. Smith W. L., Garavito R. M., DeWitt D. L., Prostaglandin endoperoxide H synthase (cyclooxygenases)-1 and -2 The Journal of Biological Chemistry 1996 271 33157 33160
44. Mitchell J. A., Larkin S., Williams T. J., Cyclooxygenase 2: regulation and relevance in inflammation Biochemical Pharmacology 1995 50 1535 1542
45. Vane J. R., Bakhle Y. S., Botting R. M., Cyclooxygenases 1 and 2 Annual Review of Pharmacology and Toxicology 1998 38 97 120 (Pubitemid 28231490)
46. Chen F., Sun S., Kuhn D. C., Gaydos L. J., Shi X., Lu Y., Demers L. M., Involvement of NF- B in silica-induced cyclooxygenase II gene expression in rat alveolar macrophages American Journal of Physiology 1997 272 4 L779 L786
47. Devaux Y., Seguin C., Grosjean S., Lipopolysaccharide-induced increase of prostaglandin E(2) is mediated by inducible nitric oxide synthase activation of the constitutive cyclooxygenase and induction of membrane-associated prostaglandin E synthase Journal of Immunology 2001 167 3962 3971 (Pubitemid 32910842)
48. Chakravarty A. K., Chatterjee S. N., Yasmin H., Mazumder T., Comparison of efficacy of turmeric and commercial curcumin in immunological functions and gene regulation International Journal of Pharmacology 2009 5 333 345
49. Chakravarty A. K., Yasmin H., Activation of cell mediated immune response and apoptosis towards malignant cells with turmeric treatment in murine model Indian Journal of Biochemistry and Biophysics 2008 45 1 23 29 (Pubitemid 351852121)
50. Chakravarty A. K., Yasmin H., Alcoholic turmeric extract simultaneously activating murine lymphocytes and inducing apoptosis of Ehlrich ascitic carcinoma cells International Immunopharmacology 2005 5 10 1574 1581 (Pubitemid 40967915)
51. Chakravarty A. K., Yasmin H., Das S. K., Two way efficacy of alcoholic turmeric extract: stimulatory for murine lymphocytes and inhibitory for ascetic fibrosarcoma Pharmaceutical Biology 2004 42 217 224 (Pubitemid 39611764)
52. Iijima M., Katz S. I., Specific immunologic tolerance to dinitrofluorobenzene following topical application of dinitrothiocyanobenzene: modulation by suppressor T cells Journal of Investigative Dermatology 1983 81 4 325 330 (Pubitemid 13013576)
53. Chakravarty A. K., Maitra U. K., Polyclonally stimulated murine T cells in control fibrosarcoma in situ Journal of the Indian Institute of Science 1990 70 503 516
54. Busch R., Cesar D., Higuera-Alhino D., Gee T., Hellerstein M. K., McCune J. M., Isolation of peripheral blood CD4 + T cells using RosetteSepTM and MACSTM for studies of DNA turnover by deuterium labeling Journal of Immunological Methods 2004 286 97 109 (Pubitemid 38490400)
55. Matheu M. P., Cahalan M. D., Isolation of CD4+ T cells from mouse lymph nodes using Miltenyi MACS purification Journal of Visualized Experiments 2007 9 409
56. Stanciu L. A., Djukanovi R., Isolation of T-cell subsets by magnetic cell sorting (MACS) Methods in Molecular Biology 2000 134 133 141
57. Sureshkumar V., Paul B., Uthirappan M., Pro-inflammatory and anti-inflammatory cytokine balance in gasoline exhaust induced pulmonary injury in mice Inhalation Toxicology 2005 17 161 168 (Pubitemid 40283868)
58. Sirish Kumar I. V. M. L. R., Paul B. N., Asthama R., Saxena A. K., Mehrotra S., Rajan G., Swertia Chirayita mediated modulation of interleukin-1, interleukin-6, interleukin-10, interferon- and tumor necrosis factor- in arthritic mice Immunopharmacology and Immunotoxicology 2003 25 573 583 (Pubitemid 37517857)
59. Drew P. D., Chavis J. A., Female sex steroids: effects upon microglial cell activation Journal of Neuroimmunology 2000 111 1-2 77 85
60. Halliwell B., Gutteridge J. M. C., Aruoma O. I., The deoxyribose method: a simple test-tube assay for determination of rate constants for reactions of hydroxyl radicals Analytical Biochemistry 1987 165 1 215 219 (Pubitemid 17131019)
61. Rappolee D. A., Mark D., Banda M. J., Werb Z., Wound macrophages express TGF- and other growth factors in vivo: analysis by mRNA phenotyping Science 1988 241 708 712
62. Rappolee D. A., Brenner C. A., Schultz R., Mark D., Werb Z., Developmental expression of PDGF, TGF-, and TGF- genes in preimplantation mouse embryos Science 1988 241 4874 1823 1825
63. Ehlers S., Mielke M. E. A., Hahn H., CD4+ T cell associated cytokine gene expression during experimental infection with Listeria monocytogenes: the mRNA phenotype of granuloma formation International Immunology 1994 6 11 1727 1737 (Pubitemid 24357885)
64. Poulter L. W., Seymour G. J., Duke O., Janossy G., Panayi G., Immunohistological analysis of delayed-type hypersensitivity in man Cell Immunology 1982 74 358 369 (Pubitemid 13147284)
65. Banno T., Gazel A., Blumenberg M., Effects of tumor necrosis factor- (TNF ) in epidermal keratinocytes revealed using global transcriptional profiling Journal of Biological Chemistry 2004 279 31 32633 32642 (Pubitemid 39014721)
66. Yoshida S., Ono M., Shono T., Izumi H., Ishibashi T., Suzuki H., Kuwano M., Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis Molecular and Cellular Biology 1997 17 7 4015 4023 (Pubitemid 27281877)
67. Berg J., Fellier H., Christoph T., Grarup J., Stimmeder D., The analgesic NSAID lornoxicam inhibits cyclooxygenase (COX)-1/-2, inducible nitric oxide synthase (iNOS), and the formation of interleukin (IL)-6 in vitro Inflammation Research 1999 48 7 369 385
68. Kohli K., Ali J., Ansari M. J., Raheman Z., Curcumin: a natural antiinflammatory agent Indian Journal of Pharmacology 2005 37 3 141 147 (Pubitemid 40898222)
69. Barcellos-Hoff M. H., Radiation-induced transforming growth factor and subsequent extracellular matrix reorganization in murine mammary gland Cancer Research 1993 53 17 3880 3886 (Pubitemid 23267682)
70. Chao C. C., Hu S., Sheng W. S., Tsang M., Peterson P. K., Tumor necrosis factor- mediates the release of bioactive transforming growth factor- in murine microglial cell cultures Clinical Immunology and Immunopathology 1995 77 358 365
71. Sullivan D. E., Ferris M., Pociask D., Brody A. R., Tumor necrosis factor- induces transforming growth factor- 1 expression in lung fibroblasts through the extracellular signal-regulated kinase pathway American Journal of Respiratory Cell and Molecular Biology 2005 32 342 349 (Pubitemid 40478310)
72. Salvioli S., Sikora E., Cooper E. L., Franceschi C., Curcumin in cell death processes: a challenge for CAM of age-related pathologies Evidence-Based Complementary and Alternative Medicine 2007 4 2 181 190
73. Zhang M.-L., Wu M., Zhang J.-J., Irwin D., Gu Y.-C., Shi Q.-W., Chemical constituents of plants from the genus Eupatorium Chemistry and Biodiversity 2008 5 1 40 55 (Pubitemid 351200995)