Calpastatin is associated with lymphovascular invasion in breast cancer

Breast

Volumn 20, Issue 5, 2011, Pages 413-418

  Storr, Sarah J ^a   Mohammed, Rabab A A ^a,d   Woolston, Caroline M ^a   Green, Andrew R ^a   Parr, Tim ^a   Spiteri, Inmaculada ^b   Caldas, Carlos ^b   Ball, Graham R ^c   Ellis, Ian O ^a   Martin, Stewart G ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

^c NOTTINGHAM TRENT UNIVERSITY   (United Kingdom)

^d Assiut University   (Egypt)

Author keywords

Breast cancer; Calpain; Calpastatin; Lymphovascular invasion; Metastasis

Indexed keywords

CALPASTATIN; MESSENGER RNA;

ADULT; AGED; ARTICLE; ARTIFICIAL NEURAL NETWORK; BREAST CANCER; CANCER PATIENT; CONTROLLED STUDY; ERROR; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH VESSEL; MAJOR CLINICAL STUDY; METASTASIS; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION;

EID: 80052472563     PISSN: 09609776     EISSN: 15323080     Source Type: Journal    
DOI: 10.1016/j.breast.2011.04.002     Document Type: Article

References (40)

1. Mohammed R.A.A., Martin S.G., Gill M.S., Green A.R., Paish E.C., Ellis I.O. Improved methods for detecting lymphovascular invasion demonstrate it that is the predominant method of vascular invasion in breast cancer and has important clinical consequences. Am J Surg Pathol 2007, 31:1825-1833.
2. Pepper M.S., Tille J.C., Nisato R., Skobe M. Lymphangiogenesis and tumour metastasis. Cell Tissue Res 2003, 314:167-177.
3. Irjala H., Alanen K., Grénman R., Heikkilä P., Joensuu H., Jalkanen S. Mannose receptor (MR) and common lymphatic endothelial and vascular endothelial receptor (CLEVER)-1 direct the binding of cancer cells to the lymph vessel endothelium. Cancer Res 2003, 63:4671-4676.
4. Issa A., Le T.X., Shoushtari A.N., Shields J.D., Swartz M.A. Vascular endothelial growth factor-C and C-C chemokine receptor-7 in tumour cell-lymphatic cross-talk promote invasive phenotype. Cancer Res 2009, 69:349-357.
5. St.Croix B., Rago C., Velculescu V., Traverso G., Romans K.E., Montgomery E., et al. Genes expressed in human tumour endothelium. Science 2000, 289:1197-1202.
6. Clasper S., Royston D., Baban D., Cao Y., Ewers S., Butz S., et al. A novel gene expression profile in lymphatics associated with tumour growth and nodal metastasis. Cancer Res 2008, 68:7293-7303.
7. Dicken B.J., Graham K., Hamilton S.M., Andrews S., Lai R., Listgarten J., et al. Lymphovascular invasion is associated with poor survival in gastric cancer. Ann Surg 2006, 243:64-73.
8. Zhang X.-H., Huang D.-P., Guo G.-L., Chen G.-R., Zhang H.-X., Wan L., et al. Coexpression of VEGF-C and COX-2 and its association with lymphangiogenesis in human breast cancer. BMC Cancer 2008, 8:4.
9. Neri A., Marrelli D., Roviello F., De Marco G., Mariani F., De Stefano A., et al. Bcl-2 expression correlates with lymphovascular invasion and long-term prognosis in breast cancer. Breast Cancer Res Treat 2006, 99:77-83.
10. Lu X., Lu X., Wang Z.C., Iglehart J.D., Zhang X., Richardson A.L. Predicting clinical features of breast cancer with gene expression patters. Breast Cancer Res Treat 2008, 108:191-201.
11. Abd El-Rehim D.M., Ball G., Pinder S.E., Rakha E., Paish C., Robertson J.F., et al. High throughput protein expression analysis using tissue microarray technology of a large well characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses. Int J Cancer 2005, 116:340-350.
12. Rakha E.A., Abd El-Rehim D., Paish C., Green A.R., Lee A.H., Robertson J.F., et al. Basal phenotype identifies a poor prognostic subgroup of breast cancer of clinical importance. Eur J Cancer 2006, 42:3149-3156.
13. McShane L.M., Altman D.G., Sauerbrei W., Taube S.E., Gion M., Clark G.M. Reporting recommendations for tumour marker prognostic studies (REMARK). Breast Cancer Res Treat 2006, 100:229-235.
14. Chin S.F., Teschendorff A.E., Marioni J.C., Wang Y., Barbosa-Morais N.L., Thorne N.P., et al. High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer. Genome Biol 2007, 8:R215.
15. Blenkiron C., Goldstein L.D., Thorne N.P., Spiteri I., Chen S.-F., Dunning M.J., et al. MicroRNA expression profiling of human breast cancer identifies new markers of tumour subtype. Genome Biol 2007, 8:R214.
16. Naderi A., Teschendorff A.E., Barbosa-Morais N.L., Pinder S.E., Green A.R., Powe D.G., et al. A gene expression signature to predict survival in breast cancer across independent data sets. Oncogene 2007, 26:1507-1516.
17. Ball G., Mian S., Holding F., Allibone R.O., Lowe J., Ali S., et al. An integrated approach utilising artificial neural networks and SELDI mass spectrometry for the classification of human tumours and rapid identification of potential biomarkers. Bioinformatics 2002, 18:395-404.
18. Lancashire L.J., Powe D.G., Reis-Filho J.S., Rakha E., Lemetre C., Weigelt B., et al. A validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks. Breast Cancer Res Treat 2010, 120:83-93.
19. Lane R.D., Allan D.M., Mellgren R.L. A comparison of the intracellular distribution of μ-calpain, m-calpain, and calpastatin in proliferating human A431 cells. Exp Cell Res 1992, 203:5-16.
20. Camp R.L., Dolled-Filhart M., Rimm D.L. X-Tile: a new bioinformatics tool for biomarker assessment and outcome based cut point optimisation. Clin Cancer Res 2004, 10:7252-7259.
21. Glading A., Überall F., Keyse S.M., Lauffenburger D.A., Wells A. Membrane proximal ERK signalling is required for m-calpain activation downstream of epidermal growth factor receptor signalling. J Biol Chem 2001, 276:23341-23348.
22. Wendt A., Thompson V.F., Goll D.E. Interaction of calpastatin with calpain: a review. Biol Chem 2004, 385:465-472.
23. Huang Y., Wang K.K. The calpain family and human disease. Trends Mol Med 2001, 7:355-362.
24. Cortesio C.L., Chan K.T., Perrin B.J., Burton N., Zhang S., Zhang Z.-Y., et al. Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadiopodia dynamics and breast cancer cell invasion. J Cell Biol 2008, 180:957-971.
25. Carragher N.O., Walker S.M., Scott Carragher L.A., Harris F., Sawyer T.K., Brunton V.G., et al. Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function. Oncogene 2006, 25:5726-5740.
26. Huttenlocher A., Palecek S.P., Lu Q., Zhang W., Mellgren R.L., Lauffenburger D.A., et al. Regulation of cell migration by the calcium dependent protease calpain. J Biol Chem 1997, 272:32719-32722.
27. Popp O., Heidinger M., Ruiz-Heinrich L., Ries C., Jochum M., Gil-Parrado S. The calpastatin-derived calpain inhibitor CP1B reduces mRNA expression of matrix metalloproteinase-2 and -9 and invasion by leukaemic THP-1 cells. Biol Chem 2003, 384:951-958.
28. Lakshmikuttyamma A., Selvakumar P., Kanthan R., Chandra Kanthan S., Sharma R.K. Overexpression of m-calpain in human colorectal adenocarcinomas. Cancer Epidemiol Biomarkers Prev 2004, 13:1604-1609.
29. Vaisid T., Kosower N.S., Katzav A., Chapman J., Barnoy S. Calpastatin levels affect calpain activation and calpain proteolytic activity in APP transgenic mouse model of Alzheimer's disease. Neurochem Int 2007, 51:391-397.
30. Gonçalves I., Nitulescu M., Saido T.C., Dias N., Pedro L.M., E Fernandes J.F., et al. Activation of calpain-1 in human carotid artery atherosclerotic lesions. BMC Cardiovasc Disord 2009, 9:26.
31. Neumar R.W., Meng F.H., Mills A.M., Xu Y.A., Zhang C., Welsh F.A., et al. Calpain activity in rat brain after transient forebrain ischemia. Exp Neurol 2001, 170:27-35.
32. Raynaud P., Gillard M., Parr T., Bardsley R., Amarger V., Levéziel H. Correlation between bovine calpastatin mRNA transcripts and protein isoforms. Arch Biochem Biophys 2005, 440:46-53.
33. Lee W.J., Ma H., Yang H.Q., Hatanaka M., Maki M. Molecular diversity in amino terminal domains of human calpastatin by exon skipping. J Biol Chem 1992, 267:8437-8442.
34. Zhang H., Rakha E.A., Ball G.R., Spiteri I., Aleskandarany M., Paish E.C., et al. The proteins FABP7 and OATP2 are associated with the basal phenotype and patient outcome in human breast cancer. Breast Cancer Res Treat 2010, 121:41-51.
35. Niapour M., Yu Y., Berger S.A. Regulation of calpain activity by c-Myc through calpastatin and promotion of transformation in c-Myc-negative cells by calpastatin suppression. J Biol Chem 2008, 283:21371-21381.
36. Pozo-Guisado E., Merino J.M., Mulero-Navarro S., Lorenzo-Benayas M.J., Centeno F., Alvarez-Barrientos A., et al. Int J Cancer 2005, 115:74-84.
37. De Tullio R., Stifanese R., Salamino F., Pontremoli S., Melloni E. Characterisation of a new p94-like calpain form in human lymphocytes. Biochem J 2003, 375:689-696.
38. Chen J.-S., Coustan-Smith E., Suzuki T., Neale G.A., Mihara K., Pui C.H., et al. Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukaemia. Blood 2001, 97:2115-2120.
39. Kulkarni S., Reddy K.B., Esteva F.J., Moore H.J., Budd G.T., Tubbs R.R. Calpain regulates sensitivity to trastuzumab and survival in HER2 positive breast cancer. Oncogene 2009, 29:1339-1350.
40. Storr S.J., Woolston C.M., Barros F.F.T., Green G.R., Shehata M., Chan S.Y., et al. Calpain-1 expression is associated with relapse-free survival in breast cancer patients treated with trastuzumab following adjuvant chemotherapy. Int J Cancer 2011, 10.1002/ijc.25832.