메뉴 건너뛰기




Volumn 366, Issue 1579, 2011, Pages 2782-2789

Tuberculosis vaccines: Beyond bacilli Calmette-Guérin

Author keywords

Bacille Calmette Gu rin; Clinical trials; Efficacy; Immune correlates; Tuberculosis; Vaccine

Indexed keywords

BACTERIUM; CAUSE OF DEATH; DISEASE TREATMENT; DRUG DEVELOPMENT; EPIDEMIC; IMMUNE RESPONSE; IMMUNITY; INFECTIOUS DISEASE; RECOMBINATION; TUBERCULOSIS; VACCINATION; VACCINE;

EID: 80052515865     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2011.0097     Document Type: Review
Times cited : (111)

References (66)
  • 1
    • 77951088427 scopus 로고    scopus 로고
    • World Health Organization, Geneva, Switzerland: WHO Press
    • World Health Organization 2010 Global tuberculosis control. Geneva, Switzerland: WHO Press.
    • (2010) Global Tuberculosis Control
  • 2
    • 85020782149 scopus 로고    scopus 로고
    • World Health Organization, See
    • World Health Organization 2011 The global plan to stopTB 2011-2015. See http://www.stoptb.org/assets/documents/global/plan/TB_GlobalPlanToStopTB2011-2015.pdf.
    • (2011) The Global Plan to StopTB 2011-2015
  • 3
    • 0027751819 scopus 로고
    • Protective effect of BCG against tuberculous meningitis and miliary tuberculosis: A meta-analysis
    • doi:10.1093/ije/22.6.1154
    • Rodrigues, L. C., Diwan, V. K. & Wheeler, J.G. 1993 Protective effect of BCG against tuberculous meningitis and miliary tuberculosis: a meta-analysis. Int. J. Epidemiol. 22, 1154-1158. (doi:10.1093/ije/22.6.1154)
    • (1993) Int. J. Epidemiol , vol.22 , pp. 1154-1158
    • Rodrigues, L.C.1    Diwan, V.K.2    Wheeler, J.G.3
  • 4
    • 0031939337 scopus 로고    scopus 로고
    • Does the efficacy of BCG decline with time since vaccination
    • Sterne, J. A., Rodrigues, L. C. & Guedes, I. N. 1998 Does the efficacy of BCG decline with time since vaccination? Int. J. Tuberc. Lung Dis. 2, 200-207.
    • (1998) Int. J. Tuberc. Lung Dis , vol.2 , pp. 200-207
    • Sterne, J.A.1    Rodrigues, L.C.2    Guedes, I.N.3
  • 5
    • 33645989166 scopus 로고    scopus 로고
    • Effect of BCG vaccination on childhood tuberculous meningitis and miliary tuberculosis worldwide: A meta-analysis and assessment of cost-effectiveness
    • doi:10.1016/S0140-6736(06)68507-3
    • Trunz, B. B., Fine, P. & Dye, C. 2006 Effect of BCG vaccination on childhood tuberculous meningitis and miliary tuberculosis worldwide: a meta-analysis and assessment of cost-effectiveness. Lancet 367, 1173-1180. (doi:10.1016/S0140-6736(06)68507-3)
    • (2006) Lancet , vol.367 , pp. 1173-1180
    • Trunz, B.B.1    Fine, P.2    Dye, C.3
  • 6
    • 0019411265 scopus 로고
    • BCG vaccination of children against leprosy in Uganda: Final results
    • doi:10.1017/S002217240006945X
    • Stanley, S. J., Howland, C., Stone, M. M. & Sutherland, I. 1981 BCG vaccination of children against leprosy in Uganda: final results. J. Hyg (Lond). 87, 233-248. (doi:10.1017/S002217240006945X)
    • (1981) J. Hyg (Lond) , vol.87 , pp. 233-248
    • Stanley, S.J.1    Howland, C.2    Stone, M.M.3    Sutherland, I.4
  • 7
    • 0028153628 scopus 로고
    • Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature
    • doi:10.1001/jama.271.9.698
    • Colditz, G. A., Brewer, T. F., Berkey, C. S., Wilson, M. E., Burdick, E., Fineberg, H. V. & Mosteller, F. 1994 Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature. JAMA 271, 698-702. (doi:10.1001/jama.271.9.698)
    • (1994) JAMA , vol.271 , pp. 698-702
    • Colditz, G.A.1    Brewer, T.F.2    Berkey, C.S.3    Wilson, M.E.4    Burdick, E.5    Fineberg, H.V.6    Mosteller, F.7
  • 8
    • 26244458713 scopus 로고    scopus 로고
    • Effect of BCG revaccination on incidence of tuberculosis in school-aged children in Brazil: The BCG-REVAC cluster-randomised trial
    • doi:10.1016/S0140-6736 (05)67145-0
    • Rodrigues, L. C. et al. 2005 Effect of BCG revaccination on incidence of tuberculosis in school-aged children in Brazil: the BCG-REVAC cluster-randomised trial. Lancet 366, 1290-1295. (doi:10.1016/S0140-6736 (05)67145-0)
    • (2005) Lancet , vol.366 , pp. 1290-1295
    • Rodrigues, L.C.1
  • 9
    • 0035064072 scopus 로고    scopus 로고
    • Immunology of tuberculosis
    • doi:10.1146/ annurev.immunol.19.1.93
    • Flynn, J. L. & Chan, J. 2001 Immunology of tuberculosis. Annu. Rev. Immunol. 19, 93-129. (doi:10.1146/ annurev.immunol.19.1.93)
    • (2001) Annu Rev. Immunol , vol.19 , pp. 93-129
    • Flynn, J.L.1    Chan, J.2
  • 10
    • 0033136317 scopus 로고    scopus 로고
    • Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis
    • Caruso, A. M., Serbina, N., Klein, E., Triebold, K., Bloom, B. R. & Flynn, J. L. 1999 Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis. J. Immunol. 162, 5407-5416.
    • (1999) J. Immunol , vol.162 , pp. 5407-5416
    • Caruso, A.M.1    Serbina, N.2    Klein, E.3    Triebold, K.4    Bloom, B.R.5    Flynn, J.L.6
  • 11
    • 0027360333 scopus 로고
    • An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
    • doi:10.1084/jem.178.6.2249
    • Flynn, J. L., Chan, J., Triebold, K. J., Dalton, D. K., Stewart, T. A. & Bloom, B. R. 1993 An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178, 2249-2254. (doi:10.1084/jem.178.6.2249)
    • (1993) J. Exp. Med , vol.178 , pp. 2249-2254
    • Flynn, J.L.1    Chan, J.2    Triebold, K.J.3    Dalton, D.K.4    Stewart, T.A.5    Bloom, B.R.6
  • 12
    • 0030467174 scopus 로고    scopus 로고
    • A mutation in the interferon-gamma-receptor gene and susceptibility tomycobacterial infection
    • doi:10.1056/NEJM199612263352602
    • Newport, M. J., Huxley, C. M., Huston, S., Hawrylowicz, C. M., Oostra, B. A., Williamson, R. & Levin, M. 1996 A mutation in the interferon-gamma-receptor gene and susceptibility tomycobacterial infection. N. Engl. J. Med. 335, 1941-1949. (doi:10.1056/NEJM199612263352602)
    • (1996) N. Engl. J. Med , vol.335 , pp. 1941-1949
    • Newport, M.J.1    Huxley, C.M.2    Huston, S.3    Hawrylowicz, C.M.4    Oostra, B.A.5    Williamson, R.6    Levin, M.7
  • 13
    • 0028979703 scopus 로고
    • Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice
    • doi:10.1016/1074-7613(95)90001-2
    • Flynn, J. L., Goldstein, M. M., Chan, J., Triebold, K. J., Pfeffer, K., Lowenstein, C. J., Schreiber, R., Mak, T. W. & Bloom, B. R. 1995 Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity 2, 561-572. (doi:10.1016/1074-7613(95)90001-2)
    • (1995) Immunity , vol.2 , pp. 561-572
    • Flynn, J.L.1    Goldstein, M.M.2    Chan, J.3    Triebold, K.J.4    Pfeffer, K.5    Lowenstein, C.J.6    Schreiber, R.7    Mak, T.W.8    Bloom, B.R.9
  • 14
    • 0037373957 scopus 로고    scopus 로고
    • Antitumour necrosis factor agents and tuberculosis risk: Mechanisms of action and clinical management
    • doi:10.1016/S1473-3099(03) 00545-0
    • Gardam, M. A., Keystone, E. C., Menzies, R., Manners, S., Skamene, E., Long, R. & Vinh, D. C. 2003 Antitumour necrosis factor agents and tuberculosis risk: mechanisms of action and clinical management. Lancet Infect. Dis. 3, 148-155. (doi:10.1016/S1473-3099(03) 00545-0)
    • (2003) Lancet Infect. Dis , vol.3 , pp. 148-155
    • Gardam, M.A.1    Keystone, E.C.2    Menzies, R.3    Manners, S.4    Skamene, E.5    Long, R.6    Vinh, D.C.7
  • 15
    • 2142730100 scopus 로고    scopus 로고
    • Central memory and effector memory T cell subsets: Function, generation, and maintenance
    • doi:10.1146/annurev.immunol. 22.012703.104702
    • Sallusto, F., Geginat, J. & Lanzavecchia, A. 2004 Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu. Rev. Immunol. 22, 745-763. (doi:10.1146/annurev.immunol. 22.012703.104702)
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 745-763
    • Sallusto, F.1    Geginat, J.2    Lanzavecchia, A.3
  • 16
    • 0034636150 scopus 로고    scopus 로고
    • Relative contributions of distinct MHC class Idependent cell populations in protection to tuberculosis infection in mice
    • doi:10.1073/pnas.97.8.4204
    • Sousa, A. O., Mazzaccaro, R. J., Russell, R. G., Lee, F. K., Turner, O. C., Hong, S., Luc, V. K. & Barry, R. B. 2000 Relative contributions of distinct MHC class Idependent cell populations in protection to tuberculosis infection in mice. Proc. Natl Acad. Sci. USA 97, 4204-4208. (doi:10.1073/pnas.97.8.4204)
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 4204-4208
    • Sousa, A.O.1    Mazzaccaro, R.J.2    Russell, R.G.3    Lee, F.K.4    Turner, O.C.5    Hong, S.6    Luc, V.K.7    Barry, R.B.8
  • 17
    • 0034529550 scopus 로고    scopus 로고
    • Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells
    • doi:10. 1002/1521-4141(200012)30:12,3689::AID-IMMU36 89.3.0.CO;2-4
    • van Pinxteren, L. A., Cassidy, J. P., Smedegaard, B. H., Agger, E. M. & Andersen, P. 2000 Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells. Eur. J. Immunol. 30, 3689-3698. (doi:10. 1002/1521-4141(200012)30:12,3689::AID-IMMU36 89.3.0.CO;2-4)
    • (2000) Eur. J. Immunol , vol.30 , pp. 3689-3698
    • van Pinxteren, L.A.1    Cassidy, J.P.2    Smedegaard, B.H.3    Agger, E.M.4    Andersen, P.5
  • 18
    • 34248562792 scopus 로고    scopus 로고
    • 4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
    • doi:10.1038/ni1449
    • 4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat. Immunol. 8, 369-377. (doi:10.1038/ni1449
    • (2007) Nat Immunol , vol.8 , pp. 369-377
    • Khader, S.A.1
  • 19
    • 0035949685 scopus 로고    scopus 로고
    • Divergent effect of bacillus Calmette-Guerin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: Implications for primate models in tuberculosis vaccine research
    • doi:10.1073/pnas.201404898
    • Langermans, J. A. et al. 2001 Divergent effect of bacillus Calmette-Guerin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: implications for primate models in tuberculosis vaccine research. Proc. Natl Acad. Sci. USA 98, 11 497-11 502. (doi:10.1073/pnas.201404898)
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 11497-11502
    • Langermans, J.A.1
  • 20
    • 34547624348 scopus 로고    scopus 로고
    • Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis
    • doi:10.1073/pnas.0703510104
    • Mittrucker, H. W., Steinhoff, U., Kohler, A., Krause, M., Lazar, D., Mex, P., Miekley, D. & Kaufmann, S. H. E. 2007 Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis. Proc. Natl Acad. Sci. USA 104, 12 434-12 439. (doi:10.1073/pnas.0703510104)
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 12434-12439
    • Mittrucker, H.W.1    Steinhoff, U.2    Kohler, A.3    Krause, M.4    Lazar, D.5    Mex, P.6    Miekley, D.7    Kaufmann, S.H.E.8
  • 21
    • 34250770421 scopus 로고    scopus 로고
    • Vaccination of cattle with Danish and Pasteur strains of Mycobacterium bovis BCG induce different levels of IFNgamma post-vaccination, but induce similar levels of protection against bovine tuberculosis
    • doi:10.1016/j.vetimm.2007.04.005
    • Wedlock, D. N., Denis, M., Vordermeier, H. M., Hewinson, R. G. & Buddle, B. M. 2007 Vaccination of cattle with Danish and Pasteur strains of Mycobacterium bovis BCG induce different levels of IFNgamma post-vaccination, but induce similar levels of protection against bovine tuberculosis. Vet. Immunol. Immunopathol. 118, 50-58. (doi:10.1016/j.vetimm.2007.04.005)
    • (2007) Vet. Immunol. Immunopathol , vol.118 , pp. 50-58
    • Wedlock, D.N.1    Denis, M.2    Vordermeier, H.M.3    Hewinson, R.G.4    Buddle, B.M.5
  • 22
    • 67651210877 scopus 로고    scopus 로고
    • Viral booster vaccines improve Mycobacterium bovis BCG-induced protection against bovine tuberculosis
    • doi:10.1128/IAI.00287-09
    • Vordermeier, H. M. et al. 2009 Viral booster vaccines improve Mycobacterium bovis BCG-induced protection against bovine tuberculosis. Infect. Immun. 77, 3364-3373. (doi:10.1128/IAI.00287-09)
    • (2009) Infect. Immun , vol.77 , pp. 3364-3373
    • Vordermeier, H.M.1
  • 23
    • 77958475885 scopus 로고    scopus 로고
    • Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis, following BCG vaccination of newborns
    • doi:10.1164/rccm.201003-0334OC
    • Kagina, B. M. et al. 2010 Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis, following BCG vaccination of newborns. Am. J. Respir. Crit. Care Med. 182, 1073-1079. (doi:10.1164/rccm.201003-0334OC)
    • (2010) Am. J. Respir. Crit. Care Med , vol.182 , pp. 1073-1079
    • Kagina, B.M.1
  • 24
    • 33845197461 scopus 로고    scopus 로고
    • The risk of disseminated Bacille Calmette-Guerin (BCG) disease in HIV-infected children
    • doi:10.1016/j.vaccine.2006.07.020
    • Hesseling, A. C., Marais, B. J., Gie, R. P., Schaaf, H. S., Fine, P. E., Godfrey-Faussett, P. & Beyers, N. 2007 The risk of disseminated Bacille Calmette-Guerin (BCG) disease in HIV-infected children. Vaccine 25, 14-18. (doi:10.1016/j.vaccine.2006.07.020)
    • (2007) Vaccine , vol.25 , pp. 14-18
    • Hesseling, A.C.1    Marais, B.J.2    Gie, R.P.3    Schaaf, H.S.4    Fine, P.E.5    Godfrey-Faussett, P.6    Beyers, N.7
  • 25
    • 54949108635 scopus 로고    scopus 로고
    • A new recombinant bacille Calmette-Guerin vaccine safely induces significantly enhanced tuberculosis-specific immunity in human volunteers
    • doi:10.1086/592450
    • Hoft, D. F. et al. 2008 A new recombinant bacille Calmette-Guerin vaccine safely induces significantly enhanced tuberculosis-specific immunity in human volunteers. J. Infect. Dis. 198, 1491-1501. (doi:10.1086/592450)
    • (2008) J. Infect. Dis , vol.198 , pp. 1491-1501
    • Hoft, D.F.1
  • 26
    • 22344433382 scopus 로고    scopus 로고
    • Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin
    • doi:10.1172/JCI24617
    • Grode, L. et al. 2005 Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin. J. Clin. Invest. 115, 2472-2479. (doi:10.1172/JCI24617)
    • (2005) J. Clin. Invest , vol.115 , pp. 2472-2479
    • Grode, L.1
  • 27
    • 67649321241 scopus 로고    scopus 로고
    • Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis
    • doi:10.1016/j.vaccine. 2009.05.048
    • Sun, R. et al. 2009 Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis. Vaccine 27, 4412-4423. (doi:10.1016/j.vaccine. 2009.05.048)
    • (2009) Vaccine , vol.27 , pp. 4412-4423
    • Sun, R.1
  • 28
    • 77949362006 scopus 로고    scopus 로고
    • Prevention of tuberculosis in bacille Calmette-Guerin-primed, HIV-infected adults boosted with an inactivated whole-cell mycobacterial vaccine
    • doi:10.1097/QAD. 0b013e3283350f1b
    • von Reyn, C. F. et al. 2010 Prevention of tuberculosis in bacille Calmette-Guerin-primed, HIV-infected adults boosted with an inactivated whole-cell mycobacterial vaccine. AIDS 24, 675-685. (doi:10.1097/QAD. 0b013e3283350f1b)
    • (2010) AIDS , vol.24 , pp. 675-685
    • von Reyn, C.F.1
  • 29
    • 70349551599 scopus 로고    scopus 로고
    • The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans
    • Von Eschen, K. et al. 2009 The candidate tuberculosis vaccine Mtb72F/AS02A: tolerability and immunogenicity in humans. Hum. Vaccin. 5, 475-482.
    • (2009) Hum. Vaccin , vol.5 , pp. 475-482
    • von Eschen, K.1
  • 30
    • 77950690752 scopus 로고    scopus 로고
    • Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naive human volunteers
    • doi:10.1016/j.vaccine. 2010.02.094
    • van Dissel, J. T. et al. 2010 Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naive human volunteers. Vaccine 28, 3571-3581. (doi:10.1016/j.vaccine. 2010.02.094)
    • (2010) Vaccine , vol.28 , pp. 3571-3581
    • van Dissel, J.T.1
  • 31
    • 18644373991 scopus 로고    scopus 로고
    • Exchanging ESAT6 with TB10.4 in an Ag85B fusion moleculebased tuberculosis subunit vaccine: Efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy
    • Dietrich, J., Aagaard, C., Leah, R., Olsen, A. W., Stryhn, A., Doherty, T. M. & Andersen, P. 2005 Exchanging ESAT6 with TB10.4 in an Ag85B fusion moleculebased tuberculosis subunit vaccine: efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy. J. Immunol. 174, 6332-6339.
    • (2005) J. Immunol , vol.174 , pp. 6332-6339
    • Dietrich, J.1    Aagaard, C.2    Leah, R.3    Olsen, A.W.4    Stryhn, A.5    Doherty, T.M.6    Andersen, P.7
  • 32
    • 77951826915 scopus 로고    scopus 로고
    • 8+ T cells in adults
    • doi:10.1164/rccm.200910-1484OC
    • 8+ T cells in adults. Am. J. Respir. Crit. Care Med. 181, 1407-1417. (doi:10.1164/rccm.200910-1484OC)
    • (2010) Am. J. Respir. Crit. Care Med , vol.181 , pp. 1407-1417
    • Abel, B.1
  • 34
    • 74249099784 scopus 로고    scopus 로고
    • Modified vaccinia Ankaraexpressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells
    • doi:10. 1002/eji.200939754
    • Scriba, T. J. et al. 2010 Modified vaccinia Ankaraexpressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells. Eur. J. Immunol. 40, 279-290. (doi:10. 1002/eji.200939754)
    • (2010) Eur. J. Immunol , vol.40 , pp. 279-290
    • Scriba, T.J.1
  • 35
    • 0034610299 scopus 로고    scopus 로고
    • Recombinant bacillus Calmette-Guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model
    • doi:10.1073/ pnas.250480397
    • Horwitz, M. A., Harth, G., Dillon, B. J. & Maslesa-Galic, S. 2000 Recombinant bacillus Calmette-Guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model. Proc. Natl Acad. Sci. USA 97, 13 853-13 858. (doi:10.1073/ pnas.250480397)
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 13853-13858
    • Horwitz, M.A.1    Harth, G.2    Dillon, B.J.3    Maslesa-Galic, S.4
  • 36
    • 33645314357 scopus 로고    scopus 로고
    • The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs
    • doi:10. 1016/j.vaccine.2006.03.017
    • Martin, C. et al. 2006 The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs. Vaccine 24, 3408-3419. (doi:10. 1016/j.vaccine.2006.03.017)
    • (2006) Vaccine , vol.24 , pp. 3408-3419
    • Martin, C.1
  • 37
    • 67649482280 scopus 로고    scopus 로고
    • Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates
    • doi:10.1016/j.vaccine.2009. 05.050
    • Larsen, M. H. et al. 2009 Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates. Vaccine 27, 4709-4717. (doi:10.1016/j.vaccine.2009. 05.050)
    • (2009) Vaccine , vol.27 , pp. 4709-4717
    • Larsen, M.H.1
  • 38
    • 77349109263 scopus 로고    scopus 로고
    • The second Geneva consensus: Recommendations for novel live TB vaccines
    • doi:10.1016/j.vaccine.2009.12.083
    • Walker, K. B. et al. 2010 The second Geneva consensus: recommendations for novel live TB vaccines. Vaccine 28, 2259-2270. (doi:10.1016/j.vaccine.2009.12.083)
    • (2010) Vaccine , vol.28 , pp. 2259-2270
    • Walker, K.B.1
  • 39
    • 21044444574 scopus 로고    scopus 로고
    • New live mycobacterial vaccines: The Geneva consensus on essential steps towards clinical development
    • doi:10. 1016/j.vaccine.2005.03.001
    • Kamath, A. T. et al. 2005 New live mycobacterial vaccines: the Geneva consensus on essential steps towards clinical development. Vaccine 23, 3753-3761. (doi:10. 1016/j.vaccine.2005.03.001)
    • (2005) Vaccine , vol.23 , pp. 3753-3761
    • Kamath, A.T.1
  • 40
    • 0025696575 scopus 로고
    • Mycobacterium vaccae in immunoprophylaxis and immunotherapy of leprosy and tuberculosis
    • doi:10.1016/0264-410X(90)90002-4
    • Stanford, J. L. et al. 1990 Mycobacterium vaccae in immunoprophylaxis and immunotherapy of leprosy and tuberculosis. Vaccine 8, 525-530. (doi:10.1016/0264-410X(90)90002-4)
    • (1990) Vaccine , vol.8 , pp. 525-530
    • Stanford, J.L.1
  • 41
    • 0033788630 scopus 로고    scopus 로고
    • Double-blind placebo-controlled trial of Mycobacterium vaccae immunotherapy for tuberculosis in KwaZulu, South Africa
    • 1991-97, doi:10.1016/S0035-9203(00)90088-9
    • Mayo, R. E. & Stanford, J. L. 2000 Double-blind placebo-controlled trial of Mycobacterium vaccae immunotherapy for tuberculosis in KwaZulu, South Africa, 1991-97. Trans. R. Soc. Trop. Med. Hyg. 94, 563-568. (doi:10.1016/S0035-9203(00)90088-9)
    • (2000) Trans. R. Soc. Trop. Med. Hyg , vol.94 , pp. 563-568
    • Mayo, R.E.1    Stanford, J.L.2
  • 42
    • 2942596008 scopus 로고    scopus 로고
    • Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein
    • Skeiky, Y. A. et al. 2004 Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein. J. Immunol. 172, 7618-7628.
    • (2004) J. Immunol , vol.172 , pp. 7618-7628
    • Skeiky, Y.A.1
  • 43
    • 78449242585 scopus 로고    scopus 로고
    • Evaluation of the safety and immunogenicity of two antigen concentrations of the Mtb72F/AS02(A) candidate tuberculosis vaccine in purified protein derivative-negative adults
    • doi:10.1128/CVI.00133-10
    • Leroux-Roels, I. et al. 2010 Evaluation of the safety and immunogenicity of two antigen concentrations of the Mtb72F/AS02(A) candidate tuberculosis vaccine in purified protein derivative-negative adults. Clin. Vaccine Immunol. 17, 1763-1771. (doi:10.1128/CVI.00133-10)
    • (2010) Clin. Vaccine Immunol , vol.17 , pp. 1763-1771
    • Leroux-Roels, I.1
  • 44
    • 33750319222 scopus 로고    scopus 로고
    • Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity
    • Dietrich, J., Andersen, C., Rappuoli, R., Doherty, T. M., Jensen, C. G. & Andersen, P. 2006 Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity. J. Immunol. 177, 6353-6360.
    • (2006) J. Immunol , vol.177 , pp. 6353-6360
    • Dietrich, J.1    Andersen, C.2    Rappuoli, R.3    Doherty, T.M.4    Jensen, C.G.5    Andersen, P.6
  • 45
    • 20144389346 scopus 로고    scopus 로고
    • Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis
    • doi:10.1016/j.tube.2004.09.009
    • Williams, A. et al. 2005 Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis. Tuberculosis (Edinb). 85, 29-38. (doi:10.1016/j.tube.2004.09.009)
    • (2005) Tuberculosis (Edinb) , vol.85 , pp. 29-38
    • Williams, A.1
  • 46
    • 9644266918 scopus 로고    scopus 로고
    • Interferongamma assays in the immunodiagnosis of tuberculosis: A systematic review
    • doi:10. 1016/S1473-3099(04)01206-X
    • Pai, M., Riley, L. W. & Colford Jr, J. M. 2004 Interferongamma assays in the immunodiagnosis of tuberculosis: a systematic review. Lancet Infect. Dis. 4, 761-776. (doi:10. 1016/S1473-3099(04)01206-X)
    • (2004) Lancet Infect. Dis , vol.4 , pp. 761-776
    • Pai, M.1    Riley, L.W.2    Colford, J.M.3
  • 48
    • 2942562284 scopus 로고    scopus 로고
    • Adenovirus types 5 and 35 seroprevalence in AIDS risk groups supports type 35 as a vaccine vector
    • doi:10.1097/ 00002030-200405210-00019
    • Kostense, S. et al. 2004 Adenovirus types 5 and 35 seroprevalence in AIDS risk groups supports type 35 as a vaccine vector. AIDS 18, 1213-1216. (doi:10.1097/ 00002030-200405210-00019)
    • (2004) AIDS , vol.18 , pp. 1213-1216
    • Kostense, S.1
  • 49
    • 34547634035 scopus 로고    scopus 로고
    • Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon
    • doi:10.1128/IAI.00004-07
    • Radosevic, K. et al. 2007 Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon. Infect. Immun. 75, 4105-4115. (doi:10.1128/IAI.00004-07)
    • (2007) Infect. Immun , vol.75 , pp. 4105-4115
    • Radosevic, K.1
  • 50
    • 56849108004 scopus 로고    scopus 로고
    • RBCG induces strong antigenspecific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector
    • Magalhaes, doi:10.1371/ journal.pone.0003790
    • Magalhaes, I. et al. 2008 rBCG induces strong antigenspecific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector. PLoS ONE 3, e3790. (doi:10.1371/ journal.pone.0003790)
    • PLoS ONE , vol.3
    • Magalhaes, I.1
  • 51
    • 0018246525 scopus 로고
    • The smallpox vaccination strain MVA: Marker, genetic structure, experience gained with the parenteral vaccination and behavior in organisms with a debilitated defence mechanism (author's Transl)
    • Mayr, A., Stickl, H., Muller, H. K., Danner, K. & Singer, H. 1978 The smallpox vaccination strain MVA: marker, genetic structure, experience gained with the parenteral vaccination and behavior in organisms with a debilitated defence mechanism (author's Transl). Zentralbl. Bakteriol B 167, 375-390.
    • (1978) Zentralbl. Bakteriol B , vol.167 , pp. 375-390
    • Mayr, A.1    Stickl, H.2    Muller, H.K.3    Danner, K.4    Singer, H.5
  • 52
    • 0042346025 scopus 로고    scopus 로고
    • Enhanced immunogenicity and protective efficacy against Mycobacterium tuberculosis of bacille Calmette-Guerin vaccine using mucosal administration and boosting with a recombinant modified vaccinia virus Ankara
    • Goonetilleke, N. P., McShane, H., Hannan, C. M., Anderson, R. J., Brookes, R. H. & Hill, A. V. 2003 Enhanced immunogenicity and protective efficacy against Mycobacterium tuberculosis of bacille Calmette-Guerin vaccine using mucosal administration and boosting with a recombinant modified vaccinia virus Ankara. J. Immunol. 171, 1602-1609.
    • (2003) J. Immunol , vol.171 , pp. 1602-1609
    • Goonetilleke, N.P.1    McShane, H.2    Hannan, C.M.3    Anderson, R.J.4    Brookes, R.H.5    Hill, A.V.6
  • 53
    • 19744367216 scopus 로고    scopus 로고
    • Boosting with poxviruses enhances Mycobacterium bovis BCG efficacy against tuberculosis in guinea pigs
    • doi:10.1128/IAI.73.6.3814-3816.2005
    • Williams, A., Goonetilleke, N. P., McShane, H., Clark, S. O., Hatch, G., Gilbert, S. C. & Hill, A. V. S. 2005 Boosting with poxviruses enhances Mycobacterium bovis BCG efficacy against tuberculosis in guinea pigs. Infect. Immun. 73, 3814-3816. (doi:10.1128/IAI.73.6.3814-3816.2005)
    • (2005) Infect. Immun , vol.73 , pp. 3814-3816
    • Williams, A.1    Goonetilleke, N.P.2    McShane, H.3    Clark, S.O.4    Hatch, G.5    Gilbert, S.C.6    Hill, A.V.S.7
  • 54
    • 65349186494 scopus 로고    scopus 로고
    • MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques
    • doi:10.1371/journal. pone.0005264
    • Verreck, F. A. et al. 2009 MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques. PLoS ONE 4, e5264. (doi:10.1371/journal. pone.0005264)
    • (2009) PLoS ONE , vol.e5264 , pp. 4
    • Verreck, F.A.1
  • 55
    • 0037686337 scopus 로고    scopus 로고
    • Development of vaccines to control bovine tuberculosis in cattle and relationship to vaccine development for other intracellular pathogens
    • doi:10.1016/S0020-7519(03) 00060-2
    • Buddle, B. M., Pollock, J. M., Skinner, M. A. & Wedlock, D. N. 2003 Development of vaccines to control bovine tuberculosis in cattle and relationship to vaccine development for other intracellular pathogens. Int. J. Parasitol. 33, 555-566. (doi:10.1016/S0020-7519(03) 00060-2)
    • (2003) Int. J. Parasitol , vol.33 , pp. 555-566
    • Buddle, B.M.1    Pollock, J.M.2    Skinner, M.A.3    Wedlock, D.N.4
  • 56
    • 0037103142 scopus 로고    scopus 로고
    • Evolution of epitope-specific memory CD4(+) T cells after clearance of hepatitis C virus
    • Godkin, A. J., Thomas, H. C. & Openshaw, P. J. 2002 Evolution of epitope-specific memory CD4(+) T cells after clearance of hepatitis C virus. J. Immunol. 169, 2210-2214.
    • (2002) J. Immunol , vol.169 , pp. 2210-2214
    • Godkin, A.J.1    Thomas, H.C.2    Openshaw, P.J.3
  • 57
    • 85014177704 scopus 로고
    • Forsetzung der Mitteilungen uber ein Heilmittel gegen Tuberkulose
    • doi:10.1055/s-0029-1206198
    • Koch, R. 1891 Forsetzung der Mitteilungen uber ein Heilmittel gegen Tuberkulose. Dtsch. Med. Wochenschr. 17, 101-102. (doi:10.1055/s-0029-1206198)
    • (1891) Dtsch. Med. Wochenschr , vol.17 , pp. 101-102
    • Koch, R.1
  • 58
    • 0037378872 scopus 로고    scopus 로고
    • Pulmonary necrosis resulting from DNA vaccination against tuberculosis
    • doi:10.1128/IAI.71.4. 2192-2198.2003
    • Taylor, J. L., Turner, O. C., Basaraba, R. J., Belisle, J. T., Huygen, K. & Orme, I. M. 2003 Pulmonary necrosis resulting from DNA vaccination against tuberculosis. Infect. Immun. 71, 2192-2198. (doi:10.1128/IAI.71.4. 2192-2198.2003)
    • (2003) Infect. Immun , vol.71 , pp. 2192-2198
    • Taylor, J.L.1    Turner, O.C.2    Basaraba, R.J.3    Belisle, J.T.4    Huygen, K.5    Orme, I.M.6
  • 59
    • 41849129820 scopus 로고    scopus 로고
    • Boosting BCG with recombinant modified vaccinia ankara expressing antigen 85A: Different boosting intervals and implications for efficacy trials
    • doi:10.1371/journal.pone. 0001052
    • Pathan, A. A. et al. 2007 Boosting BCG with recombinant modified vaccinia ankara expressing antigen 85A: different boosting intervals and implications for efficacy trials. PLoS ONE 2, e1052. (doi:10.1371/journal.pone. 0001052)
    • (2007) PLoS ONE , vol.e1052 , pp. 2
    • Pathan, A.A.1
  • 60
    • 67649980065 scopus 로고    scopus 로고
    • Safety and immunogenicity of boosting BCG vaccinated subjects with BCG: Comparison with boosting with a new TB vaccine, MVA85A
    • doi:10.1371/journal.pone. 0005934
    • Whelan, K. T., Pathan, A. A., Sander, C. R., Fletcher, H. A., Poulton, I., Alder, N. C., Hill, A. V. S., McShane, H. & Kallas, E. G. 2009 Safety and immunogenicity of boosting BCG vaccinated subjects with BCG: comparison with boosting with a new TB vaccine, MVA85A. PLoS ONE 4, e5934. (doi:10.1371/journal.pone. 0005934)
    • (2009) PLoS ONE , vol.e5934 , pp. 4
    • Whelan, K.T.1    Pathan, A.A.2    Sander, C.R.3    Fletcher, H.A.4    Poulton, I.5    Alder, N.C.6    Hill, A.V.S.7    McShane, H.8    Kallas, E.G.9
  • 61
    • 36248967655 scopus 로고    scopus 로고
    • 4+ memory T lymphocyte populations
    • doi:10.1002/eji.200737504
    • 4+ memory T lymphocyte populations. Eur. J. Immunol. 37, 3089-3100. (doi:10.1002/eji.200737504)
    • (2007) Eur. J. Immunol , vol.37 , pp. 3089-3100
    • Beveridge, N.E.1
  • 64
    • 48749107581 scopus 로고    scopus 로고
    • Safety and immunogenicity of a new tuberculosis vaccine, MVA85A
    • healthy adults in South Africa, doi:10. 1086/590185
    • Hawkridge, T. et al. 2008 Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa. J. Infect. Dis. 198, 544-552. (doi:10. 1086/590185)
    • (2008) J. Infect. Dis , vol.198 , pp. 544-552
    • Hawkridge, T.1
  • 65
    • 0012746992 scopus 로고    scopus 로고
    • The growing burden of tuberculosis: Global trends and interactions with the HIV epidemic
    • doi:10.1001/archinte.163.9.1009
    • Corbett, E. L., Watt, C. J., Walker, N., Maher, D., Williams, B. G., Raviglione, M. C. & Dye, C. 2003 The growing burden of tuberculosis: global trends and interactions with the HIV epidemic. Arch. Intern. Med. 163, 1009-1021. (doi:10.1001/archinte.163.9.1009)
    • (2003) Arch. Intern. Med , vol.163 , pp. 1009-1021
    • Corbett, E.L.1    Watt, C.J.2    Walker, N.3    Maher, D.4    Williams, B.G.5    Raviglione, M.C.6    Dye, C.7
  • 66
    • 57549113472 scopus 로고    scopus 로고
    • Efficacy of percutaneous versus intradermal BCG in the prevention of tuberculosis in South African infants: Randomised trial
    • doi:10.1136/bmj.a2052
    • Hawkridge, A. et al. 2008 Efficacy of percutaneous versus intradermal BCG in the prevention of tuberculosis in South African infants: randomised trial. Br. Med. J. 337, a2052. (doi:10.1136/bmj.a2052)
    • (2008) Br. Med. J , vol.a2052 , pp. 337
    • Hawkridge, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.