Preparation and optimization of doxorubicin-loaded albumin nanoparticles using response surface methodology

Drug Development and Industrial Pharmacy

Volumn 37, Issue 10, 2011, Pages 1170-1180

  Li, Lei ^a   Zhao, Xiuli ^a   Yang, Chunrong ^a,b   Hu, Haiyang ^a   Qiao, Mingxi ^a   Chen, Dawei ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b JIAMUSI UNIVERSITY   (China)

Author keywords

Albumin nanoparticles; Central composite design; Desolvation; Doxorubicin; Optimization; Response surface methodology

Indexed keywords

ALBUMIN NANOPARTICLE; DOXORUBICIN; GLUTARALDEHYDE; NANOPARTICLE; UNCLASSIFIED DRUG;

ARTICLE; CENTRAL COMPOSITE DESIGN; CONCENTRATION (PARAMETERS); DESOLVATION TECHNIQUE; DRUG RELEASE; DRUG STABILITY; DRUG STORAGE; EXPERIMENTAL DESIGN; NANOENCAPSULATION; NANOFABRICATION; PARTICLE SIZE; PH; PROCESS OPTIMIZATION; RESPONSE SURFACE METHOD; ZETA POTENTIAL;

ALBUMINS; ANTIBIOTICS, ANTINEOPLASTIC; DOXORUBICIN; DRUG CARRIERS; DRUG COMPOUNDING; HUMANS; NANOPARTICLES; NEOPLASMS; PARTICLE SIZE; SOLUBILITY; SURFACE PROPERTIES;

EID: 80052483592     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2011.563781     Document Type: Article

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