Polyunsaturated fatty acid biosynthesis in Saccharomyces cerevisiae: Expression of ethanol tolerance and the FAD2 gene from Arabidopsis thaliana

Applied and Environmental Microbiology

Volumn 62, Issue 12, 1996, Pages 4309-4313

  Kajiwara, Susumu ^a   Shirai, Atsuya ^a   Fujii, Toshio ^b   Toguri, Toshihiro ^b   Nakamura, Katsumi ^b   Ohtaguchi, Kazuhisa ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b KIRIN BREWERY CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE; MEMBRANE LIPID; PALMITOLEIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; POLYUNSATURATED FATTY ACID;

ALCOHOL TOLERANCE; ARABIDOPSIS; ARTICLE; BACTERIAL MEMBRANE; CELL VIABILITY; FATTY ACID SYNTHESIS; GAS LIQUID CHROMATOGRAPHY; GENE EXPRESSION; LIPID ANALYSIS; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PROMOTER REGION; SACCHAROMYCES CEREVISIAE; TEMPERATURE DEPENDENCE;

ARABIDOPSIS; ARABIDOPSIS THALIANA; BACTERIA (MICROORGANISMS); SACCHAROMYCES CEREVISIAE;

EID: 0030000834     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.62.12.4309-4313.1996     Document Type: Article

References (27)

1. Arondel, V., B. Lemieux, I. Hwang, S. Gibson, H. M. Goodman, and C. Somerville. 1992. Map-based cloning of a gene controlling omega-3 fatty acid desaturation in Arabidopsis. Science 258:1353-1355.
2. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1987. Current protocols in molecular biology. Greene Publishing Associates and Wiley-Interscience, John Wiley & Sons, Inc., New York.
3. Beavan, M. J., C. Charpentier, and A. H. Rose. 1982. Production and tolerance of ethanol in relation to phospholipid fatty acyl composition in Saccharomyces cerevisiae. J. Gen. Microbiol. 128:1447-1455.
4. Bossie, M. A., and C. E. Martin. 1989. Nutritional regulation of yeast Δ-9 fatty acid desaturase activity. J. Bacteriol. 171:6409-6413.
5. Browse, J., and C. Somerville. 1991. Glycerolipid synthesis: biochemistry and regulation. Annu. Rev. Plant Physiol. Plant Mol. Biol. 42:467-506.
6. Carman, G. M., and G. M. Zeimetz. 1996. Regulation of phospholipid biosynthesis in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 271:13293-13296.
7. Casey, G. P., and W. M. Ingledew. 1986. Ethanol tolerance in yeasts. Crit. Rev. Microbiol. 13:219-280.
8. Covello, P. S., and D. W. Reed. 1996. Functional expression of the extraplastidial Arabidopsis thaliana oleate desaturase gene (FAD2) in Saccharomyces cerevisiae. Plant Physiol. 111:223-226.
9. Ferrante, G., and M. Kates. 1983. Pathways for desaturation of oleoyl chains in Candida lipolytica. Can. J. Biochem. Cell Biol. 61:1191-1196.
10. Heinz, E. 1993. Biosynthesis of polyunsaturated fatty acids, p. 33-89. In T. S. J. Moore (ed.), Lipid metabolism in plants - 1993. CRC Press Inc., Boca Raton, Fla.
11. Hunter, K., and A. H. Rose. 1972. Lipid composition of Saccharomyces cerevisiae as influenced by growth temperature. Biochim. Biophys. Acta 260:639-653.
12. Jones, R. P. 1989. Biological principles for the effects of ethanol. Enzyme Microb. Technol. 11:130-153.
13. Jones, R. P., and P. F. Greenfield. 1987. Ethanol and fluidity of the yeast plasma membrane. Yeast 3:223-232.
14. 5 in Δ-12 desaturation of oleic acid by microsomes of safflower (Carthamus tinctorius L.). Arch. Biochem. Biophys. 284:431-436.
15. Mishra, P., and R. Prasad. 1988. Role of phospholipid head groups in ethanol tolerance of Saccharomyces cerevisiae. J. Gen. Microbiol. 134:3205-3211.
16. Mishra, P., and R. Prasad. 1989. Relationship between ethanol tolerance and fatty acyl composition of Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol. 30:294-298.
17. 5-like domain is linked to the carboxyl terminus of the Saccharomyces cerevisiae Δ-9 fatty acid desaturase. J. Biol. Chem. 270:29766-29772.
18. Murphy, D. J., I. E. Woodrow, and K. D. Mukherjee. 1985. Substrate specificities of the enzymes of the oleate desaturase system from photosynthetic tissue. Biochem. J. 225:267-270.
19. Okuley, J., J. Lightner, K. Feldmann, N. Yadav, E. Lark, and J. Browse. 1994. Arabidopsis FAD2 gene encodes the enzyme that is essential for poly-unsaturated lipid synthesis. Plant Cell 6:147-158.
20. Ratledge, C., and C. T. Evans. 1991. Lipids and their metabolism, p. 367-456. In A. H. Rose and J. S. Harrison (ed.), The yeasts, 2nd ed., vol. 4. Academic Press Limited, London.
21. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
22. Somerville, C., and J. Browse. 1991. Plant lipids: metabolism, mutants, and membranes. Science 252:80-87.
23. St. John, T. P., and R. W. Davis. 1981. The organization and transcription of the galactose gene cluster of Saccharomyces. J. Mol. Biol. 152:285-315.
24. Stymne, S., and G. Glad. 1981. Acyl exchange between oleoyl-CoA and phosphatidylcholine in microsomes of developing soya bean cotyledons and its role in fatty acid desaturation. Lipids 16:298-305.
25. Suutari, M., and S. Laakso. 1994. Microbial fatty acids and thermal adaptation. Crit. Rev. Microbiol. 20:285-328.
26. Thomas, D. S., J. A. Hossack, and A. H. Rose, 1978. Plasma-membrane lipid composition and ethanol tolerance in Saccharomyces cerevisiae. Arch. Microbiol. 117:239-245.
27. Yadav, N. S., A. Wierzbicki, M. Aegerter, C. S. Caster, L. Perez-Grau, A. J. Kinney, W. D. Hitz, J. R. B. Booth, Jr., B. Schwelger, K. L. Stecca, S. M. Allen, M. Blackwell, R. S. Reiter, T. J. Carlson, S. H. Russell, K. A. Feldmann, J. Pierce, and J. Browse. 1993. Cloning of higher plant ω-3 fatty acid desaturases. Plant Physiol. 103:467-476.