Biosynthetic origin and mechanism of formation of the aminoribosyl moiety of peptidyl nucleoside antibiotics

Journal of the American Chemical Society

Volumn 133, Issue 36, 2011, Pages 14452-14459

  Chi, Xiuling ^a   Pahari, Pallab ^a   Nonaka, Koichi ^b   Van Lanen, Steven G ^a  

^a University of Kentucky   (United States)

^b Biopharmaceutical Research Group i   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOTRANSFERASE; BIOSYNTHETIC PATHWAY; CELL WALL BIOSYNTHESIS; DEOXYURIDINE; IN-VITRO; L-METHIONINE; MECHANISM OF FORMATION; MONOPHOSPHATES; NATURAL PRODUCTS; PEPTIDOGLYCANS; RIBOSYLATION; TRANSLOCASES; URIDYLYLTRANSFERASE;

ALDEHYDES; AMINO ACIDS; ANTIBIOTICS; BIOCHEMISTRY; BIOMOLECULES; BIOSYNTHESIS; ORGANIC COMPOUNDS; PHOSPHORYLATION;

SUGARS;

5 AMINO 5 DEOXYRIBOSYLTRANSFERASE; 5' AMINO 5 DEOXY ALPHA DEXTRO RIBOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; 5' AMINO 5' DEOXYURIDINE PHOSPHORYLASE; AMINOTRANSFERASE; ANTIBIOTIC AGENT; HEXOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; METHIONINE; PEPTIDYL NUCLEOSIDE ANTIBIOTIC; PHOSPHORYLASE; TRANSFERASE; UNCLASSIFIED DRUG; URIDINE 5' ALDEHYDE AMINOTRANSFERASE; URIDINE PHOSPHATE;

ARTICLE; BIOSYNTHESIS; CATALYSIS; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME KINETICS; GENE CLUSTER; GENE EXPRESSION; GLYCOSYLATION; IN VITRO STUDY; PH;

ANTI-BACTERIAL AGENTS; BIOLOGICAL AGENTS; GLYCOSYLATION; NUCLEOSIDES; NUCLEOTIDYLTRANSFERASES; PENTOSYLTRANSFERASES; TRANSAMINASES;

EID: 80052555950     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja206304k     Document Type: Article

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