Efficient accumulation of oleic acid in Saccharomyces cerevisiae caused by expression of rat elongase 2 gene (rELO2) and its contribution to tolerance to alcohols

Applied Microbiology and Biotechnology

Volumn 91, Issue 6, 2011, Pages 1593-1600

  Yazawa, Hisashi ^a   Kamisaka, Yasushi ^a   Kimura, Kazuyoshi ^a   Yamaoka, Masakazu ^a   Uemura, Hiroshi ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Alcohol resistance; rELO2; Saccharomyces cerevisiae; Unsaturated fatty acids

Indexed keywords

2-PROPANOL; DESATURASE; ELONGASE; ETHANOL TOLERANCE; FATTY ACID COMPOSITION; HIGH CONCENTRATION; INITIAL CONCENTRATION; N-BUTANOL; N-PROPANOL; PALMITOLEIC ACID; RELO2; S.CEREVISIAE;

ETHANOL; GENE EXPRESSION; OLEIC ACID; RATS; UNSATURATED FATTY ACIDS;

YEAST;

2 PROPANOL; ALCOHOL; BUTANOL; ELONGASE 2; FATTY ACID DERIVATIVE; FUEL; OLEIC ACID; PALMITOLEIC ACID; UNCLASSIFIED DRUG; VACCENIC ACID;

ALCOHOL; BIOACCUMULATION; BIOCHEMICAL COMPOSITION; CONCENTRATION (COMPOSITION); ENZYME ACTIVITY; FATTY ACID; GENE EXPRESSION; RODENT; TOLERANCE; TRANSFORMATION; YEAST;

ALCOHOL PRODUCTION; ALCOHOL TOLERANCE; ARTICLE; CONCENTRATION (PARAMETERS); GENE EXPRESSION; LIPID COMPOSITION; LIPID STORAGE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE;

ACETYLTRANSFERASES; ALCOHOLS; ANIMALS; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION; OLEIC ACID; RATS; SACCHAROMYCES CEREVISIAE;

RATTUS; SACCHAROMYCES CEREVISIAE;

EID: 80052611253     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3410-4     Document Type: Article

References (37)

1. A Aguilera T Benitez 1986 Ethanol-sensitive mutants of Saccharomyces cerevisiae Arch Microbiol 143 337 344 10.1007/BF00412799 1:CAS:528: DyaL28XosFagsA%3D%3D (Pubitemid 16146171)
2. H Alexandre I Rousseaux C Charpentier 1994 Ethanol adaptation mechanisms in Saccharomyces cerevisiae Biotechnol Appl Biochem 20 173 183 1:CAS:528:DyaK2cXmsFWis70%3D (Pubitemid 2142457)
3. H Alexandre V Ansanay-Galeote S Dequin B Blondin 2001 Global gene expression during short-term ethanol stress in Saccharomyces cerevisiae FEBS Lett 498 98 103 10.1016/S0014-5793(01)02503-0 1:CAS:528:DC%2BD3MXktVKqs7g%3D (Pubitemid 32522899)
4. PV Attfield 1997 Stress tolerance: the key to effective strains of industrial baker's yeast Nat Biotechnol 15 1351 1357 10.1038/nbt1297-1351 1:CAS:528:DyaK2sXotFWjtLw%3D (Pubitemid 28022728)
5. MJ Beavan C Charpentier AH Rose 1982 Production and tolerance of ethanol in relation to phospholipid fatty acyl composition in Saccharomyces cerevisiae J Gen Microbiol 128 1447 1455 (Pubitemid 12013259)
6. GP Casey WE Ingledew 1986 Ethanol tolerance of yeasts CRC Crit Rev Microbiol 13 219 280 10.3109/10408418609108739 1:CAS:528:DyaL28Xmt1CntrY%3D
7. K Fujita A Matsuyama Y Kobayashi H Iwahashi 2004 Comprehensive gene expression analysis of the response to straight-chain alcohols in Saccharomyces cerevisiae using cDNA microarray J Appl Microbiol 97 57 67 10.1111/j.1365-2672. 2004.02290.x 1:CAS:528:DC%2BD2cXmtl2nurw%3D (Pubitemid 38869882)
8. K Fujita A Matsuyama Y Kobayashi H Iwahashi 2006 The genome-wide screening of yeast deletion mutants to identify the genes required for tolerance to ethanol and other alcohols FEMS Yeast Res 6 744 750 10.1111/j.1567-1364. 2006.00040.x 1:CAS:528:DC%2BD28Xotlymtr4%3D (Pubitemid 44049993)
9. D Fujiwara H Yoshimoto H Sone S Harashima Y Tamai 1998 Transcriptional co-regulation of Saccharomyces cerevisiae alcohol acetyltransferase gene, ATF1 and delta-9 fatty acid desaturase gene, OLE1 by unsaturated fatty acids Yeast 14 711 721 10.1002/(SICI)1097-0061(19980615)14:8<711::AID-YEA263>3.0.CO;2-8 1:CAS:528:DyaK1cXktFWntr4%3D (Pubitemid 28277568)
10. JE Hill AM Myers TJ Koerner A Tzagoloff 1986 Yeast/E. coli shuttle vectors with multiple unique restriction sites Yeast 2 163 167 10.1002/yea.320020304 1:CAS:528:DyaL1cXhs1alsLo%3D
11. K Inagaki T Aki Y Fukuda S Kawamoto S Shigeta K Ono O Suzuki 2002 Identification and expression of a rat fatty acid elongase involved in the biosynthesis of C18 fatty acids Biosci Biotech Biochem 66 613 621 10.1271/bbb.66.613 1:CAS:528:DC%2BD38Xisl2mur4%3D (Pubitemid 39251020)
12. T Inoue H Iefuji T Fujii H Soga K Satoh 2000 Cloning and characterization of a gene complementing the mutation of an ethanol-sensitive mutant of sake yeast Biosci Biotech Biochem 64 229 236 10.1271/bbb.64.229 1:CAS:528: DC%2BD3cXhvVCjsbg%3D
13. H Ito Y Fukuda K Murata A Kimura 1983 Transformation of intact yeast cells treated with alkali cations J Bacteriol 153 163 168 1:CAS:528: DyaL3sXht1alsLs%3D (Pubitemid 13119852)
14. RP Jones 1989 Biological principles for the effects of ethanol Enzyme Microbial Technol 11 130 153 10.1016/0141-0229(89)90073-2 1:CAS:528: DyaL1MXhsFSqtbg%3D (Pubitemid 19076655)
15. N Kabelitz PM Santos HJ Heipieper 2003 Effect of aliphatic alcohols on growth and degree of saturation of membrane lipids in Acinetobacter calcoaceticus FEMS Microbiol Lett 220 223 227 10.1016/S0378-1097(03)00103-4 1:CAS:528:DC%2BD3sXisV2mt7k%3D (Pubitemid 36378975)
16. K Kainou Y Kamisaka K Kimura H Uemura 2006 Isolation of Δ12 and ω3-fatty acid desaturase genes from the yeast Kluyveromyces lactis and their heterologous expression to produce linoleic and α-linolenic acids in Saccharomyces cerevisiae Yeast 23 605 612 10.1002/yea.1378 1:CAS:528: DC%2BD28XnvF2ht7c%3D (Pubitemid 44150708)
17. S Kajiwara A Shirai T Fujii T Toguri K Nakamura K Ohtaguchi 1996 Polyunsaturated fatty acid biosynthesis in Saccharomyces cerevisiae: expression of ethanol tolerance and the FAD2 gene from Arabidopsis thaliana Appl Environ Microbiol 62 4309 4313 1:CAS:528:DyaK28Xnt1agtL4%3D (Pubitemid 26399419)
18. S Kajiwara T Aritomi K Suga K Ohtaguchi O Kobayashi 2000 Overexpression of the OLE1 gene enhances ethanol fermentation by Saccharomyces cerevisiae Appl Microbiol Biotechnol 53 568 574 10.1007/s002530051658 1:CAS:528: DC%2BD3cXktVCqtr8%3D (Pubitemid 30341408)
19. HS Kim NR Kim W Choi 2011 Total fatty acid content of the plasma membrane of Saccharomyces cerevisiae is more responsible for ethanol tolerance than the degree of unsaturation Biotechnol Lett 33 509 515 10.1007/s10529-010-0465-8 1:CAS:528:DC%2BC3MXitFGnt70%3D
20. S Kubota I Takeo K Kume M Kanai A Shitamukai M Mizunuma T Miyakawa H Shimoi H Iefuji D Hirata 2004 Effect of ethanol on cell growth of budding yeast: genes that are important for cell growth in the presence of ethanol Biosci Biotech Biochem 68 968 972 10.1271/bbb.68.968 1:CAS:528:DC%2BD2cXjvFersbs%3D (Pubitemid 39251478)
21. D Lloyd S Morrell HN Carlsen H Degn PE James CC Rowlands 1993 Effects of growth with ethanol on fermentation and membrane fluidity of Saccharomyces cerevisiae Yeast 9 825 833 10.1002/yea.320090803 1:CAS:528:DyaK3sXmsVGgu7Y%3D (Pubitemid 23255831)
22. M Ma ZL Liu 2010 Mechanisms of ethanol tolerance in Saccharomyces cerevisiae Appl Microbiol Biotechnol 87 829 845 10.1007/s00253-010-2594-3 1:CAS:528:DC%2BC3cXnsFGmsbs%3D
23. Y Matsufuji S Fujimura T Ito M Nishizawa T Miyaji J Nakagawa T Ohyama T Tomizuka T Nakagawa 2008 Acetaldehyde tolerance in Saccharomyces cerevisiae involves the pentose phosphate pathway and oleic acid biosynthesis Yeast 25 825 833 10.1002/yea.1637 1:CAS:528:DC%2BD1MXis1WktQ%3D%3D
24. P Mishra R Prasad 1989 Relationship between ethanol tolerance and fatty acyl composition of Saccharomyces cerevisiae Appl Microbiol Biotechnol 30 294 298 10.1007/BF00256221 1:CAS:528:DyaL1MXitFSqtr8%3D
25. Y Ogawa A Nitta H Uchiyama T Imamura H Shimoi K Ito 2000 Tolerance mechanism of the ethanol-tolerant mutant of sake yeast J Biosci Bioeng 90 313 320 1:CAS:528:DC%2BD3cXotFejsrs%3D
26. JL Ramos E Duque MT Gallegos P Godoy MI Ramos-Gonzalez A Rojas W Teran A Segura 2002 Mechanisms of solvent tolerance in gram-negative bacteria Annu Rev Microbiol 56 743 768 10.1146/annurev.micro.56.012302.161038 1:CAS:528: DC%2BD38Xos1Gisbo%3D (Pubitemid 35217473)
27. GJ Salter DB Kell 1995 Solvent selection for whole cell biotransformations in organic media Crit Rev Biotechnol 15 139 177 10.3109/07388559509147404 1:CAS:528:DyaK2MXnt1Orsrw%3D
28. Sambrook J, Russell DW (2001) Molecular cloning: a laboratory manual, 3rd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor
29. Sherman F, Fink GR, Hicks JB (1986) Methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor
30. J Sikkema JA de Bont B Poolman 1995 Mechanisms of membrane toxicity of hydrocarbons Microbiol Rev 59 201 222 1:CAS:528:DyaK2MXms1SntLw%3D
31. T Takahashi H Shimoi K Ito 2001 Identification of genes required for growth under ethanol stress using transposon mutagenesis in Saccharomyces cerevisiae Mol Genet Genomics 265 1112 1119 10.1007/s004380100510 1:CAS:528:DC%2BD3MXmtlShu74%3D (Pubitemid 32702185)
32. DS Thomas JA Hossack AH Rose 1978 Plasma-membrane lipid composition and ethanol tolerance in Saccharomyces cerevisiae Arch Microbiol 117 239 245 10.1007/BF00738541 1:CAS:528:DyaE1cXlsFyjsro%3D (Pubitemid 8362075)
33. H Uemura RB Wickner 1988 Suppression of chromosomal mutations affecting M1 virus replication in Saccharomyces cerevisiae by a variant of a viral RNA segment (L-A) that encodes coat protein Mol Cell Biol 8 938 944 1:CAS:528:DyaL1cXht1Gnur0%3D
34. F van Voorst J Houghton-Larsen L Jonson MC Kielland-Brandt A Brandt 2006 Genome-wide identification of genes required for growth of Saccharomyces cerevisiae under ethanol stress Yeast 23 351 359 10.1002/yea.1359
35. T Vernet D Dignard DY Thomas 1987 A family of yeast expression vectors containing the phage f1 intergenic region Gene 52 225 233 10.1016/0378-1119(87) 90049-7 1:CAS:528:DyaL2sXktlCjt7s%3D (Pubitemid 17090751)
36. H Yazawa H Iwahashi H Uemura 2007 Disruption of URA7 and GAL6 improves the ethanol tolerance and fermentation capacity of Saccharomyces cerevisiae Yeast 24 551 560 10.1002/yea.1492 1:CAS:528:DC%2BD2sXot1elurs%3D (Pubitemid 47082722)
37. KM You CL Rosenfield DC Knipple 2003 Ethanol tolerance in the yeast Saccharomyces cerevisiae is dependent on cellular oleic acid content Appl Environ Microbiol 69 1499 1503 10.1128/AEM.69.3.1499-1503.2003 1:CAS:528:DC%2BD3sXitlCls74%3D (Pubitemid 36314287)