Different effects of low- and high-dose insulin on ROS production and VEGF expression in bovine retinal microvascular endothelial cells in the presence of high glucose

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 249, Issue 9, 2011, Pages 1303-1310

  Wu, Haixiang ^a   Jiang, Chunhui ^a   Gan, Dekang ^a   Liao, Yujie ^a   Ren, Hui ^a   Sun, Zhongcui ^a   Zhang, Meng ^a   Xu, Gezhi ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Diabetic retinopathy; Insulin; Oxidative damage

Indexed keywords

ACETYLCYSTEINE; APOCYNIN; GLUCOSE; INSULIN; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 2; VASCULOTROPIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BOVINE RETINAL MICROVASCULAR ENDOTHELIAL CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETIC RETINOPATHY; DRUG EFFECT; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INSULIN TREATMENT; MICROVASCULAR ENDOTHELIAL CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; CATTLE; DIABETIC RETINOPATHY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GLUCOSE; HYPOGLYCEMIC AGENTS; INSULIN; ION CHANNELS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIAL PROTEINS; PRIMARY CELL CULTURE; REACTIVE OXYGEN SPECIES; RETINAL VESSELS; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 80052696654     PISSN: 0721832X     EISSN: 1435702X     Source Type: Journal    
DOI: 10.1007/s00417-011-1677-x     Document Type: Article

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