A HRM-based screening method detects RAD51C germ-line deleterious mutations in Spanish breast and ovarian cancer families

Breast Cancer Research and Treatment

Volumn 129, Issue 3, 2011, Pages 939-946

  Romero, Atocha ^a   Pérez Segura, Pedro ^a   Tosar, Alicia ^a   García Saenz, José Ángel ^a   Díaz Rubio, Eduardo ^a   Caldés, Trinidad ^a   De La Hoya, Miguel ^a  

^a HOSPITAL CLÍNICO SAN CARLOS   (Spain)

Author keywords

Germ line mutation; Hereditary breast and ovarian cancer; HRM; RAD51C

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ARTICLE; BREAST CANCER; CANCER SCREENING; CONTROLLED STUDY; ETHNICITY; FAMILY HISTORY; FEMALE; GENE DELETION; GENE FREQUENCY; GENE IDENTIFICATION; GENE INSERTION; GENE MUTATION; GENE SEQUENCE; GENOTYPE; GERM LINE MUTATION; HIGH RESOLUTION MELTING ANALYSIS; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; OVARY CANCER; PHENOTYPE; PRIORITY JOURNAL; RAD51C GENE; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; SPANISH; TUMOR GENE;

ADULT; BREAST NEOPLASMS; DNA-BINDING PROTEINS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; MALE; MIDDLE AGED; OVARIAN NEOPLASMS; PEDIGREE; SEQUENCE ANALYSIS, DNA; SPAIN;

EID: 80052583878     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-011-1543-x     Document Type: Article

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