The multi-hit hypothesis of primary biliary cirrhosis: Polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis

Clinical and Experimental Immunology

Volumn 166, Issue 1, 2011, Pages 110-120

  Ambrosini, Y M ^a   Yang, G X ^a   Zhang, W ^a   Tsuda, M ^a   Shu, S ^a   Tsuneyama, K ^c   Leung, P S C ^a   Ansari, A A ^b   Coppel, R L ^d   Gershwin, M E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TOYAMA   (Japan)

^d MONASH UNIVERSITY   (Australia)

Author keywords

Liver fibrosis; Poly I:C; Primary biliary cirrhosis; TLRs; Xenobiotics

Indexed keywords

2 OCTYNOIC ACID; ACID; BOVINE SERUM ALBUMIN; CYTOKINE; MITOCHONDRION ANTIBODY; POLYINOSINIC POLYCYTIDYLIC ACID; PYRUVATE DEHYDROGENASE COMPLEX; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CD8+ T LYMPHOCYTE; CHOLANGITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; EXPERIMENTAL MODEL; FEMALE; HISTOPATHOLOGY; INNATE IMMUNITY; LIVER FIBROSIS; LYMPHOCYTIC INFILTRATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL;

ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNE DISEASES; CATTLE; CHOLANGITIS; CYTOKINES; DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE; DISEASE MODELS, ANIMAL; FATTY ACIDS, MONOUNSATURATED; FEMALE; HUMANS; IMMUNIZATION; LIVER; LIVER CIRRHOSIS, BILIARY; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; POLY I-C; SERUM ALBUMIN; TOLL-LIKE RECEPTOR 3;

EID: 80052619577     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2011.04453.x     Document Type: Article

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