Levetiracetam is associated with improved cognitive outcome for patients with intracranial hemorrhage

Neurocritical Care

Volumn 15, Issue 1, 2011, Pages 80-84

  Taylor, Scott ^a   Heinrichs, Robin J ^a   Janzen, Jeff M ^b   Ehtisham, As'ad ^c  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE WICHITA   (United States)

^b UNIVERSITY OF KANSAS   (United States)

^c Norton Health Care   (United States)

Author keywords

Cognitive outcome; Intracranial hemorrhage; Keywords Levetiracetam; Phenytoin; Seizure

Indexed keywords

ETIRACETAM; PHENYTOIN;

ADULT; AGED; ARTICLE; BRAIN HEMORRHAGE; COGNITION; COGNITIVE DEFECT; CONSCIOUSNESS LEVEL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GLASGOW COMA SCALE; HEART ARRHYTHMIA; HEMODYNAMICS; HOSPITAL DISCHARGE; HUMAN; INCIDENCE; INTENSIVE CARE; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCORING SYSTEM; SEIZURE; SIDE EFFECT; SUBARACHNOID HEMORRHAGE; SUBDURAL HEMATOMA;

ADULT; AGED; AGED, 80 AND OVER; ANTICONVULSANTS; COGNITION DISORDERS; FEMALE; HUMANS; INTRACRANIAL HEMORRHAGES; MALE; MIDDLE AGED; PHENYTOIN; PIRACETAM; RETROSPECTIVE STUDIES; SEIZURES; YOUNG ADULT;

EID: 80052646682     PISSN: 15416933     EISSN: 15560961     Source Type: Journal    
DOI: 10.1007/s12028-010-9341-6     Document Type: Article

References (17)

1. Lloyd-Jones D, Adams R, Carnethon M, et al. Heart disease and stroke statistics-2009 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119(3):e21-181.
2. Hart R, Byer J, Slaughter J, Hewett J, Easton J. Occurrence and implications of seizures in subarachnoid hemorrhage due to ruptured intracranial aneurysms. Neurosurgery. 1981;8(4):417-21. (Pubitemid 11104838)
3. Keränen T, Tapaninaho A, Hernesniemi J, Vapalahti M. Late epilepsy after aneurysm operations. Neurosurgery. 1985;17(6): 897-900. (Pubitemid 16178566)
4. Kotila M, Waltimo O. Epilepsy after stroke. Epilepsia. 1992; 33(3):495-8.
5. Olafsson E, Gudmundsson G, Hauser W. Risk of epilepsy in long-term survivors of surgery for aneurysmal subarachnoid hemorrhage: A population-based study in Iceland. Epilepsia. 2000;41(9):1201-5.
6. Ryvlin P, Montavont A, Nighoghossian N. Optimizing therapy of seizures in stroke patients. Neurology. 2006;67(12 Suppl 4):S3-9. (Pubitemid 44967989)
7. Chumnanvej S, Dunn I, Kim D. Three-day phenytoin prophylaxis is adequate after subarachnoid hemorrhage. Neurosurgery. 2007;60(1):99-102. (discussion 102-103). (Pubitemid 46102931)
8. Choudhari K, Kaliaperumal C. Three-day phenytoin prophylaxis is adequate after subarachnoid hemorrhage. Neurosurgery. 2007;61(6):E1340. (author reply E1340).
9. Zubkov A, Wijdicks E. Antiepileptic drugs in aneurysmal subarachnoid hemorrhage. Rev Neurol Dis. 2008;5(4):178-81.
10. Carpay J, Aldenkamp A, van Donselaar C. Complaints associated with the use of antiepileptic drugs: Results from a communitybased study. Seizure. 2005;14(3):198-206. (Pubitemid 40425269)
11. Naidech A, Kreiter K, Janjua N, et al. Phenytoin exposure is associated with functional and cognitive disability after subarachnoid hemorrhage. Stroke. 2005;36(3):583-7. (Pubitemid 40352567)
12. Díaz R, Sancho J, Serratosa J. Antiepileptic drug interactions. Neurologist. 2008;14(6 Suppl 1):S55-65.
13. Rogawski M. Diverse mechanisms of antiepileptic drugs in the development pipeline. Epilepsy Res. 2006;69(3):273-94. (Pubitemid 44209049)
14. Arif H, Buchsbaum R, Weintraub D, Pierro J, Resor SJ, Hirsch L. Patient-reported cognitive side effects of antiepileptic drugs: Predictors and comparison of all commonly used antiepileptic drugs. Epilepsy Behav. 2009;14(1):202-9.
15. Nau K, Divertie G, Valentino A, Freeman W. Safety and efficacy of levetiracetam for critically ill patients with seizures. Neurocrit Care. 2009;11(1):34-7.
16. Szaflarski J, Meckler J, Szaflarski M, Shutter L, Privitera M, Yates S. Levetiracetam use in critically ill patients. Neurocrit Care. 2007;7(2):140-7. (Pubitemid 350242663)
17. Lynch B, Lambeng N, Nocka K, et al. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci USA. 2004;101(26):9861-6. (Pubitemid 38869327)