Glandular gene expression of sinus mucosa in chronic rhinosinusitis with and without cystic fibrosis

American Journal of Respiratory Cell and Molecular Biology

Volumn 45, Issue 3, 2011, Pages 525-533

  Wu, Xiaofang ^a   Peters Hall, Jennifer R ^a,b   Ghimbovschi, Svetlana ^a   Mimms, Remy ^a   Rose, Mary C ^a,b   Penã, Maria T ^a,b  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Chronic rhinosinusitis; Cystic fibrosis; Hyperplasia; Microarrays; Submucosal glands

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR OTX2;

ADOLESCENT; ADULT; ARTICLE; CASE REPORT; CHILD; CHRONIC DISEASE; CONTROLLED STUDY; CYSTIC FIBROSIS; DSG3 GENE; FEMALE; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERPLASIA; IMMUNOFLUORESCENCE; KRT14 GENE; MALE; MICROARRAY ANALYSIS; MUCOSA INFLAMMATION; MYOEPITHELIUM CELL; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PTHLH GENE; RHINOSINUSITIS; SCHOOL CHILD; SUBMUCOSA; UPREGULATION;

ADOLESCENT; ADULT; CHILD; CHRONIC DISEASE; CYSTIC FIBROSIS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; HYPERPLASIA; MALE; NASAL MUCOSA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARANASAL SINUSES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHINITIS; SINUSITIS;

EID: 80052543336     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2010-0133OC     Document Type: Article

References (44)

1. Ordonez C.L., Khashayar R., Wong H.H., Ferrando R., Wu R., Hyde D.M., Hotchkiss J.A., Zhang Y., Novikov A., Dolganov G., et al. Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression. Am J Respir Crit Care Med 2001;163:517-523. (Pubitemid 32158539)
2. Rogers D.F. Mucus hypersecretion in chronic obstructive pulmonary diseases. Novartis Found Symp 2001;234:65-77.
3. Tos M., Mogensen C. Mucus production in chronic maxillary sinusitis: A quantitative histopathological study. Acta Otolaryngol 1984;97:151-159. (Pubitemid 14215107)
4. Pena M.T., Aujla P.K., Patel K.M., Zalzal G.H., Rose M.C. Immunohistochemical analyses of MUC5AC mucin expression in sinus mucosa of children with sinusitis and controls. Ann Otol Rhinol Laryngol 2005;114:958-965. (Pubitemid 43030940)
5. Pena M.T., Aujla P.K., Zudaire E., Watson A.M., Zalzal G.H., Rose M.C. Localization and expression of MUC5B and MUC7 mucins in pediatric sinus mucosa. Ann Otol Rhinol Laryngol 2007;116:389-397. (Pubitemid 46789681)
6. Hogg J.C., Timens W. The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol 2009;4:435-459.
7. Wu X., Amorn M., Aujla P.K., Rice S., Mimms R., Watson A.M., Peters-Hall J.R., Rose M.C., Peña MT. Histology and mucin immunohistochemistry of cystic fibrosis sinus mucosa. Archives Otolaryngology (In press)
8. Thurlbeck W.M., Benjamin B., Reid L. Development and distribution of mucous glands in the foetal human trachea. Br J Dis Chest 1961;55:54-64.
9. Bucher U., Reid L. Development of the mucus-secreting elements in human lung. Thorax 1961;16:219-225.
10. Borthwick D.W., Shahbazian M., Krantz Q.T., Dorin J.R., Randell S.H. Evidence for stem-cell niches in the tracheal epithelium. Am J Respir Cell Mol Biol 2001;24:662-670. (Pubitemid 32550587)
11. Liu X., Driskell R.R., Engelhardt J.F. Airway glandular development and stem cells. Curr Top Dev Biol 2004;64:33-56. (Pubitemid 39752392)
12. Driskell R.R., Goodheart M., Neff T., Liu X., Luo M., Moothart C., Sigmund C.D., Hosokawa R., Chai Y., Engelhardt J.F. Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis. Dev Biol 2007;305:90-102. (Pubitemid 46589407)
13. Duan D., Yue Y., Zhou W., Labed B., Ritchie T.C., Grosschedl R., Engelhardt J.F. Submucosal gland development in the airway is controlled by lymphoid enhancer binding factor 1 (LEF1). Development 1999;126:4441-4453.
14. Driskell R.R., Liu X., Luo M., Filali M., Zhou W., Abbott D., Cheng N., Moothart C., Sigmund C.D., Engelhardt J.F. Wnt-responsive element controls Lef-1 promoter expression during submucosal gland morphogenesis. Am J Physiol Lung Cell Mol Physiol 2004;287:L752-L763. (Pubitemid 39249388)
15. Rawlins E.L., Hogan B.L. Intercellular growth factor signaling and the development of mouse tracheal submucosal glands. Dev Dyn 2005;233:1378-1387.
16. Wills-Karp M., Luyimbazi J., Xu X., Schofield B., Neben T.Y., Karp C.L., Donaldson D.D. Interleukin-13: Central mediator of allergic asthma. Science 1998;282:2258-2261. (Pubitemid 29004074)
17. Grunig G., Warnock M., Wakil A.E., Venkayya R., Brombacher F., Rennick D.M., Sheppard D., Mohrs M., Donaldson D.D., Locksley R.M. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 1998;282:2261-2263. (Pubitemid 29004075)
18. Wu X., Ghimbovschi S., Aujla P.K., Patel K.C., Rose M.C., Pena M.T. Expression profiling of inflammatory mediators in pediatric sinus mucosa. Arch Otolaryngol Head Neck Surg 2009;135:65-72.
19. Almon R.R., DuBois D.C., Yao Z., Hoffman E.P., Ghimbovschi S., Jusko W.J. Microarray analysis of the temporal response of skeletal muscle to methylprednisolone: Comparative analysis of two dosing regimens. Physiol Genomics 2007;30:282-299. (Pubitemid 47296188)
20. Seo J., Gordish-Dressman H., Hoffman E.P. An interactive power analysis tool for microarray hypothesis testing and generation. Bioinformatics 2006;22:808-814.
21. Hong P., Wong W.H. GeneNotes: A novel information management software for biologists. BMC Bioinformatics 2005;6:20.
22. Sharma P., Dudus L., Nielsen P.A., Clausen H., Yankaskas J.R., Hollingsworth M.A., Engelhardt J.F. MUC5B and MUC7 are differentially expressed in mucous and serous cells of submucosal glands in human bronchial airways. Am J Respir Cell Mol Biol 1998;19:30-37. (Pubitemid 128354939)
23. Basbaum C., Finkbeiner W. Mucus-producing cells of the airways. In: Massaro D, editor. Lung cell biology. New York: Marcel Dekker; 1989. pp. 37-80.
24. Gugliotta P., Sapino A., Macri L., Skalli O., Gabbiani G., Bussolati G. Specific demonstration of myoepithelial cells by anti-alpha smooth muscle actin antibody. J Histochem Cytochem 1988;36:659-663.
25. Caldelari R., De Bruin A., Baumann D., Suter M.M., Bierkamp C., Balmer V., Mu? ller E. A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris. J Cell Biol 2001;153:823-834. (Pubitemid 34286113)
26. Merritt A.J., Berika M.Y., Zhai W., Kirk S.E., Ji B., Hardman M.J., Garrod D.R. Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation. Mol Cell Biol 2002;22:5846-5858. (Pubitemid 34815833)
27. Rose M.C., Voynow J.A. Respiratory tract mucin genes and mucin glycoproteins in health and disease. Physiol Rev 2006;86:245-278.
28. Basbaum C.B., Jany B., Finkbeiner W.E. The serous cell. Annu Rev Physiol 1990;52:97-113. (Pubitemid 20103529)
29. Evans M.J., Shami S.G., Cabral-Anderson L.J., Dekker N.P. Role of nonciliated cells in renewal of the bronchial epithelium of rats exposed to NO2. Am J Pathol 1986;123:126-133. (Pubitemid 16038141)
30. Runswick S.K., O'Hare M.J., Jones L., Streuli C.H., Garrod D.R. Desmosomal adhesion regulates epithelial morphogenesis and cell positioning. Nat Cell Biol 2001;3:823-830. (Pubitemid 32842688)
31. Coulombe P.A., Kopan R., Fuchs E. Expression of keratin K14 in the epidermis and hair follicle: Insights into complex programs of differentiation. J Cell Biol 1989;109:2295-2312. (Pubitemid 19282617)
32. Schermer A.S., Glavin S., Sun T.T. Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol 1986;103:49-62.
33. Ogawa Y., Toyosawa S., Ishida T., Ijuhin N. Keratin 14 immunoreactive cells in pleomorphic adenomas and adenoid cystic carcinomas of salivary glands. Virchows Arch 2000;437:58-68. (Pubitemid 30446917)
34. Evans M.J., Van Winkle L.S., Fanucchi M.V., Plopper C.G. Cellular and molecular characteristics of basal cells in airway epithelium. Exp Lung Res 2001;27:401-415. (Pubitemid 32641827)
35. Boers J.E., Ambergen A.W., Thunnissen F.B. Number and proliferation of basal and parabasal cells in normal human airway epithelium. Am J Respir Crit Care Med 1998;157:2000-2006.
36. Zabel M., Murawski M., Surdyk-Zasada J., Salwa-Zurawska W., Radziemski A. Immunocytochemical localisation of PTHrP (parathormone-related peptide) in myoepithelial cells of human sweat and parotid glands. Folia Histochem Cytobiol 1999;37:167-172. (Pubitemid 29339565)
37. Dunbar M.E., Wysolmerski J.J. Parathyroid hormone-related protein: A developmental regulatory molecule necessary for mammary gland development. J Mammary Gland Biol Neoplasia 1999;4:21-34.
38. Gammill L.S., Sive H. Identification of OTX2 target genes and restrictions in ectodermal competence during Xenopus cement gland formation. Development 1997;124:471-481. (Pubitemid 27101681)
39. Smythe W.R., Bridges N.D., Gaynor J.W., Nicolson S., Clark B.J., Spray T.L. Bilateral sequential lung transplant for ectodermal dysplasia. Ann Thorac Surg 2000;70:654-656.
40. Hogan B.L. Morphogenesis. Cell 1999;96:225-233. (Pubitemid 29059352)
41. Jaskoll T., Zhou Y.M., Chai Y., Makarenkova H.P., Collinson J.M., West J.D., Hajihosseini M.K., Lee J., Melnick M. Embryonic submandibular gland morphogenesis: Stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice. Cells Tissues Organs 2002;170:83-98. (Pubitemid 33151582)
42. Kulessa H., Turk G., Hogan B.L. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. EMBO J 2000;19:6664-6674. (Pubitemid 32011659)
43. Makarenkova H.P., Ito M., Govindarajan V., Faber S.C., Sun L., McMahon G., Overbeek P.A., Lang R.A. FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development. Development 2000;127:2563-2572. (Pubitemid 30426804)
44. Wu X., Peters-Hall J., Bose S., Pena M.T., Rose M.C. Human bronchial epithelial cells differentiate to 3D glandular acini on basement membrane matrix. Am J Respir Cell Mol Biol 2010; Aug 19. [Epub ahead of print] PMID: 20724555.