Multicentric breast cancer: Clonality and prognostic studies

Breast Cancer Research and Treatment

Volumn 129, Issue 3, 2011, Pages 703-716

  Eeles, R ^a,b   Knee, G ^c   Jhavar, S ^a,b   Mangion, J ^a,d   Ebbs, S ^b   Gui, G ^b   Thomas, S ^e   Coppen, M ^e   A'Hern, R ^a   Gray, S ^b   Cooper, C ^a   Bartek, J ^f,g   Yarnold, J ^a,b  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c KINGSTON HOSPITAL   (United Kingdom)

^d Bioinformatics Europe   (United Kingdom)

^e MAYDAY UNIVERSITY HOSPITAL   (United Kingdom)

^f DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^g PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

Breast cancer; Clonality; Multicentric; Prognosis; TP53

Indexed keywords

PROTEIN P53;

ARTICLE; BREAST CANCER; CANCER SURVIVAL; CLINICAL ARTICLE; CLONAL VARIATION; CONTROLLED STUDY; DNA POLYMORPHISM; DNA STRAND; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOLECULAR GENETICS; MULTIPLE CANCER; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CASE-CONTROL STUDIES; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROGNOSIS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 80052599011     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1230-3     Document Type: Article

References (41)

1. H Jiang HC Reinhardt J Bartkova J Tommiska C Blomqvist H Nevanlinna J Bartek MB Yaffe MT Hemann 2009 The combined status of ATM and p53 link tumor development with therapeutic response Genes Dev 23 1895 1909 19608766 10.1101/gad.1815309 1:CAS:528:DC%2BD1MXhtVegurbO
2. J Bartek R Iggo J Gannon DP Lane 1990 Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines Oncogene 5 893 899 1694291 1:CAS:528:DyaK3cXkvFalsbw%3D
3. B Vogelstein ER Fearon SR Hamilton AC Preisinger HF Willard AM Michelson AD Riggs S Orkin 1987 Clonal analysis using recombinant DNA probes from the X-chromosome Cancer Res 47 4806 4813 2887283 1:CAS:528:DyaL2sXlvFGrs70%3D (Pubitemid 17143023)
4. DG Gilliland KL Blanchard J Levy S Perrin HF Bunn 1991 Clonality in myeloproliferative disorders: analysis by means of the polymerase chain reaction Proc Natl Acad Sci USA 88 6848 6852 1862109 10.1073/pnas.88.15.6848 1:CAS:528:DyaK3MXlvVSms74%3D (Pubitemid 21915047)
5. M Camargo N Wang 1980 Cytogenetic evidence for the absence of an inactivated X chromosome in a human female (XX) breast carcinoma cell line Hum Genet 55 81 85 7450759 10.1007/BF00329131 1:STN:280:DyaL3M%2Fpt1Cltg%3D%3D (Pubitemid 10090194)
6. RA Eeles J Bartkova DP Lane J Bartek 1993 The role of TP53 in breast cancer development Cancer Surv 18 57 75 8013000 1:CAS:528:DyaK2cXksl2lu7o%3D (Pubitemid 24110633)
7. SJ Done NCR Arneson H Ozcelik M Redston IL Andrulis 1998 p53 Mutations in mammary ductal carcinoma in situ but not in epithelial hyperplasias Cancer Res 58 785 789 9485035 1:CAS:528:DyaK1cXht1anu70%3D (Pubitemid 28099492)
8. MD Lagios 1997 Multicentricity of breast carcinoma demonstrated by routine correlated serial subgross and radiographic examination Cancer 40 1726 1734 10.1002/1097-0142(197710)40:4<1726::AID-CNCR2820400449>3.0.CO;2-O
9. LA Cannon-Albright A Thomas DE Goldgar K Gholami K Rowe M Jacobsen WP McWhorter MH Skolnick 1994 Familiality of cancer in Utah Cancer Res 54 2378 2385 8162584 1:STN:280:DyaK2c3hsFWktg%3D%3D (Pubitemid 24138728)
10. JM Kurtz J Jacquemier R Amalric H Brandone Y Ayme D Hans C Bressac JM Spitalier 1990 Breast-conserving therapy for macroscopically multiple cancers Ann Surg 212 38 44 2363602 10.1097/00000658-199007000-00006 1:STN:280: DyaK3czgtlSgsw%3D%3D (Pubitemid 20215913)
11. JE Eyfjord S Thorlacius M Steinarsdottir R Valgardsdottir HM Ogmundsdottir K Anamthawat-Jonsson 1995 p53 abnormalities and genomic instability in primary human breast carcinomas Cancer Res 55 646 651 7530599 1:STN:280:DyaK2M7js1antg%3D%3D
12. RL Egan 1982 Multicentric breast carcinomas: clinical-radiographic- pathologic whole organ studies and 10-year survival Cancer 49 1123 1130 6277457 10.1002/1097-0142(19820315)49:6<1123::AID-CNCR2820490610>3.0.CO;2-R 1:STN:280:DyaL387js1Khsw%3D%3D (Pubitemid 12187811)
13. J Bartek J Bartkova B Vojtesek Z Staskova J Lukas J Rejithar J Kovarik CA Midgley JV Gannon DP Lane 1991 Aberrant expression of the TP53 oncoprotein is a common feature of a wide spectrum of human malignancies Oncogene 6 1699 1703 1923535 1:CAS:528:DyaK3MXmsFejtL4%3D (Pubitemid 21924277)
14. B Vojtesek J Bartek CA Midgley DP Lane 1992 An immunochemical analysis of human p53: new monoclonal antibodies and epitope mapping using recombinant p53 J Immunol Methods 151 237 244 1378473 10.1016/0022-1759(92)90122-A 1:CAS:528:DyaK38XlsVKlsr8%3D
15. CA Midgley C Fisher J Bartek B Vojtesek DP Lane DM Barnes 1992 Expression of p53 in bacteria: generation of polyclonal antiserum and analysis of p53 expression in human tumors J Cell Sci 101 183 189 1569122 1:CAS:528: DyaK3sXpslChsA%3D%3D
16. SE Goelz SR Hamilton B Vogelstein 1985 Purification of DNA from formaldehyde fixed and paraffin embedded human tissue Biochem Biophys Res Commun 130 118 126 2992457 10.1016/0006-291X(85)90390-0 1:CAS:528:DyaL2MXltVWgtr4%3D (Pubitemid 15249008)
17. RK Saiki DH Gelfand S Stoffel SJ Scharf R Higuchi GT Horn KB Mullis HA Erlich 1998 Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase Science 239 487 491 10.1126/science.2448875
18. L Dubeau LA Chandler JR Gralow PW Nichols PA Jones 1986 Southern blot analysis of DNA extracted from formalin-fixed pathology specimens Cancer Res 46 2964 2969 3009004 1:CAS:528:DyaL28XksFOgur4%3D (Pubitemid 16074313)
19. M Orita H Iwahana H Kanazawa K Hayashi T Sekiya 1989 Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms Proc Natl Acad Sci USA 86 2766 2770 2565038 10.1073/pnas.86.8.2766 1:CAS:528:DyaL1MXkt1SgtL0%3D (Pubitemid 19112622)
20. Eeles RA (2000) Germline and somatic mutations in the TP53 gene in breast and other cancers. PhD Thesis, University of London, UK
21. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory Press, NY, USA
22. F Sanger S Nicklen AR Coulson 1997 DNA sequencing with chain-terminating inhibitors Proc Natl Acad Sci USA 74 5463 5467 10.1073/pnas.74.12.5463
23. WI Wood J Gitscher LA Lasky RM Lawn 1985 Base composition-independent hybridisation in tertramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries Proc Natl Acad Sci USA 82 1585 1588 3856838 10.1073/pnas.82.6.1585 1:CAS:528:DyaL2MXhvVSiu7g%3D (Pubitemid 15079437)
24. MR Stratton S Moss W Warren H Patterson J Clark C Fisher CD Fletcher A Ball M Thomas BA Gusterson 1990 Mutation of the p53 gene in human soft tissue sarcomas: association with abnormalities of the RB1 gene Oncogene 5 1297 1301 2216456 1:CAS:528:DyaK3cXmt1GmtL8%3D
25. DR Cox 1972 Regression models and life tables (with discussion) J R Stat Soc Ser B 34 187 220
26. IB Runnebaum M Nagarajan M Bowman D Soto S Sukumar 1991 Mutations in p53 as potential molecular markers for human breast cancer Proc Natl Acad Sci USA 88 10657 10661 1961733 10.1073/pnas.88.23.10657 1:CAS:528:DyaK38XotFaruw%3D%3D (Pubitemid 21915896)
27. R Mazars L Spinardi M BenCheikh J Simony-Lafontaine P Jeanteur C Theillet 1992 p53 mutations occur in aggressive breast cancer Cancer Res 52 3918 3923 1617667 1:CAS:528:DyaK38XlsVyhsb8%3D
28. JS Kovach RM McGovern JD Cassady SK Swanson LE Wold B Vogelstein SS Sommer 1991 Direct sequencing from touch preparations of human carcinomas: analysis of p53 mutations in breast carcinomas J Natl Cancer Inst 83 1004 1009 1712853 10.1093/jnci/83.14.1004 1:CAS:528:DyaK3MXlslKlt7g%3D
29. C Coles A Condie U Chetty CM Steel HJ Evans J Prosser 1992 TP53 mutations in breast cancer Cancer Res 52 5291 5298 1394133 1:CAS:528:DyaK38XmsV2gsrs%3D
30. AM Thompson TJ Anderson A Condie J Prosser U Chetty DC Carter HJ Evans CM Steel 1992 p53 allele losses, mutations and expression in breast cancer and their relationship to clinico-pathological parameters Int J Cancer 50 528 532 1537617 10.1002/ijc.2910500405 1:CAS:528:DyaK38XlvV2itbk%3D
31. J Jacquemier JP Moles F Penault-Llorca J Adelaide M Torrente P Viens D Birnbaum C Theillet 1994 TP53 immunohistochemical analysis in breast cancer with four monoclonal antibodies: comparison of staining and PCR-SSCP results Br J Cancer 69 846 852 7514027 10.1038/bjc.1994.164 1:STN:280:DyaK2c3jsFCgtw%3D%3D (Pubitemid 24140662)
32. S Gretarsdottir L Trygyadottir JG Jonasson H Sigurdsson K Olafsdottir BA Agnarsson H Ogmundsdottir J Eyfjord 1996 TP53 mutation analysis on breast carcinomas: a study of paraffin-embedded archival material Br J Cancer 74 555 561 8761369 10.1038/bjc.1996.400 1:CAS:528:DyaK28XlvVWjt74%3D (Pubitemid 26279049)
33. J Bartkova Z Horejsi K Koed A Kramer F Tort K Zieger P Guldberg M Sehested JM Nesland C Lukas T Orntoft J Lukas J Bartek 2005 DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis Nature 434 864 870 15829956 10.1038/nature03482 1:CAS:528:DC%2BD2MXjtFOms7k%3D (Pubitemid 40558993)
34. A Hartmann H Blaszyk RM McGovern JJ Schroeder J Cunningham EM De Vries JS Kovach SS Sommer 1995 p53 gene mutations inside and outside of exons 5-8: the patterns differ in breast and other cancers Oncogene 10 681 688 7862445 1:CAS:528:DyaK2MXktF2lsbw%3D
35. S Sjogren M Inganas T Norberg A Lindgren H Nordgren L Holmberg J Bergh 1996 The p53 gene in breast cancer: prognostic value of complementary DNA sequencing versus immunohistochemistry J Natl Cancer Inst 88 173 182 8632491 10.1093/jnci/88.3-4.173 1:STN:280:DyaK283jtF2gsA%3D%3D (Pubitemid 26065829)
36. S Noguchi K Motomura H Inaji S Imaoka H Koyama 1992 Clonal analysis of human breast cancer by means of the polymerase chain reaction Cancer Res 52 6594 6597 1423305 1:CAS:528:DyaK3sXhs1Khtbw%3D
37. LP Middleton G Vlastos NQ Mirza SE Singletary AA Sahin 2002 Multicentric mammary carcinoma Cancer 94 1910 1916 11932891 10.1002/cncr.10452 (Pubitemid 34270042)
38. G Vlastos IT Rubio NQ Mirza LA Newman R Aurora J Alderfer AU Buzdar SE Singletary 2000 Impact of multicentricity on clinical outcome in patients with T1-2, N0-1, M0 Breast cancer Ann Surg Oncol 7 8 581 587 11005556 1:STN:280:DC%2BD3cvltVGksA%3D%3D
39. Eckert KA, Kunkel TA (1991) The fidelity of DNA polymerases used in the polymerase chain reactions. In: McPherson MJ, Quirke P, Taylor GR (eds) PCR: a practical approach. Oxford University Press, New York, pp 225-245
40. EB Claus N Risch WD Thompson 1991 Genetic analysis of breast cancer in the cancer and steroid hormone study Am J Hum Genet 48 232 1990835 1:STN:280:DyaK3M7hvV2gsA%3D%3D
41. R Yeruchalmi H Kennecke R Woods IA Olivotto C Speers KA Gelmon 2009 Does multicentric/multifocal breast cancer differ from unifocal breast cancer? An analysis of survival and contralateral breast cancer incidence Breast Cancer Res Treat 117 365 370 10.1007/s10549-008-0265-1