Pharmaconutrition: How has this concept evolved in the last two decades?

Nutrition

Volumn 27, Issue 10, 2011, Pages 1090-1092

  Hardy, Gil ^a   Manzanares, William ^b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CYSTEINE; GLUTAMINE; GLUTATHIONE; HEAT SHOCK PROTEIN; NITROGEN; NUCLEOTIDE; NUTRACEUTICAL; OMEGA 3 FATTY ACID; SELENIUM;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; DIET THERAPY; DRUG POTENTIATION; ENTERIC FEEDING; FUNCTIONAL FOOD; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; INFECTION PREVENTION; MEDICAL RESEARCH; NONHUMAN; NUTRITIONAL SUPPORT; PRIORITY JOURNAL; PROTEIN INDUCTION; STRESS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TISSUE METABOLISM;

AMINO ACIDS; DIET THERAPY; DIETARY SUPPLEMENTS; FATTY ACIDS, OMEGA-3; HUMANS; NUCLEOTIDES; NUTRITIONAL SUPPORT;

EID: 80052712627     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2011.01.009     Document Type: Article

References (23)

1. Newsholme E.A., Hardy G. Supplementation of diets with nutritional pharmaceuticals. Nutrition 1997, 13:837-839.
2. Hardy G. Nutraceuticals and functional foods. Nutrition 2000, 16:688-689.
3. Furst P., Kuhn K.S. Amino-acids substrates in new bottles: implications for clinical nutrition in the 21st century. Nutrition 2000, 16:603-606.
4. Jones N.E., Heyland D.K. Pharmaconutrition: a new emerging paradigm. Curr Opin Gastroenterol 2008, 24:215-222.
5. Waitzberg D.L., Saito H., Plank L.D., Jamieson G.G., Jagannath P., Hwang T.L., et al. Postsurgical infections are reduced with specialized nutrition support. World J Surg 2006, 30:1592-1604.
6. Yarandi S.S., Zhao V.M., Hebbar G., Ziegler T.R. Amino acid composition in parenteral nutrition: what is the evidence?. Curr Opin Clin Nutr Metab Care 2011, 14:75-82.
7. Wischmeyer P.E. Glutamine mode of action in critical illness. Crit Care Med 2007, 35(suppl 9):S541-S544.
8. Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. Composition on parenteral nutrition: glutamine; 2009. Available at: Accessed January 2011. http://www.criticalcarenutrition.com.
9. Singer P., Berger M.M., Van den Berghe G., Biolo G., Calder P., Forbes A., et al. ESPEN guidelines on parenteral nutrition: intensive care. Clin Nutr 2009, 28:387-400.
10. McClave S.A., Martindale R.G., Vanek V.W., McCarthy M., Roberts P., Taylor B., et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN 2009, 33:277-316.
11. Angstwurm M.W.A., Engelmann L., Zimmermann T., Lehmann C., Abel P., Strauss R., et al. Selenium in Intensive Care (SIC) study. Results of a prospective, randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock. Crit Care Med 2007, 35:118-126.
12. Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. Supplemental antioxidants nutrients: parenteral selenium; 2009. Available at: Accessed January 2011. http://www.criticalcarenutrition.com.
13. Avenell A, Andrew P. The SIGNET trial: a randomised controlled trial of glutamine and/or selenium supplemented parenteral nutrition in critical illness. Presented at the BAPEN 2009 " Malnutrition Matters" Conference; Cardiff, UK; October 14, 2009.
14. Manzanares W., Biestro A., Torre M.H., Galusso F., Facchín G., Hardy G. Clinical effects of high dose selenious acid in critically ill patients with systemic inflammation (abstract S36-4). JPEN 2009, 33:186.
15. Manzanares W., Biestro A., Galusso F., Torre M.H., Mañay N., Facchín G., et al. High-dose selenium for critically ill patients with systemic inflammation: a pilot study. Nutrition 2010, 26:634-640.
16. Heyland D.K., Dhaliwal R., Day A.G., Muscedere J., Dover J., Suchner U., et al. REducing Deaths due to Oxidative Stress (the REDOXS study): rationale and study design for a randomized trial of glutamine and antioxidant supplementation in critically ill patients. Proc Nutr Soc 2006, 65:250-263.
17. Ochoa J.B. Separating pharmaconutrition from classic nutrition goals. A necessary step. Crit Care Med 2008, 36:347-348.
18. Mizock B.A. Immunonutrition and critical illness: an update. Nutrition 2010, 26:701-707.
19. Meguid M.M., Goncalves C.G. Message to surgeons: the expected norm in elective complex GI cancer surgery is use of perioperative immunonutritional therapy that also saves hospital costs!. Ann Surg 2009, 249:364-365.
20. Dupertuis Y.M., Meguid M.M., Pichard C. Advancing from immunonutrition to a pharmaconutrition: a gigantic challenge. Curr Opin Clin Nutr Metab Care 2009, 12:398-403.
21. Hamani D., Kuhn M., Charrueau C., Waligora-Dupriet A.J., Neveux N., Butel M.J., et al. Interactions between ω-3 polyunsaturated fatty acids and arginine on nutritional and immunological aspects in severe inflammation. Clin Nutr 2010, 29:654-662.
22. Bansal V., Syres K.M., Makarenkova V., Brannon R., Matta B., Harbrecht B.G., et al. Interactions between fatty acids and arginine metabolism: implications for the design of immune-enhancing diets. JPEN 2005, 29:S75-80.
23. Pontes-Arruda A., Demichele S., Seth A., Singer P. The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data. JPEN 2008, 32:596-605.