p53 mutations in mammary ductal carcinoma in situ but not in epithelial hyperplasias

Cancer Research

Volumn 58, Issue 4, 1998, Pages 785-789

  Done, Susan J ^a,b   Arneson, Nona C R ^b   Özçelik, Hilmi ^a,b   Redston, Mark ^a,b   Andrulis, Irene L ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; BREAST HYPERPLASIA; CANCER INVASION; FEMALE; GENE MUTATION; GENETIC MARKER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

ADULT; AGED; BREAST DISEASES; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; DISEASE PROGRESSION; GENES, P53; HUMANS; HYPERPLASIA; MIDDLE AGED; MUTATION;

EID: 0032520062     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Page, D. L., Dupont, W. D., Rogers, L. W., and Rados, M. S. Atypical hyperplastic lesions of the female breast. A long-term follow-up study. Cancer (Phila.), 55: 2698-2708, 1985.
2. Page, D. L., Dupont, W. D., Rogers, L. W., and Landenberger, M. Intraductal carcinoma of the breast: follow-up after biopsy only. Cancer (Phila.), 49: 751-758, 1982.
3. Dupont, W. D., and Page, D. L. Risk factors for breast cancer in women with proliferative breast disease. N. Engl. J. Med., 312: 146-151, 1985.
4. Elledge, R. M., and Allred, D. C. The p53 tumor suppressor gene in breast cancer. Breast Cancer Res. Treat., 32: 39-47, 1994.
5. Chitemerere, M., Andersen, T. I., Holm, R., Karlsen, F., Børresen, A-L., and Nesland, J. M. TP53 alterations in atypical ductal hyperplasia and ductal carcinoma in situ of the breast. Breast Cancer Res. Treat., 41: 103-109, 1996.
6. Millikan, R., Hulka, B., Thor, A., Zhang, Y., Edgerton, S., Zhang, X., Pei, H., He, M., Wold, L., Melton, L. J., Ballard, D., Conway, K., and Liu, E. T. p53 mutations in benign breast tissue. J. Clin. Oncol., 13: 2293-2300, 1995.
7. Rajan, P. B., Scott, D. J., Perry, R. H., and Griffith, C. D. M. p53 protein expression in ductal carcinoma in situ (DCIS) of the breast. Breast Cancer Res. Treat., 42: 283-290, 1997.
8. Allred, D. C., O'Connell, P., Fuqua, S. A. W., and Osborne, C. K. Immunohistochemical studies of early breast cancer evolution. Breast Cancer Res. Treat., 32: 13-18, 1994.
9. Bloom, H. J. G., and Richardson, W. W. Histological grading and prognosis in breast cancer. A study of 1409 cases of which 359 have been followed for 15 years. Br. J. Cancer, 11: 359-377, 1957.
10. Silverstein, M. J., Poller, D. N., Waisman, J. R., Colbum, W. J., Barth, A., Gierson, E. D., Lewinsky, B., Gamagami, P., and Slamon, D. J. Prognostic classification of breast ductal carcinoma-in situ. Lancet, 345: 1154-1157, 1995.
11. Özçelik, H., and Andrulis, I. L. Multiplex PCR-SSCP for simultaneous screening for mutations in several exons of p53. Biotechniques, 18: 742-744, 1995.
12. Özçelik, H., Mousses, S., and Andrulis, I. L. Low levels of expression of an inhibitor of cyclin-dependent kinases (CIP1/WAF1) in primary breast carcinomas with p53 mutations. Clin. Cancer Res., I: 907-912, 1995.
13. Zhuang, Z., Bertheau, P., Emmert-Buck, M. R., Liotta, L. A., Gnarra, J., Linehan, W. M., and Lubensky, I. A. A microdissection technique for archival DNA analysis of specific cell populations in lesions
14. Zhuang, Z., Merino, M. J., Chuaqui, R., Liotta, L. A., and Emmert-Buck, M. R. Identical allelic loss on chromosome 11q13 in microdissected in situ and invasive human breast cancer. Cancer Res., 55: 467-471, 1995.
15. Nayar, R., Zhuang, Z., Merino, M. J., and Silverberg, S. G. Loss of heterozygosity on chromosome 11q13 in lobular lesions of the breast using tissue microdissection and polymerase chain reaction. Hum. Pathol., 28: 277-282, 1997.
16. Radford, D. M., Fair, K. L., Phillips, N. J., Ritter, J. H., Steinbrueck, T., Holt, M. S., and Donis-Keller, H. Allelotyping of ductal carcinoma in situ of the breast: deletion of loci on 8p, 13q, 16q, 17p, and 17q. Cancer Res., 55: 3399-3405, 1995.
17. Chuaqui, R. F., Zhuang, Z., Emmert-Buck, M. R., Liotta, L. A., and Merino, M. J. Analysis of loss of heterozygosity on chromosome 11q13 in atypical ductal hyperplasia and in situ carcinoma of the breast. Am. J. Pathol., 150: 297-303, 1997.
18. Fujii, H., Szumel, R., Marsh, C., Zhou, W., and Gabrielson, E. Genetic progression, histological grade, and allelic loss in ductal carcinoma in situ of the breast. Cancer Res., 56: 5260-5265, 1996.
19. Lohmann, D., Ruhri, C., Schmitt, M., Graeff, H., and Höfler, H. Accumulation of p53 protein as an indicator for p53 gene mutation in breast cancer. Occurrence of false-positives and false-negatives. Diagn. Mol. Pathol., 2: 36-41, 1993.
20. Visscher, D. W., Sarkar, F. H., Shimoyama, R. K., and Crissman, J. D. Correlation between p53 immunostaining patterns and gene sequence mutations in breast carcinoma. Diagn. Mol. Pathol., 5: 187-193, 1996.
21. Chen, T., Dhingra, K., Sahin, A., Sneige, N., Hortobagyi, G., and Aldaz, C. M. Technical approach for the study of the genetic evolution of breast cancer from paraffin-embedded tissue sections. Breast Cancer Res. Treat., 39: 177-185, 1996.
22. Deng, G., Chen, L-C., Schott, D. R., Thor, A., Bhargava, V., Ljung, B-M., Chew, K., and Smith, H. S. Loss of heterozygosity and p53 gene mutations in breast cancer. Cancer Res., 54: 499-505, 1994.
23. O'Malley, F. P., Vnencak-Jones, C. L., Dupont, W. D., Pari, F., Manning, S., and Page, D. L. p53 mutations are confined to the comedo type ductal carcinoma in situ of the breast. Immunohistochemical and sequencing data. Lab. Invest., 71: 67-72, 1994.
24. Davidoff, A. M., Kerns, B-J. M., Pence, J. C., Marks, J. R., and Iglehart, J. D. p53 alterations in all stages of breast cancer. J. Surg. Oncol., 48: 260-267, 1991.