Improving liquid chromatography-mass spectrometry sensitivity using a subambient pressure ionization with nanoelectrospray (SPIN) interface

Journal of the American Society for Mass Spectrometry

Volumn 22, Issue 8, 2011, Pages 1318-1325

  Tang, Keqi ^a   Page, Jason S ^a   Marginean, Ioan ^a   Kelly, Ryan T ^a   Smith, Richard D ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

ESI; Ion source; LC MS; Sensitivity; Subambient pressure ESI

Indexed keywords

CHARGED CLUSTERS; COMPLEX SAMPLES; DESOLVATION; ELECTRICAL BREAKDOWN; ELECTROSPRAYS; ESI; LC-MS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; NANOELECTROSPRAY; NANOELECTROSPRAY IONIZATION; OPERATING PRESSURE; PRESSURE IONIZATION; REVERSED PHASE; SENSITIVITY; SPIN SOURCE; SUBAMBIENT PRESSURE ESI; TRYPTIC DIGESTS; WHOLE CELL;

ATMOSPHERIC IONIZATION; ATMOSPHERIC PRESSURE; ION SOURCES; IONIZATION OF LIQUIDS; IONS; LIQUIDS; MASS SPECTROMETRY; PHASE INTERFACES;

LIQUID CHROMATOGRAPHY;

PROTEIN; SOLVENT;

ARTICLE; ATMOSPHERIC PRESSURE; CELL LYSATE; CONTROLLED STUDY; ELECTROSPRAY; FLOW RATE; FREEZING; HYDROPHILICITY; INTERFACE PRESSURE; MASS SPECTROMETRY; REVERSED PHASE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS; SUBAMBIENT PRESSURE IONIZATION WITH NANOELECTROSPRAY INTERFACE;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CHROMATOGRAPHY, LIQUID; MOLECULAR SEQUENCE DATA; NANOTECHNOLOGY; PEPTIDE FRAGMENTS; PRESSURE; SENSITIVITY AND SPECIFICITY; SHEWANELLA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 80052681763     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-011-0135-7     Document Type: Article

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