Development of an adenovirus vector lacking the expression of virus-associated RNAs

Journal of Controlled Release

Volumn 154, Issue 3, 2011, Pages 285-289

  MacHitani, Mitsuhiro ^a   Katayama, Kazufumi ^a   Sakurai, Fuminori ^a   Matsui, Hayato ^a   Yamaguchi, Tomoko ^b   Suzuki, Takayuki ^b   Miyoshi, Hiroyuki ^c   Kawabata, Kenji ^a,b   Mizuguchi, Hiroyuki ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^c Subteam for Manipulation of Cell Fate   (Japan)

Author keywords

Adenovirus vector; Gene therapy; Innate immunity; VA RNA

Indexed keywords

ADENOVIRUS VECTOR; CULTURED CELL; CYTOKINE PRODUCTION; GENOME ENCODES; HEK-293; HEK293 CELLS; INNATE IMMUNE RESPONSE; INNATE IMMUNITY; RNA POLYMERASE III; SMALL RNA; TISSUE DAMAGE; TRANSCRIPTIONAL CONTROL; TRANSDUCTION EFFICIENCY; TRANSFORMANTS; VA-RNA;

ENZYME ACTIVITY; GENE THERAPY; GENETIC ENGINEERING; IMMUNOLOGY; RNA; TISSUE; VIRUSES;

VECTORS;

ADENOVIRUS VECTOR; DNA DIRECTED RNA POLYMERASE III; GREEN FLUORESCENT PROTEIN; UNCLASSIFIED DRUG; UNTRANSLATED RNA; VIRUS ASSOCIATED RNA DELETED ADENOVIRUS VECTOR; VIRUS ASSOCIATED RNA I; VIRUS ASSOCIATED RNA II;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SAFETY; VIRUS GENOME;

ADENOVIRIDAE; CELL LINE; GENE DELETION; GENE EXPRESSION REGULATION, VIRAL; GENETIC VECTORS; HUMANS; RNA, VIRAL;

EID: 80052519700     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.06.020     Document Type: Article

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