Unusual reactivity of a potent platinum-acridine hybrid antitumor agent

ACS Medicinal Chemistry Letters

Volumn 2, Issue 9, 2011, Pages 687-691

  Graham, Leigh A ^a   Wilson, Gary M ^a   West, Tiffany K ^b   Day, Cynthia S ^a   Kucera, Gregory L ^b   Bierbach, Ulrich ^a  

^a WAKE FOREST UNIVERSITY   (United States)

^b WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

Author keywords

chelate; DNA interactions; nonsmall cell lung cancer; Platinum acridine; reactivity

Indexed keywords

ACRIDINE; ANTINEOPLASTIC AGENT; CYSTEINE; DNA; NITROGEN; NUCLEIC ACID BASE; PLATINUM;

ARTICLE; CANCER CELL; CELL PROLIFERATION; CYTOTOXICITY; DRUG CROSS REACTIVITY; HUMAN; IC 50; LUNG CANCER; PRIORITY JOURNAL; PROTON TRANSPORT; SUBSTITUTION REACTION;

EID: 80052629279     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml200104h     Document Type: Article

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